1. Velho S, Fernandes MS, Leite M, Figueiredo C, Seruca R

Causes and consequences of microsatellite instability in gastric carcinogenesis. World journal of gastroenterology 20: 16433-42, 2014. [Article] 

 doi: 10.3748/wjg.v20.i44.16433 PMID: 25469011.

 

2. Velho S, Pinto A, Licastro D, Oliveira MJ, Sousa F, Stupka E, Seruca R

Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation. BMC cancer 14: 182, 2014. [Article] 

 doi: 10.1186/1471-2407-14-182 PMID: 24628919.

 

3. Velho S, Haigis KM

Regulation of homeostasis and oncogenesis in the intestinal epithelium by Ras Experimental cell research  1, 2011. [Review] 

 PMID: 21741971.

 

4. Velho S, Oliveira C, Paredes J, Sousa S, Leite M, Matos P, Milanezi F, Ribeiro AS, Mendes N, Licastro D, Karhu A, Oliveira MJ, Ligtenberg M, Hamelin R, Carneiro F, Lindblom A, Peltomaki P, Castedo S, Schwartz S, Jordan P, Aaltonen LA, Hofstra RM, Suriano G, Stupka E, Fialho AM, Seruca R

Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours. Human molecular genetics 19: 697-706, 2010. [Article] 

 doi: 10.1093/hmg/ddp536 PMID: 19955118.

 

5. Velho S, Corso G, Oliveíra C, Seruca R

KRAS signaling pathway alterations in microsatellite unstable gastrointestinal cancers. Advances in cancer research 109: 123-43, 2010. [Review; Book Chapter] 

 doi: 10.1016/B978-0-12-380890-5.00004-1 PMID: 21070916.

 

6. Velho S, Oliveira C, Seruca R

KRAS mutations and anti-epidermal growth factor receptor therapy in colorectal cancer with lymph node metastases. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27: 158-9; author reply 159, 2009. [Letter] 

 doi: 10.1200/JCO.2008.20.1525 PMID: 19047277.

 

7. Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis? BMC cancer 8: 255, 2008. [Article] 

 doi: 10.1186/1471-2407-8-255 PMID: 18782444.

 

8. Velho S, Oliveira C, Ferreira A, Ferreira AC, Suriano G, Schwartz S, Duval A, Carneiro F, Machado JC, Hamelin R, Seruca R

The prevalence of PIK3CA mutations in gastric and colon cancer. European journal of cancer (Oxford, England : 1990) 41: 1649-54, 2005. [Article] 

 doi: 10.1016/j.ejca.2005.04.022 PMID: 15994075.

 

1. Dias Carvalho P, Martins F, Mendonça S, Ribeiro A, Machado AL, Carvalho J, Oliveira MJ, Velho S

Mutant KRAS modulates colorectal cancer cells invasive response to fibroblast-secreted factors through the HGF/C-MET axis. International journal of cancer 151: 1810-1823, 2022. [Article] 

 doi: 10.1002/ijc.34225 PMID: 35869872.

 

2. Dias Carvalho P, Martins F, Carvalho J, Oliveira MJ, Velho S

Mutant KRAS-Associated Proteome Is Mainly Controlled by Exogenous Factors. Cells 11: ., 2022. [Article] 

 doi: 10.3390/cells11131988 PMID: 35805073.

 

3. Dias Carvalho P, Mendonça S, Martins F, Oliveira MJ, Velho S

Modulation of Fibroblast Phenotype by Colorectal Cancer Cell-Secreted Factors Is Mostly Independent of Oncogenic KRAS. Cells 11: ., 2022. [Article] 

 doi: 10.3390/cells11162490 PMID: 36010567.

 

4. Mendes N, Dias Carvalho P, Martins F, Mendonça S, Malheiro AR, Ribeiro A, Carvalho J, Velho S

Animal Models to Study Cancer and Its Microenvironment. Advances in experimental medicine and biology 1219: 389-401, 2020. [Article; Book Chapter] 

 doi: 10.1007/978-3-030-34025-4_20 PMID: 32130710.

 

5. Dias Carvalho P, Machado AL, Martins F, Seruca R, Velho S

Targeting the Tumor Microenvironment: An Unexplored Strategy for Mutant KRAS Tumors. Cancers 11: ., 2019. [Review] 

 doi: 10.3390/cancers11122010 PMID: 31847096.

 

6. Dias Carvalho P, Guimarães CF, Cardoso AP, Mendonça S, Costa ÂM, Oliveira MJ, Velho S

KRAS Oncogenic Signaling Extends beyond Cancer Cells to Orchestrate the Microenvironment. Cancer research 78: 7-14, 2018. [Review] 

 doi: 10.1158/0008-5472.CAN-17-2084 PMID: 29263151.