1. Machado JC, Reis J, Fernandes M, Silva R, Cirnes L, Chaudhary R, Carneiro F, Costa JL

Determining tumor mutation load using an NGS-based, target gene panel European journal of cancer (Oxford, England : 1990) 92: S4-S5, 2018.  [Meeting Abstract] 

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2. Machado JC, Reis J, Fernandes M, Silva R, Cirnes L, Carneiro F, Costa JL

Tumor-specific neoantigens drive T-cell clonotype convergence European journal of cancer (Oxford, England : 1990) 92: S11-S11, 2018.  [Meeting Abstract] 

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3. Debruyne PR, Vermeulen SJ, Berx G, Pocard M, Correia da Rocha AS, Li X, Cirnes L, Poupon MF, van Roy FM, Mareel MM

Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. Oncogene 22: 7199-208, 2003.  [Article] 

 doi: 10.1038/sj.onc.1206628 PMID: 14562048.

 

4. Davalos V, Dopeso H, Velho S, Ferreira AM, Cirnes L, Díaz-Chico N, Bilbao C, Ramírez R, Rodríguez G, Falcón O, León L, Niessen RC, Keller G, Dallenbach-Hellweg G, Espín E, Armengol M, Plaja A, Perucho M, Imai K, Yamamoto H, Gebert JF, Díaz-Chico JC, Hofstra RM, Woerner SM, Seruca R, Schwartz S, Arango D

High EPHB2 mutation rate in gastric but not endometrial tumors with microsatellite instability. Oncogene 26: 308-11, 2007.  [Article] 

 doi: 10.1038/sj.onc.1209780 PMID: 16819508.

 

5. Carvalho R, Milne AN, van Rees BP, Caspers E, Cirnes L, Figueiredo C, Offerhaus GJ, Weterman MA

Early-onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age. The Journal of pathology 204: 75-83, 2004.  [Article] 

 doi: 10.1002/path.1602 PMID: 15307140.

 

6. Costa JL, Sousa S, Justino A, Kay T, Fernandes S, Cirnes L, Schmitt F, Machado JC

Nonoptical massive parallel DNA sequencing of BRCA1 and BRCA2 genes in a diagnostic setting. Human mutation 34: 629-35, 2013.  [Article] 

 doi: 10.1002/humu.22272 PMID: 23315985.

 

7. Pinto M, Oliveira C, Cirnes L, Carlos Machado J, Ramires M, Nogueira A, Carneiro F, Seruca R

Promoter methylation of TGFbeta receptor I and mutation of TGFbeta receptor II are frequent events in MSI sporadic gastric carcinomas. The Journal of pathology 200: 32-8, 2003.  [Article] 

 doi: 10.1002/path.1327 PMID: 12692838.

 

8. Justino A, Dias P, João Pina M, Sousa S, Cirnes L, Berta Sousa A, Carlos Machado J, Costa JL

Comprehensive massive parallel DNA sequencing strategy for the genetic diagnosis of the neuro-cardio-facio-cutaneous syndromes. European journal of human genetics : EJHG 23: 347-53, 2015.  [Article] 

 doi: 10.1038/ejhg.2014.97 PMID: 24896146.

 

9. Pinto M, Oliveira C, Machado JC, Cirnes L, Tavares J, Carneiro F, Hamelin R, Hofstra R, Seruca R, Sobrinho-Simões M

MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile. Laboratory investigation; a journal of technical methods and pathology 80: 1915-23, 2000.  [Article] 

 PMID: 11140703.

 

10. Nogueira AM, Carneiro F, Seruca R, Cirnes L, Veiga I, Machado JC, Sobrinho-Simões M

Microsatellite instability in hyperplastic and adenomatous polyps of the stomach. Cancer 86: 1649-56, 1999.  [Article] 

 PMID: 10547536.

 

11. Carvalho B, Pinto M, Cirnes L, Oliveira C, Machado JC, Suriano G, Hamelin R, Carneiro F, Seruca R

Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas. European journal of cancer (Oxford, England : 1990) 39: 1222-7, 2003.  [Article] 

 PMID: 12763209.

 

12. Schmitt FC, Soares R, Gobbi H, Milanezzi F, Santos-Silva F, Cirnes L, Costa C, Seruca R

Microsatellite instability in medullary breast carcinomas. International journal of cancer 82: 644-7, 1999.  [Article] 

 PMID: 10417760.

 

13. Oliveira C, Ferreira P, Nabais S, Campos L, Ferreira A, Cirnes L, Alves CC, Veiga I, Fragoso M, Regateiro F, Dias LM, Moreira H, Suriano G, Machado JC, Lopes C, Castedo S, Carneiro F, Seruca R

E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. European journal of cancer (Oxford, England : 1990) 40: 1897-903, 2004.  [Article] 

 doi: 10.1016/j.ejca.2004.04.027 PMID: 15288293.

 

14. Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis? BMC cancer 8: 255, 2008.  [Article] 

 doi: 10.1186/1471-2407-8-255 PMID: 18782444.

 

15. Veiga N, Pereira C, Resende C, Amaral O, Ferreira M, Nelas P, Chaves C, Duarte J, Cirnes L, Machado JC, Ferreira P, Correia IJ

Oral and Gastric Helicobacter Pylori: Effects and Associations PloS one 10: ., 2015.  [Article] 

 doi: 10.1371/journal.pone.0126923.

 

16. Meireles AM, Preto A, Rocha AS, Rebocho AP, Máximo V, Pereira-Castro I, Moreira S, Feijão T, Botelho T, Marques R, Trovisco V, Cirnes L, Alves C, Velho S, Soares P, Sobrinho-Simões M

Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid : official journal of the American Thyroid Association 17: 707-15, 2007.  [Article] 

 doi: 10.1089/thy.2007.0097 PMID: 17725429.

 

17. Aguiar F, Fernandes G, Queiroga H, Machado JC, Cirnes L, Souto Moura C, Hespanhol V

Overall Survival Analysis and Characterization of an EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) Population. Archivos de bronconeumologia 54: 10-17, 2018.  [Article] 

 doi: 10.1016/j.arbres.2017.07.012 PMID: 29079040.

 

18. Bertagnolli AC, Soares P, van Asch B, Amorim A, Cirnes L, Máximo V, Cassali GD

An assessment of the clonality of the components of canine mixed mammary tumours by mitochondrial DNA analysis. Veterinary journal (London, England : 1997) 182: 269-74, 2009.  [Article] 

 doi: 10.1016/j.tvjl.2008.07.005 PMID: 18752974.

 

19. Pinto C, Veiga I, Pinheiro M, Peixoto A, Pinto A, Lopes JM, Reis RM, Oliveira C, Baptista M, Roque L, Regateiro F, Cirnes L, Hofstra RM, Seruca R, Castedo S, Teixeira MR

TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset. Familial cancer 8: 383-90, 2009.  [Article] 

 doi: 10.1007/s10689-009-9251-y PMID: 19468865.

 

20. Carrilho C, Cirnes L, Alberto M, Buane L, Mendes N, David L

Distribution of HPV infection and tumour markers in cervical intraepithelial neoplasia from cone biopsies of Mozambican women. Journal of clinical pathology 58: 61-8, 2005.  [Article] 

 doi: 10.1136/jcp.2004.020552 PMID: 15623485.

 

21. Corso G, Roviello F, Paredes J, Pedrazzani C, Novais M, Correia J, Marrelli D, Cirnes L, Seruca R, Oliveira C, Suriano G

Characterization of the P373L E-cadherin germline missense mutation and implication for clinical management. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 33: 1061-7, 2007.  [Article] 

 doi: 10.1016/j.ejso.2007.03.001 PMID: 17434710.

 

22. Lopes JM, Silva P, Seixas M, Cirnes L, Seruca R

Microsatellite instability is not associated with degree of malignancy and p53 expression of gastrointestinal stromal tumours. Histopathology 33: 579-81, 1998.  [Letter] 

 PMID: 9870157.

 

23. Rossi ED, Gerhard R, Cirnes L, Machado JC, Schmitt F

Detection of common and less frequent EGFR mutations in cytological samples of lung cancer. Acta cytologica 58: 275-80, 2014.  [] 

 doi: 10.1159/000363174 PMID: 24924582.

 

24. Pinto M, Wu Y, Mensink RG, Cirnes L, Seruca R, Hofstra RM

Somatic mutations in mismatch repair genes in sporadic gastric carcinomas are not a cause but a consequence of the mutator phenotype. Cancer genetics and cytogenetics 180: 110-4, 2008.  [Article] 

 doi: 10.1016/j.cancergencyto.2007.09.022 PMID: 18206535.

 

25. Barroca HM, Cirnes L, Lopes JM

Metanephric adenoma: Cytological, histological, and molecular diagnosis of a case. Diagnostic cytopathology 44: 263-6, 2016.  [Letter] 

 doi: 10.1002/dc.23427 PMID: 26800350.

 

26. Barroca H, Carvalho JL, da Costa MJ, Cirnes L, Seruca R, Schmitt FC

Detection of N-myc amplification in neuroblastomas using Southern blotting on fine needle aspirates. Acta cytologica 45: 169-72, 2001.  [Article] 

 PMID: 11284301.

 

27. Schmitt FC, Soares R, Cirnes L, Seruca R

P53 in breast carcinomas: association between presence of mutation and immunohistochemical expression using a semiquantitative approach. Pathology, research and practice 194: 815-9, 1998.  [Article] 

 PMID: 9894246.

 

28. Schmitt FC, Soares R, Cirnes L, Seruca R

PCR amplification of DNA obtained from archived hematoxylin-eosin--and giemsa-stained breast cancer aspirates. Diagnostic cytopathology 19: 395-7, 1998.  [Article] 

 doi: 10.1002/(SICI)1097-0339(199811)19:5<395::AID-DC19>3.0.CO;2-4 PMID: 9812239.

 

29. Bertagnolli AC, Máximo V, Van Asch B, Amorim A, Cirnes L, Soares P, Cassali GD

Optimization of methods to assess mitochondrial DNA in archival paraffin-embedded tissues from mammary canine tumors Jornal  Brasileiro de  Patologia  305-308, 2008.  [] 

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30. Nogueira A, Carneiro F, Fernandes A, Seruca R, Cirnes L, Chaves P, Silva S, Lopes C, Martins MI, Baptista A

Características fenotípicas e moleculares da displasia gástrica. Revista Portuguesa de Gastrenterologia 10: 280-287, 2003.  [] 

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