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Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression. Nucleic acids research 45: e123, 2017.  [Article] 

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Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas. Cancer research 57: 634-40, 1997.  [Article] 

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Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. The Journal of biological chemistry 278: 51549-56, 2003.  [Article] 

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9. Almeida R, Almeida J, Shoshkes M, Mendes N, Mesquita P, Silva E, Van Seuningen I, Reis CA, Santos-Silva F, David L

OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells. The Journal of pathology 207: 396-401, 2005.  [Article] 

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10. Ruvoën-Clouet N, Magalhaes A, Marcos-Silva L, Breiman A, Figueiredo C, David L, Le Pendu J

Increase in Genogroup II.4 Norovirus Host Spectrum by CagA-Positive Helicobacter pylori Infection. The Journal of infectious diseases 210: 183-91, 2014.  [Article] 

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11. Camilo V, Barros R, Sousa S, Magalhães AM, Lopes T, Mário Santos A, Pereira T, Figueiredo C, David L, Almeida R

Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells. Carcinogenesis 33: 1985-92, 2012.  [Article] 

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12. Ricardo S, Marcos-Silva L, Pereira D, Pinto R, Almeida R, Söderberg O, Mandel U, Clausen H, Felix A, Lunet N, David L

Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours. Molecular oncology 9: 503-12, 2015.  [Article] 

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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer. Molecular oncology 12: 1639-1655, 2018.  [Article] 

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14. Magalhães A, Marcos-Pinto R, Nairn AV, Dela Rosa M, Ferreira RM, Junqueira-Neto S, Freitas D, Gomes J, Oliveira P, Santos MR, Marcos NT, Xiaogang W, Figueiredo C, Oliveira C, Dinis-Ribeiro M, Carneiro F, Moremen KW, David L, Reis CA

Helicobacter pylori chronic infection and mucosal inflammation switches the human gastric glycosylation pathways. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852: 1928-39, 2015.  [Article] 

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Infection by Helicobacter pylori expressing the BabA adhesin is influenced by the secretor phenotype. The Journal of pathology 215: 308-16, 2008.  [Article] 

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16. Barros R, Pereira B, Duluc I, Azevedo M, Mendes N, Camilo V, Jacobs RJ, Paulo P, Santos-Silva F, van Seuningen I, van den Brink GR, David L, Freund JN, Almeida R

Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines. The Journal of pathology 215: 411-20, 2008.  [Article] 

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17. Gomes C, Almeida A, Ferreira JA, Silva L, Santos-Sousa H, Pinto-de-Sousa J, Santos LL, Amado F, Schwientek T, Levery SB, Mandel U, Clausen H, David L, Reis CA, Osório H

Glycoproteomic analysis of serum from patients with gastric precancerous lesions. Journal of proteome research 12: 1454-66, 2013.  [Article] 

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18. Almeida R, Silva E, Santos-Silva F, Silberg DG, Wang J, De Bolós C, David L

Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. The Journal of pathology 199: 36-40, 2003.  [Article] 

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19. Burford B, Gentry-Maharaj A, Graham R, Allen D, Pedersen JW, Nudelman AS, Blixt O, Fourkala EO, Bueti D, Dawnay A, Ford J, Desai R, David L, Trinder P, Acres B, Schwientek T, Gammerman A, Reis CA, Silva L, Osório H, Hallett R, Wandall HH, Mandel U, Hollingsworth MA, Jacobs I, Fentiman I, Clausen H, Taylor-Papadimitriou J, Menon U, Burchell JM

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer. British journal of cancer 108: 2045-55, 2013.  [Article] 

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20. Pinto R, Carvalho AS, Conze T, Magalhães A, Picco G, Burchell JM, Taylor-Papadimitriou J, Reis CA, Almeida R, Mandel U, Clausen H, Söderberg O, David L

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation. Journal of cellular and molecular medicine 16: 1474-84, 2012.  [Article] 

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21. Pereira B, Oliveira C, David L, Almeida R

CDX2 promoter methylation is not associated with mRNA expression. International journal of cancer 125: 1739-42, 2009.  [Letter] 

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22. Mesquita P, Almeida R, Van Seuningen I, David L

Coordinated expression of MUC2 and CDX-2 in mucinous carcinomas of the lung can be explained by the role of CDX-2 as transcriptional regulator of MUC2. The American journal of surgical pathology 28: 1254-5, 2004.  [Letter] 

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23. David L, Silva F, Seruca R, Pinto M, Reis C, Sobrinho-Simões M

Correspondence re: A. E. Biemer-Huttmann et al., Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin. Cancer Res., 6: 1909-1916, 2000. Clinical cancer research : an official journal of the American Association for Cancer Research 6: 4461-2, 2000.  [Letter] 

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24. Peleteiro B, Lunet N, Figueiredo C, Carneiro F, David L, Barros H

Smoking, Helicobacter pylori virulence, and type of intestinal metaplasia in Portuguese males. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 16: 322-6, 2007.  [Article] 

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25. Teixeira A, David L, Reis CA, Costa J, Sobrinho-Simões M

Expression of mucins (MUC1, MUC2, MUC5AC, and MUC6) and type 1 Lewis antigens in cases with and without Helicobacter pylori colonization in metaplastic glands of the human stomach. The Journal of pathology 197: 37-43, 2002.  [Article] 

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26. Simpson RH, Prasad AR, Lewis JE, Skálová A, David L

Mucin-rich variant of salivary duct carcinoma: a clinicopathologic and immunohistochemical study of four cases. The American journal of surgical pathology 27: 1070-9, 2003.  [Article] 

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27. Koos B, Kamali-Moghaddam M, David L, Sobrinho-Simões M, Dimberg A, Nilsson M, Wählby C, Söderberg O

Next-generation pathology--surveillance of tumor microecology. Journal of molecular biology 427: 2013-22, 2015.  [Review] 

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28. Magalhães A, Gomes J, Ismail MN, Haslam SM, Mendes N, Osório H, David L, Le Pendu J, Haas R, Dell A, Borén T, Reis CA

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa. Glycobiology 19: 1525-36, 2009.  [Article] 

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29. Serpa J, Mendes N, Reis CA, Santos Silva LF, Almeida R, Le Pendu J, David L

Two new FUT2 (fucosyltransferase 2 gene) missense polymorphisms, 739G-->A and 839T-->C, are partly responsible for non-secretor status in a Caucasian population from Northern Portugal. The Biochemical journal 383: 469-74, 2004.  [Article] 

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30. Marcos-Silva L, Narimatsu Y, Halim A, Campos D, Yang Z, Tarp MA, Pereira PJ, Mandel U, Bennett EP, Vakhrushev SY, Levery SB, David L, Clausen H

Characterization of binding epitopes of CA125 monoclonal antibodies. Journal of proteome research 13: 3349-59, 2014.  [Article] 

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31. Pinto R, Barros R, Pereira-Castro I, Mesquita P, da Costa LT, Bennett EP, Almeida R, David L

CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia. Laboratory investigation; a journal of technical methods and pathology 95: 718-27, 2015.  [Article] 

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32. Barros R, Camilo V, Pereira B, Freund JN, David L, Almeida R

Pathophysiology of intestinal metaplasia of the stomach: emphasis on CDX2 regulation. Biochemical Society transactions 38: 358-63, 2010.  [Article; Proceedings Paper] 

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33. Conze T, Carvalho AS, Landegren U, Almeida R, Reis CA, David L, Söderberg O

MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas. Glycobiology 20: 199-206, 2010.  [Article] 

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34. Gomes J, Magalhães A, Carvalho AS, Hernandez GE, Papp SL, Head SR, Michel V, David L, Gärtner F, Touati E, Reis CA

Glycophenotypic Alterations Induced by Pteridium aquilinum in Mice Gastric Mucosa: Synergistic Effect with Helicobacter pylori Infection. PloS one 7: e38353, 2012.  [Article] 

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35. Coelho R, Marcos-Silva L, Mendes N, Pereira D, Brito C, Jacob F, Steentoft C, Mandel U, Clausen H, David L, Ricardo S

Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours. International journal of molecular sciences 19: ., 2018.  [Article] 

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36. Silva F, Carvalho F, Peixoto A, Teixeira A, Almeida R, Reis C, Bravo LE, Realpe L, Correa P, David L

MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritis. European journal of human genetics : EJHG 11: 380-4, 2003.  [Article] 

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37. Santos-Silva F, Fonseca A, Caffrey T, Carvalho F, Mesquita P, Reis C, Almeida R, David L, Hollingsworth MA

Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. Glycobiology 15: 511-7, 2005.  [Article] 

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38. Ricardo S, Marcos-Silva L, David L

Mucin carriers of TF in ovarian cancer. Journal of cancer research and clinical oncology 142: 1867-8, 2016.  [Letter] 

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39. Camilo V, Garrido M, Valente P, Ricardo S, Amaral AL, Barros R, Chaves P, Carneiro F, David L, Almeida R

Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2. Histopathology 66: 343-50, 2015.  [Article] 

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40. Carrilho C, Alberto M, Buane L, David L

Keratins 8, 10, 13, and 17 are useful markers in the diagnosis of human cervix carcinomas. Human pathology 35: 546-51, 2004.  [Article] 

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41. Mesquita P, Raquel A, Nuno L, Reis CA, Silva LF, Serpa J, Van Seuningen I, Barros H, David L

Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal metaplasia. Critical reviews in oncogenesis 12: 3-26, 2006.  [] 

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42. Reis CA, David L, Nielsen PA, Clausen H, Mirgorodskaya K, Roepstorff P, Sobrinho-Simões M

Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody. International journal of cancer 74: 112-21, 1997.  [Article] 

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43. Camilo V, Barros R, Celestino R, Castro P, Vieira J, Teixeira MR, Carneiro F, Pinto-de-Sousa J, David L, Almeida R

Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome. BMC cancer 14: 753, 2014.  [Article] 

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44. Peleteiro B, Lunet N, Santos-Silva F, David L, Figueiredo C, Barros H

Short mucin 1 alleles are associated with low virulent H pylori strains infection. World journal of gastroenterology : WJG 13: 1885-6, 2007.  [Letter] 

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45. Reis CA, David L, Seixas M, Burchell J, Sobrinho-Simões M

Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma. International journal of cancer 79: 402-10, 1998.  [Article] 

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46. Marcos-Silva L, Ricardo S, Chen K, Blixt O, Arigi E, Pereira D, Høgdall E, Mandel U, Bennett EP, Vakhrushev SY, David L, Clausen H

A novel monoclonal antibody to a defined peptide epitope in MUC16. Glycobiology 25: 1172-82, 2015.  [Article] 

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47. Serpa J, Mesquita P, Mendes N, Oliveira C, Almeida R, Santos-Silva F, Reis CA, LePendu J, David L

Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. Cancer letters 242: 191-7, 2006.  [Article] 

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48. Sadio A, Gustafsson JK, Pereira B, Gomes CP, Hansson GC, David L, Pêgo AP, Almeida R

Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier. PloS one 9: e99449, 2014.  [Article] 

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49. Silva F, Carvalho F, Peixoto A, Seixas M, Almeida R, Carneiro F, Mesquita P, Figueiredo C, Nogueira C, Swallow DM, Amorim A, David L

MUC1 gene polymorphism in the gastric carcinogenesis pathway. European journal of human genetics : EJHG 9: 548-52, 2001.  [Article] 

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50. Barros R, Mendes N, Howe JR, Reis CA, de Bolos C, Carneiro F, David L, Almeida R

Juvenile polyps have gastric differentiation with MUC5AC expression and downregulation of CDX2 and SMAD4. Histochemistry and cell biology 131: 765-72, 2009.  [Article] 

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51. Peleteiro B, Barros R, Carrilho C, Artiaga J, Cunha L, Modcoicar P, Ferreira R, Figueiredo C, Almeida R, La Vecchia C, David L, Barros H, Lunet N

Determinants of gastric CDX2 expression: a study in Mozambique. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 21: 532-540, 2012.  [Article] 

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52. Pinto-de-Sousa J, Silva F, David L, Leitão D, Seixas M, Pimenta A, Cardoso-de-Oliveira M

Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma. Histopathology 44: 323-31, 2004.  [Article] 

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53. Peleteiro B, Carrilho C, Modcoicar P, Cunha L, Ismail M, Guisseve A, Lorenzoni C, Fernandes F, Almeida R, Figueiredo C, David L

Chronic Atrophic Gastritis, Intestinal Metaplasia, Helicobacter pylori Virulence, IL1RN Polymorphisms, and Smoking in Dyspeptic Patients from Mozambique and Portugal Helicobacter 14: 306-308, 2009.  [Letter] 

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54. Pereira B, Oliveira C, David L, Almeida R

CDX2 Promoter Methylation is not Associated with mRNA Expression Helicobacter 14: 385-385, 2009.  [Meeting Abstract] 

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55. Camilo V, Barros R, Pereira B, Magalhaes A, Reis C, Freund J, David L, David L, Almeida R

BMP and H-pylori Downregulate SOX2 Expression in Gastric Cell Lines Helicobacter 14: 330-330, 2009.  [Meeting Abstract] 

.

 

56. Marcos NT, Magalhães A, Ferreira B, Oliveira M, Mendes N, Gilmartin T, Head S, Carvalho AS, Figueiredo C, David L, Santos-Silva F, Reis CA

H. pylori Induces beta 3GlcNAc-T5 in Gastric Epithelial Cells Leading to Expression of Sialyl-Lewis X, the Ligand for SabA Adhesin Helicobacter 14: 371, 2009.  [Meeting Abstract] 

.

 

57. Ricardo S, Marcos-Silva L, Valente C, Coelho R, Gomes R, David L

Mucins MUC16 and MUC1 are major carriers of SLe(a) and SLe(x) in borderline and malignant serous ovarian tumors. Virchows Archiv : an international journal of pathology 468: 715-22, 2016.  [Article] 

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58. Carrilho C, Gouveia P, Yokohama H, Lopes JM, Lunet N, Ferro J, Ismail M, Walboomers J, Sobrinho-Simões M, David L

Human papillomaviruses in intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva: a study from Mozambique. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 22: 566-8, 2013.  [Article] 

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59. Silva LM, Carvalho AS, Guillon P, Seixas S, Azevedo M, Almeida R, Ruvoën-Clouet N, Reis CA, Le Pendu J, Rocha J, David L

Infection-associated FUT2 (Fucosyltransferase 2) genetic variation and impact on functionality assessed by in vivo studies. Glycoconjugate journal 27: 61-8, 2010.  [Article] 

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60. Mesquita P, Peixoto AJ, Seruca R, Hanski C, Almeida R, Silva F, Reis C, David L

Role of site-specific promoter hypomethylation in aberrant MUC2 mucin expression in mucinous gastric carcinomas. Cancer letters 189: 129-36, 2003.  [Article] 

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61. Reis CA, David L, Carvalho F, Mandel U, de Bolós C, Mirgorodskaya E, Clausen H, Sobrinho-Simões M

Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 48: 377-88, 2000.  [Article] 

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62. Pintalhao M, Dias-Neto M, Peleteiro B, Lopes C, Figueiredo C, David L, Lunet N

Salt intake and type of intestinal metaplasia in helicobacter pylori-infected portuguese men. Nutrition and cancer 62: 1153-60, 2010.  [Article] 

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63. Reis CA, Osorio H, Silva L, Gomes C, David L

Alterations in glycosylation as biomarkers for cancer detection. Journal of clinical pathology 63: 322-9, 2010.  [Review] 

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64. Ferreira B, Marcos NT, David L, Nakayama J, Reis CA

Terminal alpha1,4-linked N-acetylglucosamine in Helicobacter pylori-associated intestinal metaplasia of the human stomach and gastric carcinoma cell lines. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 54: 585-91, 2006.  [Article] 

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65. Marcos NT, Cruz A, Silva F, Almeida R, David L, Mandel U, Clausen H, Von Mensdorff-Pouilly S, Reis CA

Polypeptide GalNAc-transferases, ST6GalNAc-transferase I, and ST3Gal-transferase I expression in gastric carcinoma cell lines. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 51: 761-71, 2003.  [Article] 

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66. Barros R, Pereira D, Callé C, Camilo V, Cunha AI, David L, Almeida R, Dias-Pereira A, Chaves P

Dynamics of SOX2 and CDX2 Expression in Barrett's Mucosa. Disease markers 2016: 1532791, 2016.  [Article] 

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67. Coelho R, Marcos-Silva L, Ricardo S, Ponte F, Costa A, Lopes JM, David L

Peritoneal dissemination of ovarian cancer: role of MUC16-mesothelin interaction and implications for treatment. Expert review of anticancer therapy 18: 177-186, 2018.  [Review] 

 doi: 10.1080/14737140.2018.1418326 PMID: 29241375.

 

68. Magalhães A, Marcos N T, Carvalho A S, David L, Figueiredo C, Bastos J, David G, Reis C

Helicobacter pylori cag pathogenicity island-positive strains induce syndecan-4 expression in gastric epithelial cells FEMS immunology and medical microbiology I: 1-10, 2009.  [Article] 

 doi: 10.1111/j.1574-695X.2009.00569.x PMID: 19519784.

 

69. Reis CA, Teixeira A, David L

Role of mucins in Helicobacter pylori adhesion to the gastric mucosa. Helicobacter 9: 181; author reply 181-2, 2004.  [Letter] 

 doi: 10.1111/j.1083-4389.2004.00216.x PMID: 15068421.

 

70. Carrilho C, Modcoicar P, Cunha L, Ismail M, Guisseve A, Lorenzoni C, Fernandes F, Peleteiro B, Almeida R, Figueiredo C, David L, Lunet N

Prevalence of Helicobacter pylori infection, chronic gastritis, and intestinal metaplasia in Mozambican dyspeptic patients. Virchows Archiv : an international journal of pathology 454: 153-60, 2009.  [Article] 

 doi: 10.1007/s00428-008-0713-7 PMID: 19101725.

 

71. Serpa J, Almeida R, Oliveira C, Silva FS, Silva E, Reis C, Le Pendu J, Oliveira G, Ribeiro LM, David L

Lewis enzyme (alpha1-3/4 fucosyltransferase) polymorphisms do not explain the Lewis phenotype in the gastric mucosa of a Portuguese population. Journal of human genetics 48: 183-9, 2003.  [Article] 

 doi: 10.1007/s10038-003-0007-5 PMID: 12730721.

 

72. Reis CA, Sørensen T, Mandel U, David L, Mirgorodskaya E, Roepstorff P, Kihlberg J, Hansen JE, Clausen H

Development and characterization of an antibody directed to an alpha-N-acetyl-D-galactosamine glycosylated MUC2 peptide. Glycoconjugate journal 15: 51-62, 1998.  [Article] 

 PMID: 9530956.

 

73. Pinto-de-Sousa J, Reis CA, David L, Pimenta A, Cardoso-de-Oliveira M

MUC5B expression in gastric carcinoma: relationship with clinico-pathological parameters and with expression of mucins MUC1, MUC2, MUC5AC and MUC6. Virchows Archiv : an international journal of pathology 444: 224-30, 2004.  [Article] 

 doi: 10.1007/s00428-003-0968-y PMID: 14758553.

 

74. Carrilho C, Cirnes L, Alberto M, Buane L, Mendes N, David L

Distribution of HPV infection and tumour markers in cervical intraepithelial neoplasia from cone biopsies of Mozambican women. Journal of clinical pathology 58: 61-8, 2005.  [Article] 

 doi: 10.1136/jcp.2004.020552 PMID: 15623485.

 

75. Barros R, Marcos N, Reis CA, De Luca A, David L, Almeida R

CDX2 expression is induced by Helicobacter pylori in AGS cells. Scandinavian journal of gastroenterology 44: 124-5, 2009.  [Letter] 

 doi: 10.1080/00365520802530846 PMID: 18991163.

 

76. Pinto-de-Sousa J, David L, Reis CA, Gomes R, Silva L, Pimenta A

Mucins MUC1, MUC2, MUC5AC and MUC6 expression in the evaluation of differentiation and clinico-biological behaviour of gastric carcinoma. Virchows Archiv : an international journal of pathology 440: 304-10, 2002.  [Article] 

 doi: 10.1007/s00428-001-0548-y PMID: 11889602.

 

77. Silva E, Teixeira A, David L, Carneiro F, Reis CA, Sobrinho-Simões J, Serpa J, Veerman E, Bolscher J, Sobrinho-Simões M

Mucins as key molecules for the classification of intestinal metaplasia of the stomach. Virchows Archiv : an international journal of pathology 440: 311-7, 2002.  [Article] 

 doi: 10.1007/s004280100531 PMID: 11889603.

 

78. Rodrigues JP, David L, Almeida R, Barros R, Freitas T, Silva J, Ponte A, Sousa M, Silva JC, Carvalho J

Mechanisms of regulation of normal and metaplastic intestinal differentiation. Histology and histopathology 33: 523-532, 2018.  [Review] 

 doi: 10.14670/HH-11-938 PMID: 29027178.

 

79. Carvalho F, Peixoto A, Steffensen R, Amorim A, David L, Sobrinho-Simões M

MUC1 gene polymorphism does not explain the different incidence of gastric cancer in Portugal and Denmark. Annals of human genetics 63: 187-91, 1999.  [Article] 

 PMID: 10738530.

 

80. Barros R, Peleteiro B, Almeida R, Figueiredo C, Barros H, David L, Lunet N

Relevance of high virulence Helicobacter pylori strains and futility of CDX2 expression for predicting intestinal metaplasia after eradication of infection. Scandinavian journal of gastroenterology 45: 828-34, 2010.  [Article] 

 doi: 10.3109/00365521003770269 PMID: 20367284.

 

81. Carneiro F, Machado JC, David L, Reis C, Nogueira AM, Sobrinho-Simões M

Current thoughts on the histopathogenesis of gastric cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 10: 101-2, 2001.  [Article; Proceedings Paper] 

 PMID: 11263582.

 

82. David L, Teixeira A, Reis C, Peixoto A, Carvalho F, Silva F, Sobrinho-Simões M

Gene-environment interactions in the stomach: role of mucins in Helicobacter pylori adhesion to normal and metaplastic mucosa of the stomach. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1: 103, 2001.  [Article; Proceedings Paper] 

.

 

83. Carvalho F, David L, Aubert JP, López-Ferrer A, De Bolós C, Reis CA, Gärtner F, Peixoto A, Alves P, Sobrinho-Simões M

Mucins and mucin-associated carbohydrate antigens expression in gastric carcinoma cell lines. Virchows Archiv : an international journal of pathology 435: 479-85, 1999.  [Article] 

 PMID: 10592051.

 

84. Sousa AM, Grandgenett PM, David L, Almeida R, Hollingsworth MA, Santos-Silva F

Reflections on MUC1 glycoprotein: the hidden potential of isoforms in carcinogenesis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 124: 913-924, 2016.  [Review] 

 doi: 10.1111/apm.12587 PMID: 27538373.

 

85. Carvalho F, Seruca R, David L, Amorim A, Seixas M, Bennett E, Clausen H, Sobrinho-Simões M

MUC1 gene polymorphism and gastric cancer--an epidemiological study. Glycoconjugate journal 14: 107-11, 1997.  [Article] 

 PMID: 9076520.

 

86. Nogueira AM, Marques T, Soares PC, David L, Reis CA, Serpa J, Queiroz DM, Rocha GA, Rocha AC

Lewis antigen expression in gastric mucosa of children: relationship with Helicobacter pylori infection. Journal of pediatric gastroenterology and nutrition 38: 85-91, 2004.  [Article] 

 PMID: 14676601.

 

87. Carrilho C, Cantel M, Gouveia P, David L

Simple mucin-type carbohydrate antigens (Tn, sialosyl-Tn, T and sialosyl-T) and gp 230 mucin-like glycoprotein are candidate markers for neoplastic transformation of the human cervix. Virchows Archiv : an international journal of pathology 437: 173-9, 2000.  [Article] 

 PMID: 10993278.

 

88. Serpa J, Lunet N, Mendes N, Barros H, David L

Lewis and Secretor status and Helicobacter pylori eradication. Epidemiology and infection 132: 997-8; author reply 998-9, 2004.  [Letter] 

 PMID: 15473165.

 

89. Lunet N, Valbuena C, Vieira AL, Lopes C, Lopes C, David L, Carneiro F, Barros H

Fruit and vegetable consumption and gastric cancer by location and histological type: case-control and meta-analysis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 16: 312-27, 2007.  [Article] 

 doi: 10.1097/01.cej.0000236255.95769.22 PMID: 17554204.

 

90. Sousa AM, Rei M, Freitas R, Ricardo S, Caffrey T, David L, Almeida R, Hollingsworth MA, Santos-Silva F

Effect of MUC1/ß-catenin interaction on the tumorigenic capacity of pancreatic CD133(+) cells. Oncology letters 12: 1811-1817, 2016.  [Article] 

 doi: 10.3892/ol.2016.4888 PMID: 27602113.

 

91. Marques T, David L, Reis C, Nogueira A

Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseases. Pathology, research and practice 201: 665-72, 2005.  [Article] 

 doi: 10.1016/j.prp.2005.03.007 PMID: 16325508.

 

92. Castro P, David L, Soares P, Carneiro F, Fonseca E, Sobrinho-Simões M

Vascular invasion in thyroid and gastric carcinomas. Ultrastructural pathology 27: 41-8, 2003.  [Article; Proceedings Paper] 

 PMID: 12554535.

 

93. Carrilho C, Gouveia P, Cantel M, Alberto M, Buane L, David L

Characterization of human papillomavirus infection, P53 and Ki-67 expression in cervix cancer of Mozambican women. Pathology, research and practice 199: 303-11, 2003.  [Article] 

 PMID: 12908520.

 

94. Pinto-De-Sousa J, David L, Seixas M, Pimenta A

Clinicopathologic profiles and prognosis of gastric carcinomas from the cardia, fundus/body and antrum. Digestive surgery 18: 102-10, 2001.  [Article] 

 PMID: 11351154.

 

95. Pinto-de-Sousa J, David L, Almeida R, Leitão D, Preto JR, Seixas M, Pimenta A

c-erb B-2 expression is associated with tumor location and venous invasion and influences survival of patients with gastric carcinoma. International journal of surgical pathology 10: 247-56, 2002.  [Article] 

 PMID: 12490974.

 

96. da Silva LF, David L, Ribeiro D, Felino A

Odontomas: a clinicopathologic study in a Portuguese population. Quintessence international (Berlin, Germany : 1985) 40: 61-72, 2009.  [Article] 

 PMID: 19159025.

 

97. Peltomäki P, Lothe RA, Aaltonen LA, Pylkkänen L, Nyström-Lahti M, Seruca R, David L, Holm R, Ryberg D, Haugen A

Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer research 53: 5853-5, 1993.  [Note] 

 PMID: 8261393.

 

98. Seruca R, Santos NR, David L, Constância M, Barroca H, Carneiro F, Seixas M, Peltomäki P, Lothe R, Sobrinho-Simões M

Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile. International journal of cancer 64: 32-6, 1995.  [Article] 

 PMID: 7665246.

 

99. David L, Nesland JM, Clausen H, Carneiro F, Sobrinho-Simões M

Simple mucin-type carbohydrate antigens (Tn, sialosyl-Tn and T) in gastric mucosa, carcinomas and metastases. APMIS. Supplementum 27: 162-72, 1992.  [Article] 

 PMID: 1520525.

 

100. David L, Nesland JM, Holm R, Sobrinho-Simões M

Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients. Cancer 73: 518-27, 1994.  [Article] 

 PMID: 8299074.

 

101. Seruca R, David L, Holm R, Nesland JM, Fangan BM, Castedo S, Sobrinho-Simões M, Børresen AL

P53 mutations in gastric carcinomas. British journal of cancer 65: 708-10, 1992.  [Note] 

 PMID: 1586599.

 

102. Carneiro F, David L, Seruca R, Castedo S, Nesland JM, Sobrinho-Simões M

Hyperplastic polyposis and diffuse carcinoma of the stomach. A study of a family. Cancer 72: 323-9, 1993.  [Article] 

 PMID: 8319165.

 

103. Carneiro F, Santos L, David L, Dabelsteen E, Clausen H, Sobrinho-Simões M

T (Thomsen-Friedenreich) antigen and other simple mucin-type carbohydrate antigens in precursor lesions of gastric carcinoma. Histopathology 24: 105-13, 1994.  [Article] 

 PMID: 8181802.

 

104. Seruca R, Suijkerbuijk RF, Gärtner F, Criado B, Veiga I, Olde-Weghuis D, David L, Castedo S, Sobrinho-Simões M

Increasing levels of MYC and MET co-amplification during tumor progression of a case of gastric cancer. Cancer genetics and cytogenetics 82: 140-5, 1995.  [Article] 

 PMID: 7664243.

 

105. Ramires M, David L, Leitão D, Seixas M, Sansonetty F, Sobrinho-Simões M

Ki67 labelling index in gastric carcinomas. An immunohistochemical study using double staining for the evaluation of the proliferative activity of diffuse-type carcinomas. The Journal of pathology 182: 62-7, 1997.  [Article] 

 doi: 10.1002/(SICI)1096-9896(199705)182:1<62::AID-PATH849>3.0.CO;2-2 PMID: 9227343.

 

106. David L, Seruca R, Nesland JM, Soares P, Sansonetty F, Holm R, Børresen AL, Sobrinho-Simões M

c-erbB-2 expression in primary gastric carcinomas and their metastases. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 5: 384-90, 1992.  [Article] 

 PMID: 1353880.

 

107. Gärtner F, David L, Seruca R, Machado JC, Sobrinho-Simões M

Establishment and characterization of two cell lines derived from human diffuse gastric carcinomas xenografted in nude mice. Virchows Archiv : an international journal of pathology 428: 91-8, 1996.  [Article] 

 PMID: 8925130.

 

108. David L, Leitao D, Sobrinho-Simoes M, Bennett EP, White T, Mandel U, Dabelsteen E, Clausen H

Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals. Cancer research 53: 5494-500, 1993.  [Article] 

 PMID: 8221689.

 

109. Carneiro F, Moutinho-Ribeiro M, David L, Seixas M, Sansonetty F, Soares P, Serrano A, Sobrinho-Simões M

Signet ring cell carcinoma of the stomach: a morphometric, ultrastructural, and DNA cytometric study. Ultrastructural pathology 16: 603-14, 1992.  [Article] 

 PMID: 1333109.

 

110. Seruca R, Carneiro F, Castedo S, David L, Lopes C, Sobrinho-Simões M

Familial gastric polyposis revisited. Autosomal dominant inheritance confirmed. Cancer genetics and cytogenetics 53: 97-100, 1991.  [Article] 

 PMID: 1645228.

 

111. Silva F, Gusmão L, Alves C, Seruca R, David L, Amorim A

Tetra- and pentanucleotide short tandem repeat instability in gastric cancer. Electrophoresis 18: 1633-6, 1997.  [Article; Proceedings Paper] 

 doi: 10.1002/elps.1150180926 PMID: 9378135.

 

112. Castedo S, Correia C, David L, Sobrinho-Simões M

Isochromosome 8q. A recurrent change in gastric carcinoma. Cancer genetics and cytogenetics 54: 137-8, 1991.  [Letter] 

 PMID: 2065310.

 

113. Garcia E, Carvalho F, Amorim A, David L

MUC6 gene polymorphism in healthy individuals and in gastric cancer patients from northern Portugal. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 6: 1071-4, 1997.  [Article] 

 PMID: 9419405.

 

114. David L, Mandel U, Clausen H, Sobrinho-Simões M

Immunohistochemical expression of oncofetal fibronectin in benign and malignant lesions of the stomach. European journal of cancer (Oxford, England : 1990) 29A: 2070-1, 1993.  [Letter] 

 PMID: 8280503.

 

115. Carneiro F, Amado M, David L, Clausen H, Sobrinho-Simões M

Glycosylation features of gastric carcinoma initiation and progression. A review with emphasis on simple mucin-type carbohydrates and histo-blood group antigens of the Lewis system. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 3 Suppl 2: 39-46, 1994.  [Proceedings Paper] 

 PMID: 7735044.

 

116. Seruca R, David L, Castedo S, Veiga I, Børresen AL, Sobrinho-Simões M

p53 alterations in gastric carcinoma: a study of 56 primary tumors and 204 nodal metastases. Cancer genetics and cytogenetics 75: 45-50, 1994.  [Article] 

 PMID: 8039163.

 

117. Carneiro F, David L, Sunkel C, Lopes C, Sobrinho-Simões M

Immunohistochemical analysis of ras oncogene p21 product in human gastric carcinomas and their adjacent mucosas. Pathology, research and practice 188: 263-72, 1992.  [Article] 

 PMID: 1625989.

 

118. David L, Nesland JM, Funderud S, Sobrinho-Simões M

CDw75 antigen expression in human gastric carcinoma and adjacent mucosa. Cancer 72: 1522-7, 1993.  [Article] 

 PMID: 8348485.

 

119. Carneiro F, David L, Sobrinho-Simões M

Sialyl-Tn expression in gastric carcinoma. European journal of cancer (Oxford, England : 1990) 30A: 1398-9, 1994.  [Letter] 

 PMID: 7999432.

 

120. Marinho A, Moura A, Baptista M, Macedo G, Pimenta A, David L

Granular cell tumour and leiomyomatosis of the esophagus--a non-coincidental association? Pathology, research and practice 192: 492-5, 1996.  [Article] 

 PMID: 8832756.

 

121. David L, Carneiro F, Sobrinho-Simões M

Sialosyl Tn antigen expression is associated with the prognosis of patients with advanced gastric cancer. Cancer 78: 177-8, 1996.  [Letter] 

 doi: 10.1002/(SICI)1097-0142(19960701)78:1<177::AID-CNCR24>3.0.CO;2-W PMID: 8646715.

 

122. David L, Sobrinho Simões M

Tenascin and oncofetal fibronectin--oncofetal markers or indicators of extracellular matrix remodelling? British journal of cancer 74: 990-1, 1996.  [Letter] 

 PMID: 8826873.

 

123. Carneiro F, David L, Sobrinho-Simões M

Prognostic significance of T antigen expression in patients with gastric carcinoma. Cancer 78: 2448-50, 1996.  [Letter] 

 PMID: 8941019.

 

124. David L, Sobrinho-Simões M

Intracytoplasmic bodies in the myocardium. Ultrastructural pathology 12: 357-63, 1988.  [Discussion] 

 PMID: 2840768.

 

125. Nogueira C, Figueiredo C, Carneiro F, David L, Peixoto A, Cardoso de Oliveira M, Taveira Gomes A, Barreira R, Tomé Ribeiro A, Salgado C, Figueira P, Belo L, Ribeiro AM, Lomba C, Pitta MF, Monteiro ML, Nina N, Gonçalves G, Quint WGV, van Doorn LJ, Sobrinho-Simões M

Associação entre os genótipos de Helicobacter pylori e o desenvolvimento de gastrite crónica atrófica e metaplasia intestinal. Primeiros resultados de uma acção de rastreio. Jornal Português de Gastrenterologia 7: 138-146, 2000.  [] 

.

 

126. David L, Sobrinho-Simões M

Tumours of the parathyroid gland. UICC Comprehensive Tumour Terminology Handbook 1: 33-35, 2001.  [] 

.

 

127. Bastos J, David L, Sobrinho Simões M

Neoplasias e processos neoplasiformes retroperitoneais. Revisão clinico-patológica de 64 casos com recurso a métodos complementares de diagnóstico Arquivos de Medicina 3: 381-387, 1990.  [] 

.

 

128. Seruca R, David L, Sobrinho-Simões M

Relationship between the expression of p53 and the aggressiveness of gastric carcinoma. The Journal of pathology 181: 349, 1997.  [Letter] 

 doi: 10.1002/(SICI)1096-9896(199703)181:3<349::AID-PATH776>3.0.CO;2-S PMID: 9155724.

 

129. Pinto de Sousa J, David L

Role of immunohistochemical expression of MUC5B in gastric carcinoma. In: Handbook of immunohistochemistry and in situ hybridization of human carcinomas. Handbook of immunohistochemistry and in situ hybridization of human carcinomas 4 4: 191-194, 2006.  [] 

.

 

130. David L, Sobrinho-Simões M

Tumours of the thyroid gland. UICC Comprehensive Tumour Terminology Handbook 1: 23-32, 2001.  [] 

.

 

131. David L, Gärtner F, Sobrinho-Simões M

Do cathepsins play a role in the biological behavior of gastric carcinoma? Human pathology 27: 997-8, 1996.  [Letter] 

 PMID: 8816902.

 

132. Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, Defrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues. Frontiers in bioscience (Elite edition) 3: 1443-55, 2011.  [] 

 PMID: 21622148.

 

133. Sobrinho-Simões M, Carneiro F, David L, Soares P, Seruca R

A proeminência da morfologia e a quasi-futilidade das análises genéticas e moleculares no dia-a-dia da patologia oncológica. Revista da Faculdade de Medicina de Lisboa 4:  93-102, 1999.  [] 

.