1. Vinagre J, Almeida A, Pópulo H, Batista R, Lyra J, Pinto V, Coelho R, Celestino R, Prazeres H, Lima L, Melo M, Rocha AG, Preto A, Castro P, Castro L, Pardal F, Lopes JM, Santos LL, Reis RM, Cameselle-Teijeiro J, Sobrinho-Simões M, Lima J, Máximo V, Soares P

Frequency of TERT promoter mutations in human cancers. Nature communications 4: 2185, 2013.  [Article] 

 doi: 10.1038/ncomms3185 PMID: 23887589.

 

2. Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene 24: 7630-4, 2005.  [Article] 

 doi: 10.1038/sj.onc.1208906 PMID: 16007118.

 

3. Soares P, Trovisco V, Rocha AS, Lima J, Castro P, Preto A, Máximo V, Botelho T, Seruca R, Sobrinho-Simões M

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene 22: 4578-80, 2003.  [Article] 

 doi: 10.1038/sj.onc.1206706 PMID: 12881714.

 

4. Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S, Carneiro F, Seruca R

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene 26: 158-63, 2007.  [Article] 

 doi: 10.1038/sj.onc.1209758 PMID: 16953233.

 

5. Preto A, Singhrao SK, Haughton MF, Kipling D, Wynford-Thomas D, Jones CJ

Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy. Oncogene 23: 4136-45, 2004.  [Article] 

 doi: 10.1038/sj.onc.1207564 PMID: 15064743.

 

6. Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. The Journal of pathology 214: 320-7, 2008.  [Article] 

 doi: 10.1002/path.2295 PMID: 18098337.

 

7. Máximo V, Botelho T, Capela J, Soares P, Lima J, Taveira A, Amaro T, Barbosa AP, Preto A, Harach HR, Williams D, Sobrinho-Simões M

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid. British journal of cancer 92: 1892-8, 2005.  [Article] 

 doi: 10.1038/sj.bjc.6602547 PMID: 15841082.

 

8. Castro L, Alves S, Chaves SR, Costa JL, Soares P, Preto A

RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation. Molecular and cellular endocrinology 415: 64-75, 2015.  [Article] 

 doi: 10.1016/j.mce.2015.08.006 PMID: 26265449.

 

9. Xavier CP, Lima CF, Preto A, Seruca R, Fernandes-Ferreira M, Pereira-Wilson C

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer letters 281: 162-70, 2009.  [Article] 

 doi: 10.1016/j.canlet.2009.02.041 PMID: 19344998.

 

10. Preto A, Cameselle-Teijeiro J, Moldes-Boullosa J, Soares P, Cameselle-Teijeiro JF, Silva P, Reis-Filho JS, Reyes-Santías RM, Alfonsín-Barreiro N, Forteza J, Sobrinho-Simões M

Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 17: 819-26, 2004.  [Article] 

 doi: 10.1038/modpathol.3800124 PMID: 15044923.

 

11. Reis-Filho JS, Preto A, Soares P, Ricardo S, Cameselle-Teijeiro J, Sobrinho-Simões M

p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 16: 43-8, 2003.  [Article] 

 doi: 10.1097/01.MP.0000047306.72278.39 PMID: 12527712.

 

12. Preto A, Gonçalves J, Rebocho AP, Figueiredo J, Meireles AM, Rocha AS, Vasconcelos HM, Seca H, Seruca R, Soares P, Sobrinho-Simões M

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations. BMC cancer 9: 387, 2009.  [Article] 

 doi: 10.1186/1471-2407-9-387 PMID: 19878585.

 

13. Meireles AM, Preto A, Rocha AS, Rebocho AP, Máximo V, Pereira-Castro I, Moreira S, Feijão T, Botelho T, Marques R, Trovisco V, Cirnes L, Alves C, Velho S, Soares P, Sobrinho-Simões M

Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid : official journal of the American Thyroid Association 17: 707-15, 2007.  [Article] 

 doi: 10.1089/thy.2007.0097 PMID: 17725429.

 

14. Cameselle-Teijeiro J, Preto A, Soares P, Sobrinho-Simões M

A stem cell role for thyroid solid cell nests. Human pathology 36: 590-1, 2005.  [Letter] 

 doi: 10.1016/j.humpath.2005.02.010 PMID: 15948129.

 

15. Soares P, Lima J, Preto A, Castro P, Vinagre J, Celestino R, Couto JP, Prazeres H, Eloy C, Máximo V, Sobrinho-Simões M

Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas. Current genomics 12: 609-17, 2011.  [Article] 

 doi: 10.2174/138920211798120853 PMID: 22654560.

 

16. Soares P, Lima J, Preto A, Castro P, Vinagre J, Celestino R, Couto JP, Prazeres H, Eloy C, Máximo V, Sobrinho-Simões M

Alterations in Poorly Differentiated and Unddiferentiated Thyroid Carcinomas Current genomics  1, 2011.  [] 

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17. Reis-Filho JS, Simpson PT, Martins A, Preto A, Gärtner F, Schmitt FC

Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray. Virchows Archiv : an international journal of pathology 443: 122-32, 2003.  [Article] 

 doi: 10.1007/s00428-003-0859-2 PMID: 12884041.

 

18. Máximo V, Preto A, Crespo A, Rocha AS, Machado JC, Soares P, Sobrinho-Simões M

Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid. BMC cancer 4: 12, 2004.  [Article] 

 doi: 10.1186/1471-2407-4-12 PMID: 15043758.

 

19. Trovisco V, Soares P, Preto A, de Castro IV, Lima J, Castro P, Máximo V, Botelho T, Moreira S, Meireles AM, Magalhães J, Abrosimov A, Cameselle-Teijeiro J, Sobrinho-Simões M

Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients' age but not with tumour aggressiveness. Virchows Archiv : an international journal of pathology 446: 589-95, 2005.  [Article] 

 doi: 10.1007/s00428-005-1236-0 PMID: 15902486.

 

20. Sobrinho-Simões M, Preto A, Rocha AS, Castro P, Máximo V, Fonseca E, Soares P

Molecular pathology of well-differentiated thyroid carcinomas. Virchows Archiv : an international journal of pathology 447: 787-93, 2005.  [Review] 

 doi: 10.1007/s00428-005-0065-5 PMID: 16189702.

 

21. Sobrinho-Simões M, Máximo V, Rocha AS, Trovisco V, Castro P, Preto A, Lima J, Soares P

Intragenic mutations in thyroid cancer. Endocrinology and metabolism clinics of North America 37: 333-62, viii, 2008.  [Review] 

 doi: 10.1016/j.ecl.2008.02.004 PMID: 18502330.

 

22. Preto A, Moutinho C, Velho S, Oliveira C, Rebocho AP, Figueiredo J, Soares P, Lopes JM, Seruca R

A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation. Virchows Archiv : an international journal of pathology 450: 619-26, 2007.  [Article] 

 doi: 10.1007/s00428-007-0420-9 PMID: 17487504.

 

23. Preto A, Reis-Filho JS, Ricardo S, Soares P

P63 expression in papillary and anaplastic carcinomas of the thyroid gland: lack of an oncogenetic role in tumorigenesis and progression. Pathology, research and practice 198: 449-54, 2002.  [Article] 

 PMID: 12234063.

 

24. Trovisco V, Soares P, Preto A, Castro P, Máximo V, Sobrinho-Simões M

Molecular genetics of papillary thyroid carcinoma: great expectations. Arquivos brasileiros de endocrinologia e metabologia 51: 643-53, 2007.  [Review] 

 PMID: 17891228.

 

25. Preto A, Soares P, Sobrinho-Simões M

Novas terapêuticas no carcinoma da tireóide: novos alvos moleculares? Mundo Médico 54: 8-12, 2007.  [] 

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