João Vinagre
Name: João Vinagre
E-mail: jvinagre@i3s.up.pt
Extension: 
225570700
Academic Degree: PhD


João Vinagre
João Vinagre
Member of
Assistant Researcher of Cancer Signalling & Metabolism
Consultant of Ipatimup Diagnostics


Short CV
Faculty of Biotechnology – Portuguese Catholic University
Degree in Microbiology, 2006
PhD student: Programa Doutoral Ciências Veterinárias – Instituto Ciências Biomedicas Abel Salazar

Pópulo H, Vinagre J, Lopes JM, Soares P: ""Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas"". British Journal of Ophthalmology 2011 May;95(5):715-9; Epub 2010 Aug 30.

Eloy C, Vinagre J, Cameselle-Teijeiro J, Paiva ME, Soares P, Sobrinho-Simões M. : ""Tumor-in-Tumor of the Thyroid With Basaloid Differentiation: A Lesion With a Solid Cell Nest Neoplastic Component?"" Int J Surg Pathol. 2011 Apr;19(2):276-80.

Cruz J, Eloy C, Aragüés JM, Vinagre J, Sobrinho-Simões M.: “Small cell (basaloid) thyroid carcinoma – A neoplasm with a solid cell nest histogenesis?”. International Journal of Surgical Pathology. 2011 Apr 28.

Alvarenga CA, Lopes JM, Vinagre J, Paravidino PI, Alvarenga M, Prando A, Castilho LN, Soares P, Billis A:Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review. São Paulo Medical Journal 2012;130(1):57-60.


Celestino R, Lima J, Faustino A, Máximo V, Gouveia A, Vinagre J, Soares P, Lopes JM.: ""A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney-Stratakis dyad."" Fam Cancer. 2012 Jun;11(2):189-94.

Celestino R, Lima J, Faustino A, Vinagre J, Máximo V, Gouveia A, Soares P, Manuel Lopes J. Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors. Eur J Hum Genet. 2012 Sep 5. doi: 1038/ejhg.2012.205. [Epub ahead of print]

Alvelos MI, Vinagre J, Fonseca E, Barbosa E, Teixeira-Gomes J, Sobrinho-Simões M, Soares P. MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism. Eur J Endocrinol. 2012 Oct 23. [Epub ahead of print]

Highlights
Neuroendocrine tumors oncobiology. Thyroid pathology.

Supervisor of
Raquel Borges, Master Student (thesis)
MSc student
Beatriz Silva, Master Student (theoretical phase)
MSc student
Gabriela Silva, Research Trainee
Research Trainee
Lia Rodrigues, PhD Student
PhD student
Mafalda Gonçalves, Junior Researcher
Junior Researcher

PI (running)

PI (closed)
First Author
 
C
IF
1. Vinagre J, Pinheiro J, Martinho O, Reis RM, Preto J, Soares P, Lopes JM
 
2. Vinagre J, Nabais J, Pinheiro J, Batista R, Oliveira RC, Gonçalves AP, Pestana A, Reis M, Mesquita B, Pinto V, Lyra J, Cipriano MA, Ferreira MG, Lopes JM, Sobrinho-Simões M, Soares P
 doi: 10.1038/srep29714 PMID: 27411289.
 
3. Vinagre J, Pinto V, Celestino R, Reis M, Pópulo H, Boaventura P, Melo M, Catarino T, Lima J, Lopes JM, Máximo V, Sobrinho-Simões M, Soares P
Telomerase promoter mutations in cancer: an emerging molecular biomarker? Virchows Archiv : an international journal of pathology 465: 119-33, 2014. [Review] 
 
4. Vinagre J, Almeida A, Pópulo H, Batista R, Lyra J, Pinto V, Coelho R, Celestino R, Prazeres H, Lima L, Melo M, Rocha AG, Preto A, Castro P, Castro L, Pardal F, Lopes JM, Santos LL, Reis RM, Cameselle-Teijeiro J, Sobrinho-Simões M, Lima J, Máximo V, Soares P
Frequency of TERT promoter mutations in human cancers. Nature communications 4: 2185, 2013. [Article] 
 doi: 10.1038/ncomms3185 PMID: 23887589.
 
5. Celestino R, Lima J, Faustino A, Máximo V, Gouveia A, Vinagre J, Soares P, Lopes JM
 
Senior Author
 
C
IF
1. Gaspar TB, Macedo S, Sá A, Soares MA, Rodrigues DF, Sousa M, Mendes N, Martins RS, Cardoso L, Borges I, Canberk S, Gärtner F, Miranda-Alves L, Sobrinho-Simões M, Lopes JM, Soares P, Vinagre J
 
An update on genetically engineered mouse models of pancreatic neuroendocrine neoplasms. Endocrine-related cancer 29: R191-R208, 2022. [Review] 
 doi: 10.1530/ERC-22-0166 PMID: 36197786.
 
DGCR8 Microprocessor Subunit Mutation and Expression Deregulation in Thyroid Lesions. International journal of molecular sciences 23: ., 2022. [Article] 
 
4. Gaspar TB, Pinheiro J, Canberk S, Ince U, Tokat F, Lopes JM, Maximo V, Soares P, Vinagre J
.
 
Telomere Maintenance Mechanisms in Cancer. Genes 9: ., 2018. [Review] 
 
Editorial on "The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma" TRANSLATIONAL CANCER RESEARCH 7: S762-S765, 2018. [Editorial Material] 
 
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