1. Sousa N, Fautino C, Aguas LMN, Freire J, Coutinho C, Fautino I, Capela A, Costa T, Costa ASA, Coelho S, Pereira F, Abreu SC, Rolo AS, Albergaria A, Lima J, Wen XG, Mesquita C, Dias CC, Azevedo LF, Carneiro F

Homologous recombination deficiency as prognostic marker in metastatic gastric cancer. Journal of Clinical Oncology 37: ., 2019.  [Meeting Abstract] 

 doi: 10.1200/JCO.2019.37.15_suppl.4040.

 

2. Melo M, da Rocha AG, Vinagre J, Sobrinho-Simões M, Soares P

Coexistence of TERT Promoter and BRAF Mutations in Papillary Thyroid Carcinoma: Added Value in Patient Prognosis? Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33: 667-8, 2015.  [Letter] 

 doi: 10.1200/JCO.2014.59.4614 PMID: 25605839.

 

3. Perestrelo T, Correia M, Ramalho-Santos J, Wirtz D

Metabolic and Mechanical Cues Regulating Pluripotent Stem Cell Fate. Trends in cell biology 28: 1014-1029, 2018.  [Review] 

 doi: 10.1016/j.tcb.2018.09.005 PMID: 30361056.

 

4. Boaventura P, Soares P, Pereira D, Teixeira-Gomes J, Sobrinho-Simões M

Head and neck lesions in a cohort irradiated in childhood for tinea capitis treatment. The Lancet infectious diseases 11: 163-4, 2011.  [Letter] 

 doi: 10.1016/S1473-3099(11)70047-0 PMID: 21371653.

 

5. Figueiredo C, Machado JC, Pharoah P, Seruca R, Sousa S, Carvalho R, Capelinha AF, Quint W, Caldas C, van Doorn LJ, Carneiro F, Sobrinho-Simões M

Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. Journal of the National Cancer Institute 94: 1680-7, 2002.  [Article] 

 PMID: 12441323.

 

6. Machado JC, Pharoah P, Sousa S, Carvalho R, Oliveira C, Figueiredo C, Amorim A, Seruca R, Caldas C, Carneiro F, Sobrinho-Simões M

Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology 121: 823-9, 2001.  [Article] 

 PMID: 11606496.

 

7. Machado JC, Figueiredo C, Canedo P, Pharoah P, Carvalho R, Nabais S, Castro Alves C, Campos ML, Van Doorn LJ, Caldas C, Seruca R, Carneiro F, Sobrinho-Simões M

A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125: 364-71, 2003.  [Article] 

 PMID: 12891537.

 

8. Thorstensen L, Holm R, Lothe RA, Tropé C, Carvalho B, Sobrinho-Simoes M, Seruca R

WNT-inducible signaling pathway protein 3, WISP-3, is mutated in microsatellite unstable gastrointestinal carcinomas but not in endometrial carcinomas. Gastroenterology 124: 270-1, 2003.  [Letter] 

 doi: 10.1053/gast.2003.50034 PMID: 12512062.

 

9. Pereira L, Freitas F, Fernandes V, Pereira JB, Costa MD, Costa S, Máximo V, Macaulay V, Rocha R, Samuels DC

The diversity present in 5140 human mitochondrial genomes. American journal of human genetics 84: 628-40, 2009.  [Article] 

 doi: 10.1016/j.ajhg.2009.04.013 PMID: 19426953.

 

10. Máximo V, Soares P, Machado JC, Seruca R, Sobrinho-Simões M

Mitochondrial DNA alteration in gastric cancer. Gastroenterology 119: 1808-9, 2000.  [Letter] 

 PMID: 11187439.

 

11. Pópulo H, Lopes JM, Sobrinho-Simões M, Soares P

RE: TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma. Journal of the National Cancer Institute 107: 1, 2015.  [Letter] 

 doi: 10.1093/jnci/djv049 PMID: 25755155.

 

12. Vinagre J, Almeida A, Pópulo H, Batista R, Lyra J, Pinto V, Coelho R, Celestino R, Prazeres H, Lima L, Melo M, Rocha AG, Preto A, Castro P, Castro L, Pardal F, Lopes JM, Santos LL, Reis RM, Cameselle-Teijeiro J, Sobrinho-Simões M, Lima J, Máximo V, Soares P

Frequency of TERT promoter mutations in human cancers. Nature communications 4: 2185, 2013.  [Article] 

 doi: 10.1038/ncomms3185 PMID: 23887589.

 

13. Caldeira J, Simões-Correia J, Paredes J, Pinto MT, Sousa S, Corso G, Marrelli D, Roviello F, Pereira PS, Weil D, Oliveira C, Casares F, Seruca R

CPEB1, a novel gene silenced in gastric cancer: a Drosophila approach. Gut 61: 1115-23, 2012.  [Article] 

 doi: 10.1136/gutjnl-2011-300427 PMID: 22052064.

 

14. Correia M, Pinheiro P, Batista R, Soares P, Sobrinho-Simões M, Máximo V

Etiopathogenesis of oncocytomas. Seminars in cancer biology 47: 82-94, 2017.  [Review] 

 doi: 10.1016/j.semcancer.2017.06.014 PMID: 28687249.

 

15. Soares P, Sobrinho-Simões M

Cancer: Small papillary thyroid cancers--is BRAF of prognostic value? Nature reviews. Endocrinology 7: 9-10, 2011.  [Editorial Material] 

 doi: 10.1038/nrendo.2010.213 PMID: 21160471.

 

16. Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D, Bromberg JF

STAT3 negatively regulates thyroid tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America 109: E2361-70, 2012.  [Article] 

 doi: 10.1073/pnas.1201232109 PMID: 22891351.

 

17. Pitteloud N, Zhang C, Pignatelli D, Li JD, Raivio T, Cole LW, Plummer L, Jacobson-Dickman EE, Mellon PL, Zhou QY, Crowley WF

Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proceedings of the National Academy of Sciences of the United States of America 104: 17447-52, 2007.  [Article] 

 doi: 10.1073/pnas.0707173104 PMID: 17959774.

 

18. Sousa D, T Lima R, Vasconcelos H

Intercellular Transfer of Cancer Drug Resistance Traits by Extracellular Vesicles Trends in molecular medicine  595-608, 2015.  [Review] 

 doi: 10.1016/j.molmed.2015.08.002.

 

19. Pinto ML, Rios E, Silva AC, Neves SC, Caires HR, Pinto AT, Durães C, Carvalho FA, Cardoso AP, Santos NC, Barrias CC, Nascimento DS, Pinto-do-Ó P, Barbosa MA, Carneiro F, Oliveira MJ

Decellularized human colorectal cancer matrices polarize macrophages towards an anti-inflammatory phenotype promoting cancer cell invasion via CCL18. Biomaterials 124: 211-224, 2017.  [Article] 

 doi: 10.1016/j.biomaterials.2017.02.004 PMID: 28209528.

 

20. Reis CA, David L, Correa P, Carneiro F, de Bolós C, Garcia E, Mandel U, Clausen H, Sobrinho-Simões M

Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression. Cancer research 59: 1003-7, 1999.  [Article] 

 PMID: 10070955.

 

21. Cardoso AP, Pinto ML, Pinto AT, Oliveira MI, Pinto MT, Gonçalves R, Relvas JB, Figueiredo C, Seruca R, Mantovani A, Mareel M, Barbosa MA, Oliveira MJ

Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity. Oncogene 33: 2123-33, 2014.  [Article] 

 doi: 10.1038/onc.2013.154 PMID: 23644655.

 

22. Pereira MS, Maia L, Azevedo LF, Campos S, Carvalho S, Dias AM, Albergaria A, Lima J, Marcos-Pinto R, Lago P, Pinho SS

A [Glyco]biomarker that Predicts Failure to Standard Therapy in Ulcerative Colitis Patients. Journal of Crohn's & colitis 13: 39-49, 2019.  [Article] 

 doi: 10.1093/ecco-jcc/jjy139 PMID: 30239648.

 

23. Luster M, Aktolun C, Amendoeira I, Barczynski M, Bible KC, Duntas LH, Elisei R, Handkiewicz-Junak D, Hoffmann M, Jarzab B, Leenhardt L, Musholt TJ, Newbold K, Nixon IJ, Smit J, Sobrinho-Simões M, Sosa JA, Tuttle RM, Verburg FA, Wartofsky L, Führer D

European Perspective on 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: Proceedings of an Interactive International Symposium. Thyroid : official journal of the American Thyroid Association 29: 7-26, 2019.  [Article] 

 doi: 10.1089/thy.2017.0129 PMID: 30484394.

 

24. Santos LR, Durães C, Ziros PG, Pestana A, Esteves C, Neves C, Carvalho D, Bongiovanni M, Renaud CO, Chartoumpekis DV, Habeos IG, Simões MS, Soares P, Sykiotis GP

Interaction of Genetic Variations in NFE2L2 and SELENOS Modulates the Risk of Hashimoto's Thyroiditis. Thyroid : official journal of the American Thyroid Association 29: 1302-1315, 2019.  [Article] 

 doi: 10.1089/thy.2018.0480 PMID: 31426718.

 

25. Lesueur F, Corbex M, McKay JD, Lima J, Soares P, Griseri P, Burgess J, Ceccherini I, Landolfi S, Papotti M, Amorim A, Goldgar DE, Romeo G

Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid carcinoma. Journal of medical genetics 39: 260-5, 2002.  [Article] 

 PMID: 11950855.

 

26. Pinheiro H, Carvalho J, Oliveira P, Ferreira D, Pinto MT, Osório H, Licastro D, Bordeira-Carriço R, Jordan P, Lazarevic D, Sanges R, Stupka E, Huntsman D, Seruca R, Oliveira C

Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. Human molecular genetics 21: 4253-69, 2012.  [Article] 

 doi: 10.1093/hmg/dds248 PMID: 22752307.

 

27. Pertega-Gomes N, Felisbino S, Massie CE, Vizcaino JR, Coelho R, Sandi C, Simoes-Sousa S, Jurmeister S, Ramos-Montoya A, Asim M, Tran M, Oliveira E, Lobo da Cunha A, Maximo V, Baltazar F, Neal DE, Fryer LG

A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy. The Journal of pathology 236: 517-30, 2015.  [Article] 

 doi: 10.1002/path.4547 PMID: 25875424.

 

28. Carvalho A, Carmena M, Sambade C, Earnshaw WC, Wheatley SP

Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. Journal of cell science 116: 2987-98, 2003.  [Article] 

 doi: 10.1242/jcs.00612 PMID: 12783991.

 

29. Pópulo H, Boaventura P, Vinagre J, Batista R, Mendes A, Caldas R, Pardal J, Azevedo F, Honavar M, Guimarães I, Manuel Lopes J, Sobrinho-Simões M, Soares P

TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation. The Journal of investigative dermatology 134: 2251-7, 2014.  [Article] 

 doi: 10.1038/jid.2014.163 PMID: 24691053.

 

30. Duarte TL, Caldas C, Santos AG, Silva-Gomes S, Santos-Gonçalves A, Martins MJ, Porto G, Lopes JM

Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis. Redox biology 11: 157-169, 2017.  [Article] 

 doi: 10.1016/j.redox.2016.11.013 PMID: 27936457.

 

31. Campos MA, Macedo S, Fernandes M, Pestana A, Pardal J, Batista R, Vinagre J, Sanches A, Baptista A, Lopes JM, Soares P

TERT promoter mutations are associated with poor prognosis in cutaneous squamous cell carcinoma. Journal of the American Academy of Dermatology 80: 660-669.e6, 2019.  [Article] 

 doi: 10.1016/j.jaad.2018.08.032 PMID: 30165166.

 

32. Reis RM, Könü-Lebleblicioglu D, Lopes JM, Kleihues P, Ohgaki H

Genetic profile of gliosarcomas. The American journal of pathology 156: 425-32, 2000.  [Article] 

 PMID: 10666371.

 

33. Brüggemann M, White H, Gaulard P, Garcia-Sanz R, Gameiro P, Oeschger S, Jasani B, Ott M, Delsol G, Orfao A, Tiemann M, Herbst H, Langerak AW, Spaargaren M, Moreau E, Groenen PJ, Sambade C, Foroni L, Carter GI, Hummel M, Bastard C, Davi F, Delfau-Larue MH, Kneba M, van Dongen JJ, Beldjord K, Molina TJ

Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936. Leukemia 21: 215-21, 2007.  [Article] 

 doi: 10.1038/sj.leu.2404481 PMID: 17170730.

 

34. Zainol M, Stoute J, Almeida GM, Rapp A, Bowman KJ, Jones GD,

Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair. Nucleic acids research 37: e150, 2009.  [Article] 

 doi: 10.1093/nar/gkp826 PMID: 19828597.

 

35. Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene 24: 7630-4, 2005.  [Article] 

 doi: 10.1038/sj.onc.1208906 PMID: 16007118.

 

36. Máximo V, Soares P, Lima J, Cameselle-Teijeiro J, Sobrinho-Simões M

Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors. The American journal of pathology 160: 1857-65, 2002.  [Article] 

 PMID: 12000737.

 

37. Machado AM, Figueiredo C, Touati E, Máximo V, Sousa S, Michel V, Carneiro F, Nielsen FC, Seruca R, Rasmussen LJ

Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells. Clinical cancer research : an official journal of the American Association for Cancer Research 15: 2995-3002, 2009.  [Article] 

 doi: 10.1158/1078-0432.CCR-08-2686 PMID: 19383819.

 

38. Machado JC, Oliveira C, Carvalho R, Soares P, Berx G, Caldas C, Seruca R, Carneiro F, Sobrinho-Simöes M

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma. Oncogene 20: 1525-8, 2001.  [Article] 

 doi: 10.1038/sj.onc.1204234 PMID: 11313896.

 

39. Moniz S, Martinho O, Pinto F, Sousa B, Loureiro C, Oliveira MJ, Moita LF, Honavar M, Pinheiro C, Pires M, Lopes JM, Jones C, Costello JF, Paredes J, Reis RM, Jordan P

Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness. Human molecular genetics 22: 84-95, 2013.  [Article] 

 doi: 10.1093/hmg/dds405 PMID: 23035050.

 

40. Albuquerque A, Rios E, Dias CC, Nathan M

p16 immunostaining in histological grading of anal squamous intraepithelial lesions: a systematic review and meta-analysis. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 31: 1026-1035, 2018.  [Review] 

 doi: 10.1038/s41379-018-0026-6 PMID: 29434342.

 

41. Lopes R, Castro I, Pontes P, Candeias J, Lemoine NR, Sambade C

Expression profile of survivin in acute leukaemias: the importance of differential splicing. Leukemia 19: 1284-6, 2005.  [Letter] 

 doi: 10.1038/sj.leu.2403765 PMID: 15843822.

 

42. Castro P, Soares P, Gusmão L, Seruca R, Sobrinho-Simões M

H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid. Oncogene 25: 4620-7, 2006.  [Article] 

 doi: 10.1038/sj.onc.1209491 PMID: 16532025.

 

43. Batista R, Cruvinel-Carloni A, Vinagre J, Peixoto J, Catarino TA, Campanella NC, Menezes W, Becker AP, de Almeida GC, Matsushita MM, Clara C, Neder L, Viana-Pereira M, Honavar M, Castro L, Lopes JM, Carvalho B, Vaz RM, Máximo V, Soares P, Sobrinho-Simões M, Reis RM, Lima J

The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism. International journal of cancer 139: 414-23, 2016.  [Article] 

 doi: 10.1002/ijc.30057 PMID: 26914704.

 

44. Soares P, Trovisco V, Rocha AS, Lima J, Castro P, Preto A, Máximo V, Botelho T, Seruca R, Sobrinho-Simões M

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene 22: 4578-80, 2003.  [Article] 

 doi: 10.1038/sj.onc.1206706 PMID: 12881714.

 

45. Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S, Carneiro F, Seruca R

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene 26: 158-63, 2007.  [Article] 

 doi: 10.1038/sj.onc.1209758 PMID: 16953233.

 

46. Faustino A, Couto JP, Pópulo H, Rocha AS, Pardal F, Cameselle-Teijeiro JM, Lopes JM, Sobrinho-Simões M, Soares P

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism 97: E1139-49, 2012.  [Article] 

 doi: 10.1210/jc.2011-2748 PMID: 22549934.

 

47. Prazeres H, Torres J, Rodrigues F, Pinto M, Pastoriza MC, Gomes D, Cameselle-Teijeiro J, Vidal A, Martins TC, Sobrinho-Simões M, Soares P

Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells. Oncogene 30: 1302-17, 2011.  [Article] 

 doi: 10.1038/onc.2010.512 PMID: 21057533.

 

48. Sigstad E, Paus E, Bjøro T, Berner A, Grøholt KK, Jørgensen LH, Sobrinho-Simões M, Holm R, Warren DJ

Reply to 'The new molecular markers DDIT3, STT3A, ARG2 and FAM129A are not useful in diagnosing thyroid follicular tumors'. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 26: 613-5, 2013.  [Letter] 

 doi: 10.1038/modpathol.2013.39 PMID: 23542526.

 

49. Cole LW, Sidis Y, Zhang C, Quinton R, Plummer L, Pignatelli D, Hughes VA, Dwyer AA, Raivio T, Hayes FJ, Seminara SB, Huot C, Alos N, Speiser P, Takeshita A, Van Vliet G, Pearce S, Crowley WF, Zhou QY, Pitteloud N

Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum. The Journal of clinical endocrinology and metabolism 93: 3551-9, 2008.  [Article] 

 doi: 10.1210/jc.2007-2654 PMID: 18559922.

 

50. Preto A, Singhrao SK, Haughton MF, Kipling D, Wynford-Thomas D, Jones CJ

Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy. Oncogene 23: 4136-45, 2004.  [Article] 

 doi: 10.1038/sj.onc.1207564 PMID: 15064743.

 

51. Melo M, Costa G, Ribeiro C, Carrilho F, Martins MJ, da Rocha AG, Sobrinho-Simões M, Carvalheiro M, Soares P

Stimulated Thyroglobulin at Recombinant Human TSH-Aided Ablation Predicts Disease-free Status One Year Later. The Journal of clinical endocrinology and metabolism 98: 4364-72, 2013.  [Article] 

 doi: 10.1210/jc.2013-2267 PMID: 24037891.

 

52. Ziros PG, Manolakou SD, Habeos IG, Lilis I, Chartoumpekis DV, Koika V, Soares P, Kyriazopoulou VE, Scopa CD, Papachristou DJ, Sykiotis GP

Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells. The Journal of clinical endocrinology and metabolism 98: E1422-7, 2013.  [Article] 

 doi: 10.1210/jc.2013-1510 PMID: 23766517.

 

53. Costa BM, Ferreira P, Costa S, Canedo P, Oliveira P, Silva A, Pardal F, Suriano G, Machado JC, Lopes JM, Reis RM

Association between functional EGF+61 polymorphism and glioma risk. Clinical cancer research : an official journal of the American Association for Cancer Research 13: 2621-6, 2007.  [Article] 

 doi: 10.1158/1078-0432.CCR-06-2606 PMID: 17473192.

 

54. Castro P, Eknaes M, Teixeira MR, Danielsen HE, Soares P, Lothe RA, Sobrinho-Simões M

Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes. The Journal of pathology 206: 305-11, 2005.  [Article] 

 doi: 10.1002/path.1772 PMID: 15852498.

 

55. Melo M, da Rocha AG, Vinagre J, Batista R, Peixoto J, Tavares C, Celestino R, Almeida A, Salgado C, Eloy C, Castro P, Prazeres H, Lima J, Amaro T, Lobo C, Martins MJ, Moura M, Cavaco B, Leite V, Cameselle-Teijeiro JM, Carrilho F, Carvalheiro M, Máximo V, Sobrinho-Simões M, Soares P

TERT Promoter Mutations Are a Major Indicator of Poor Outcome in Differentiated Thyroid Carcinomas. The Journal of clinical endocrinology and metabolism 99: E754-65, 2014.  [Article] 

 doi: 10.1210/jc.2013-3734 PMID: 24476079.

 

56. Santos LR, Durães C, Mendes A, Prazeres H, Alvelos MI, Moreira CS, Canedo P, Esteves C, Neves C, Carvalho D, Sobrinho-Simões M, Soares P

A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility. The Journal of clinical endocrinology and metabolism 99: E719-23, 2014.  [Article] 

 doi: 10.1210/jc.2013-3539 PMID: 24471570.

 

57. Albuquerque A, Rios E, Schmitt F

Recommendations Favoring Anal Cytology as a Method for Anal Cancer Screening: A Systematic Review. Cancers 11: ., 2019.  [Review] 

 doi: 10.3390/cancers11121942 PMID: 31817212.

 

58. Nunes JB, Peixoto J, Soares P, Maximo V, Carvalho S, Pinho SS, Vieira AF, Paredes J, Rego AC, Ferreira IL, Gomez-Lazaro M, Sobrinho-Simoes M, Singh KK, Lima J

OXPHOS dysfunction regulates integrin-ß1 modifications and enhances cell motility and migration. Human molecular genetics 24: 1977-90, 2015.  [Article] 

 doi: 10.1093/hmg/ddu612 PMID: 25504047.

 

59. Cameselle-Teijeiro JM, Rodríguez-Pérez I, Celestino R, Eloy C, Piso-Neira M, Abdulkader-Nallib I, Soares P, Sobrinho-Simões M

Hobnail Variant of Papillary Thyroid Carcinoma: Clinicopathologic and Molecular Evidence of Progression to Undifferentiated Carcinoma in 2 Cases. The American journal of surgical pathology 41: 854-860, 2017.  [Article] 

 doi: 10.1097/PAS.0000000000000793 PMID: 28009606.

 

60. Lima J, Teixeira-Gomes J, Soares P, Máximo V, Honavar M, Williams D, Sobrinho-Simões M

Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia. The Journal of clinical endocrinology and metabolism 88: 4932-7, 2003.  [Article] 

 PMID: 14557476.

 

61. da Silva AF, Mariotti FR, Máximo V, Campello S

Mitochondria dynamism: of shape, transport and cell migration. Cellular and molecular life sciences : CMLS 71: 2313-24, 2014.  [Review] 

 doi: 10.1007/s00018-014-1557-8 PMID: 24442478.

 

62. Castro P, Vieira de Castro I, Rebocho AP, Soares RJ, Magalhães J, Roque L, Trovisco V, Cardoso-de-Oliveira M, Fonseca E, Soares P, Sobrinho-Simões M

PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism 91: 213-20, 2006.  [Article] 

 doi: 10.1210/jc.2005-1336 PMID: 16219715.

 

63. Melo M, Gaspar da Rocha A, Batista R, Vinagre J, Martins MJ, Costa G, Ribeiro C, Carrilho F, Leite V, Lobo C, Cameselle-Teijeiro JM, Cavadas B, Pereira L, Sobrinho-Simões M, Soares P

TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease. The Journal of clinical endocrinology and metabolism 102: 1898-1907, 2017.  [Article] 

 doi: 10.1210/jc.2016-2785 PMID: 28323937.

 

64. Lima J, Trovisco V, Soares P, Máximo V, Magalhães J, Salvatore G, Santoro M, Bogdanova T, Tronko M, Abrosimov A, Jeremiah S, Thomas G, Williams D, Sobrinho-Simões M

BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomas. The Journal of clinical endocrinology and metabolism 89: 4267-71, 2004.  [Article] 

 doi: 10.1210/jc.2003-032224 PMID: 15356020.

 

65. Grigg J, Tellabati A, Rhead S, Almeida GM, Higgins JA, Bowman KJ, Jones GD, Howes PB

DNA damage of macrophages at an air-tissue interface induced by metal nanoparticles Nanotoxicology 3: 348-354, 2009.  [Article] 

 doi: 10.3109/17435390903276917.

 

66. Rocha AS, Paternot S, Coulonval K, Dumont JE, Soares P, Roger PP

Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation. Molecular biology of the cell 19: 4814-25, 2008.  [Article] 

 doi: 10.1091/mbc.E08-06-0617 PMID: 18799615.

 

67. Gonçalves AP, Máximo V, Lima J, Singh KK, Soares P, Videira A

Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH  1813: 492-9, 2011.  [Article] 

 doi: 10.1016/j.bbamcr.2011.01.006 PMID: 21223980.

 

68. Lima J, Feijão T, Ferreira da Silva A, Pereira-Castro I, Fernandez-Ballester G, Máximo V, Herrero A, Serrano L, Sobrinho-Simões M, Garcia-Rostan G

High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations. The Journal of clinical endocrinology and metabolism 92: 4853-64, 2007.  [Article] 

 doi: 10.1210/jc.2007-0640 PMID: 17848412.

 

69. Shi X, Liu R, Basolo F, Giannini R, Shen X, Teng D, Guan H, Shan Z, Teng W, Musholt TJ, Al-Kuraya K, Fugazzola L, Colombo C, Kebebew E, Jarzab B, Czarniecka A, Bendlova B, Sykorova V, Sobrinho-Simões M, Soares P, Shong YK, Kim TY, Cheng S, Asa SL, Viola D, Elisei R, Yip L, Mian C, Vianello F, Wang Y, Zhao S, Oler G, Cerutti JM, Puxeddu E, Qu S, Wei Q, Xu H, O'Neill CJ, Sywak MS, Clifton-Bligh R, Lam AK, Riesco-Eizaguirre G, Santisteban P, Yu H, Tallini G, Holt EH, Vasko V, Xing M

Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants. The Journal of clinical endocrinology and metabolism 101: 264-74, 2016.  [Article] 

 doi: 10.1210/jc.2015-2917 PMID: 26529630.

 

70. Bartosch C, Pires-Luís AS, Meireles C, Baptista M, Gouveia A, Pinto C, Shannon KM, Jerónimo C, Teixeira MR, Lopes JM, Oliva E

Pathologic Findings in Prophylactic and Nonprophylactic Hysterectomy Specimens of Patients With Lynch Syndrome. The American journal of surgical pathology 40: 1177-91, 2016.  [Article] 

 doi: 10.1097/PAS.0000000000000684 PMID: 27340747.

 

71. Trovisco V, Vieira de Castro I, Soares P, Máximo V, Silva P, Magalhães J, Abrosimov A, Guiu XM, Sobrinho-Simões M

BRAF mutations are associated with some histological types of papillary thyroid carcinoma. The Journal of pathology 202: 247-51, 2004.  [Article] 

 doi: 10.1002/path.1511 PMID: 14743508.

 

72. Carneiro F, Huntsman DG, Smyrk TC, Owen DA, Seruca R, Pharoah P, Caldas C, Sobrinho-Simões M

Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. The Journal of pathology 203: 681-7, 2004.  [Article] 

 doi: 10.1002/path.1564 PMID: 15141383.

 

73. Amendoeira I, Maia T, Sobrinho-Simões M

Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): impact on the reclassification of thyroid nodules. Endocrine-related cancer 25: R247-R258, 2018.  [Review] 

 doi: 10.1530/ERC-17-0513 PMID: 29439059.

 

74. Máximo V, Lima J, Prazeres H, Soares P, Sobrinho-Simões M

The biology and the genetics of Hurthle cell tumors of the thyroid. Endocrine-related cancer 19: R131-47, 2012.  [Review] 

 doi: 10.1530/ERC-11-0354 PMID: 22514109.

 

75. Sigstad E, Paus E, Bjøro T, Berner A, Grøholt KK, Jørgensen LH, Sobrinho-Simões M, Holm R, Warren DJ

The new molecular markers DDIT3, STT3A, ARG2 and FAM129A are not useful in diagnosing thyroid follicular tumors. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 25: 537-47, 2012.  [Article] 

 doi: 10.1038/modpathol.2011.188 PMID: 22157935.

 

76. Bartosch C, Monteiro-Reis S, Almeida-Rios D, Vieira R, Castro A, Moutinho M, Rodrigues M, Graça I, Lopes JM, Jerónimo C

Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium. Oncotarget 7: 1144-54, 2016.  [Article] 

 doi: 10.18632/oncotarget.6691 PMID: 26701732.

 

77. Ferreira LB, Tavares C, Pestana A, Pereira CL, Eloy C, Pinto MT, Castro P, Batista R, Rios E, Sobrinho-Simões M, Gimba ER, Soares P

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior. Oncotarget 7: 52003-52016, 2016.  [Article] 

 doi: 10.18632/oncotarget.10468 PMID: 27409830.

 

78. Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. The Journal of pathology 214: 320-7, 2008.  [Article] 

 doi: 10.1002/path.2295 PMID: 18098337.

 

79. Davi F, Sambade C, Garcia-Sanz R, Colin C, Hercher H, Gonzalez D, Nireuay F, Diss TC, Evans PAS, Flohr TM, Molina TJ

Section 4: IGL gene rearrangements. Leukemia 17: 2280-2289, 2003.  [] 

.

 

80. Langerak AW, Moreau E, Swczepanski T, Oud NECM, Raaphorst FM, Groenen PJTA, Gonzalez D, Sambade C, Mills KI, Carter GI, Bruggemann M, Beldjord K, Macintyre EA, Bassegio I, Garcia JF, van Dongen JJM

Section 2: Incomplete IGH gene rearrangements DH-JH. Leukemia 17: 2272-2275, 2003.  [] 

.

 

81. Rocha AS, Soares P, Seruca R, Máximo V, Matias-Guiu X, Cameselle-Teijeiro J, Sobrinho-Simões M

Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant. The Journal of pathology 194: 358-66, 2001.  [Article] 

 doi: 10.1002/path.905 PMID: 11439369.

 

82. Nabais S, Carneiro F, Nogueira AM, Machado JC, Seruca R, Sobrinho-Simões M

Re. 'Cellular phenotypes of differentiated-type adenocarcinomas and precancerous lesions of the stomach are dependent on the genetic pathways'. The Journal of pathology 195: 636-7, 2001.  [Letter] 

 doi: 10.1002/path.958 PMID: 11745702.

 

83. Pinto F, Martinho O, Moniz S, Jones C, Lopes JM, Honovan H, Pires M, Jordan P, Reis M

295 Protein Kinase WNK2 Was Correlated With Poor Outcome and Malignant Behavior in Glioma Cell Lines European journal of cancer (Oxford, England : 1990)  S72, 2012.  [] 

 doi: 10.1016/S0959-8049(12)70989-9.

 

84. Pópulo H, Soares P, Faustino A, Rocha AS, Silva P, Azevedo F, Lopes JM

mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics. Pigment cell & melanoma research 24: 254-7, 2011.  [Letter] 

 doi: 10.1111/j.1755-148X.2010.00796.x PMID: 21029395.

 

85. Pojo M, Gonçalves CS, Xavier-Magalhães A, Oliveira AI, Gonçalves T, Correia S, Rodrigues AJ, Costa S, Pinto L, Pinto AA, Lopes JM, Reis RM, Rocha M, Sousa N, Costa BM

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. Oncotarget 6: 7657-74, 2015.  [Article] 

 PMID: 25762636.

 

86. Leão R, Lee D, Figueiredo A, Hermanns T, Wild P, Komosa M, Lau I, Mistry M, Nunes NM, Price AJ, Zhang C, Lipman T, Poyet C, Valtcheva N, Oehl K, Coelho H, Sayyid R, Gomes AM, Prado E Castro L, Sweet J, Vinagre J, Apolónio J, Stephens D, Faleiro I, Fadaak K, Richard PO, Kulkarni G, Zlotta AR, Hamilton RJ, Castelo-Branco P, Tabori U

Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer. International journal of cancer 144: 1676-1684, 2019.  [Article] 

 doi: 10.1002/ijc.31935 PMID: 30350309.

 

87. Bartosch C, Lopes JM, Jerónimo C

Epigenetics in endometrial carcinogenesis - part 2: histone modifications, chromatin remodeling and noncoding RNAs. Epigenomics 9: 873-892, 2017.  [Review] 

 doi: 10.2217/epi-2016-0167 PMID: 28523964.

 

88. Bartosch C, Lopes JM, Jerónimo C

Epigenetics in endometrial carcinogenesis - part 1: DNA methylation. Epigenomics 9: 737-755, 2017.  [Review] 

 doi: 10.2217/epi-2016-0166 PMID: 28470096.

 

89. Ferreira AC, Gomes L, Máximo V, Amil J, Carneiro F, Machado JC, Tavarela-Veloso F

GRIM-19 mutations are not associated with Crohn's disease. Inflammatory bowel diseases 14: 434-5, 2008.  [Letter] 

 doi: 10.1002/ibd.20313 PMID: 18022871.

 

90. Seca H, Almeida GM, Guimarães JE, Vasconcelos MH

miR signatures and the role of miRs in acute myeloid leukaemia. European journal of cancer (Oxford, England : 1990) 46: 1520-1527, 2010.  [Review] 

 doi: 10.1016/j.ejca.2010.03.031 PMID: 20413298.

 

91. Martins RG, Nunes JB, Máximo V, Soares P, Peixoto J, Catarino T, Rito T, Soares P, Pereira L, Sobrinho-Simões M, Santos AP, Couto J, Henrique R, Matos-Loureiro J, Dias P, Torres I, Lima J

A founder SDHB mutation in Portuguese paraganglioma patients. Endocrine-related cancer 20: L23-6, 2013.  [Letter] 

 doi: 10.1530/ERC-12-0399 PMID: 24092654.

 

92. Huang H, Reis R, Yonekawa Y, Lopes JM, Kleihues P, Ohgaki H

Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain pathology (Zurich, Switzerland) 9: 33-42, 1999.  [Article] 

 PMID: 9989448.

 

93. Pópulo H, Caldas R, Lopes JM, Pardal J, Máximo V, Soares P

Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy. Expert opinion on therapeutic targets 19: 733-45, 2015.  [Article] 

 doi: 10.1517/14728222.2015.1045416 PMID: 25976231.

 

94. Sobrinho-Simões M, Eloy C, Magalhães J, Lobo C, Amaro T

Follicular thyroid carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 24 Suppl 2: S10-8, 2011.  [Article] 

 doi: 10.1038/modpathol.2010.133 PMID: 21455197.

 

95. Flores C, Lima RT, Adessi A, Sousa A, Pereira SB, Granja PL, De Philippis R, Soares P, Tamagnini P

Characterization and antitumor activity of the extracellular carbohydrate polymer from the cyanobacterium Synechocystis ¿sigF mutant. International journal of biological macromolecules 136: 1219-1227, 2019.  [Article] 

 doi: 10.1016/j.ijbiomac.2019.06.152 PMID: 31233798.

 

96. Pinto ML, Rios E, Durães C, Ribeiro R, Machado JC, Mantovani A, Barbosa MA, Carneiro F, Oliveira MJ

The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer. Frontiers in immunology 10: 1875, 2019.  [Article] 

 doi: 10.3389/fimmu.2019.01875 PMID: 31481956.

 

97. Martins S, Trigo F, Azevedo L, Silva MJ, Guimaraes JE, Amorim A

Haplotype study of microsatellites flanking the t(15;17) breakpoint in acute promyelocytic leukemia patients from North Portugal. Leukemia 16: 1353-7, 2002.  [Article] 

 doi: 10.1038/sj.leu.2402525 PMID: 12094260.

 

98. Lloyd RV, Erickson LA, Casey MB, Lam KY, Lohse CM, Asa SL, Chan JK, DeLellis RA, Harach HR, Kakudo K, LiVolsi VA, Rosai J, Sebo TJ, Sobrinho-Simoes M, Wenig BM, Lae ME

Observer variation in the diagnosis of follicular variant of papillary thyroid carcinoma. The American journal of surgical pathology 28: 1336-40, 2004.  [Article] 

 PMID: 15371949.

 

99. Lima J, Máximo V, Soares P, Williams D, Bogdanova T, Thomas GA, Sobrinho-Simões M

Re: Lohrer,H.D., Hieber,L. and Zitzelsberger,H. (2002) Differential mutation frequency in mitochondrial DNA from thyroid tumours. Carcinogenesis, 23, 1577-1582. Carcinogenesis 24: 1155, 2003.  [Letter] 

 doi: 10.1093/carcin/bgg050 PMID: 12807747.

 

100. David L, Silva F, Seruca R, Pinto M, Reis C, Sobrinho-Simões M

Correspondence re: A. E. Biemer-Huttmann et al., Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin. Cancer Res., 6: 1909-1916, 2000. Clinical cancer research : an official journal of the American Association for Cancer Research 6: 4461-2, 2000.  [Letter] 

 PMID: 11106267.

 

101. Campanella NC, Celestino R, Pestana A, Scapulatempo-Neto C, de Oliveira AT, Brito MJ, Gouveia A, Lopes JM, Guimarães DP, Soares P, Reis RM

Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs). European journal of human genetics : EJHG 23: 877-9, 2015.  [Article] 

 doi: 10.1038/ejhg.2014.195 PMID: 25248398.

 

102. Teixeira A, David L, Reis CA, Costa J, Sobrinho-Simões M

Expression of mucins (MUC1, MUC2, MUC5AC, and MUC6) and type 1 Lewis antigens in cases with and without Helicobacter pylori colonization in metaplastic glands of the human stomach. The Journal of pathology 197: 37-43, 2002.  [Article] 

 doi: 10.1002/path.1083 PMID: 12081201.

 

103. Koos B, Kamali-Moghaddam M, David L, Sobrinho-Simões M, Dimberg A, Nilsson M, Wählby C, Söderberg O

Next-generation pathology--surveillance of tumor microecology. Journal of molecular biology 427: 2013-22, 2015.  [Review] 

 doi: 10.1016/j.jmb.2015.02.017 PMID: 25725260.

 

104. Lado-Abeal J, Celestino R, Bravo SB, Garcia-Rendueles ME, de la Calzada J, Castro I, Castro P, Espadinha C, Palos F, Soares P, Alvarez CV, Sobrinho-Simões M, Cameselle-Teijeiro J

Identification of a paired box gene 8-peroxisome proliferator-activated receptor gamma (PAX8-PPARgamma) rearrangement mosaicism in a patient with an autonomous functioning follicular thyroid carcinoma bearing an activating mutation in the TSH receptor. Endocrine-related cancer 17: 599-610, 2010.  [Article] 

 doi: 10.1677/ERC-09-0069 PMID: 20427420.

 

105. Máximo V, Soares P, Seruca R, Rocha AS, Castro P, Sobrinho-Simões M

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma. Genes, chromosomes & cancer 32: 136-43, 2001.  [Article] 

 PMID: 11550281.

 

106. Peixoto J, Lima J

Metabolic traits of cancer stem cells. Disease models & mechanisms 11: ., 2018.  [Review] 

 doi: 10.1242/dmm.033464 PMID: 29991569.

 

107. Prazeres H, Couto JP, Rodrigues F, Vinagre J, Torres J, Trovisco V, Martins TC, Sobrinho-Simões M, Soares P

In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp. Endocrine-related cancer 18: 401-12, 2011.  [Article] 

 doi: 10.1530/ERC-10-0258 PMID: 21551259.

 

108. Andrade MN, Santos-Silva AP, Rodrigues-Pereira P, Paiva-Melo FD, de Lima Junior NC, Teixeira MP, Soares P, Dias GRM, Graceli JB, de Carvalho DP, Ferreira ACF, Miranda-Alves L

The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats. Environmental pollution (Barking, Essex : 1987) 241: 636-645, 2018.  [Article] 

 doi: 10.1016/j.envpol.2018.06.006 PMID: 29902746.

 

109. Boaventura P, Bastos J, Pereira D, Soares P, Teixeira-Gomes JM

Alopecia in women submitted to childhood X-ray epilation for tinea capitis treatment. The British journal of dermatology 163: 643-4, 2010.  [Letter] 

 doi: 10.1111/j.1365-2133.2010.09846.x PMID: 20456347.

 

110. Martinho O, Longatto-Filho A, Lambros MB, Martins A, Pinheiro C, Silva A, Pardal F, Amorim J, Mackay A, Milanezi F, Tamber N, Fenwick K, Ashworth A, Reis-Filho JS, Lopes JM, Reis RM

Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. British journal of cancer 101: 973-82, 2009.  [Article] 

 doi: 10.1038/sj.bjc.6605225 PMID: 19707201.

 

111. Boaventura P, Batista R, Pestana A, Reis M, Mendes A, Eloy C, Sobrinho-Simões M, Soares P

TERT promoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation. European journal of endocrinology 176: 49-55, 2017.  [Article] 

 doi: 10.1530/EJE-16-0740 PMID: 27760791.

 

112. Pereira SS, Monteiro MP, Bourdeau I, Lacroix A, Pignatelli D

MECHANISMS OF ENDOCRINOLOGY: Cell cycle regulation in adrenocortical carcinoma. European journal of endocrinology 179: R95-R110, 2018.  [Review] 

 doi: 10.1530/EJE-17-0976 PMID: 29773584.

 

113. Teresa Pinto A, Laranjeiro Pinto M, Patrícia Cardoso A, Monteiro C, Teixeira Pinto M, Filipe Maia A, Castro P, Figueira R, Monteiro A, Marques M, Mareel M, Dos Santos SG, Seruca R, Adolfo Barbosa M, Rocha S, José Oliveira M

Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities. Scientific reports 6: 18765, 2016.  [Article] 

 doi: 10.1038/srep18765 PMID: 26735768.

 

114. Vinagre J, Nabais J, Pinheiro J, Batista R, Oliveira RC, Gonçalves AP, Pestana A, Reis M, Mesquita B, Pinto V, Lyra J, Cipriano MA, Ferreira MG, Lopes JM, Sobrinho-Simões M, Soares P

TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes. Scientific reports 6: 29714, 2016.  [Article] 

 doi: 10.1038/srep29714 PMID: 27411289.

 

115. Pinto M, Soares P, Ribatti D

Thyroid hormone as a regulator of tumor induced angiogenesis. Cancer letters 301: 119-26, 2011.  [Review] 

 doi: 10.1016/j.canlet.2010.11.011 PMID: 21183275.

 

116. Celestino R, Lima J, Faustino A, Vinagre J, Máximo V, Gouveia A, Soares P, Lopes JM

Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors. European journal of human genetics : EJHG 21: 503-10, 2013.  [Article] 

 doi: 10.1038/ejhg.2012.205 PMID: 22948025.

 

117. Lima J, Máximo V, Soares P, Sobrinho-Simões M

Alterations of the SDHD gene locus in midgut carcinoids. Genes, chromosomes & cancer 36: 424, 2003.  [Letter] 

 doi: 10.1002/gcc.10147 PMID: 12619155.

 

118. Volante M, Collini P, Nikiforov YE, Sakamoto A, Kakudo K, Katoh R, Lloyd RV, LiVolsi VA, Papotti M, Sobrinho-Simoes M, Bussolati G, Rosai J

Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. The American journal of surgical pathology 31: 1256-64, 2007.  [Article] 

 doi: 10.1097/PAS.0b013e3180309e6a PMID: 17667551.

 

119. Gomes AL, Reis-Filho JS, Lopes JM, Martinho O, Lambros MB, Martins A, Schmitt F, Pardal F, Reis RM

Molecular alterations of KIT oncogene in gliomas. Cellular oncology : the official journal of the International Society for Cellular Oncology 29: 399-408, 2007.  [Article] 

 PMID: 17726262.

 

120. Pinto M, Oliveira C, Machado JC, Cirnes L, Tavares J, Carneiro F, Hamelin R, Hofstra R, Seruca R, Sobrinho-Simões M

MSI-L gastric carcinomas share the hMLH1 methylation status of MSI-H carcinomas but not their clinicopathological profile. Laboratory investigation; a journal of technical methods and pathology 80: 1915-23, 2000.  [Article] 

 PMID: 11140703.

 

121. Reis RM, Martins A, Ribeiro SA, Basto D, Longatto-Filho A, Schmitt FC, Lopes JM

Molecular characterization of PDGFR-alpha/PDGF-A and c-KIT/SCF in gliosarcomas. Cellular oncology : the official journal of the International Society for Cellular Oncology 27: 319-26, 2005.  [Article] 

 PMID: 16373964.

 

122. Machado JC, Nogueira AM, Carneiro F, Reis CA, Sobrinho-Simões M

Gastric carcinoma exhibits distinct types of cell differentiation: an immunohistochemical study of trefoil peptides (TFF1 and TFF2) and mucins (MUC1, MUC2, MUC5AC, and MUC6). The Journal of pathology 190: 437-43, 2000.  [Article] 

 doi: 10.1002/(SICI)1096-9896(200003)190:4<437::AID-PATH547>3.0.CO;2-1 PMID: 10699992.

 

123. Máximo V, Sobrinho-Simões M

Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid. The Journal of pathology 192: 561-2, 2000.  [Letter] 

 doi: 10.1002/1096-9896(200012)192:4<561::AID-PATH790>3.0.CO;2-3 PMID: 11113879.

 

124. Machado J, Carneiro F, Sobrinho-Simões M

E-cadherin mutations in gastric carcinoma. The Journal of pathology 191: 466-8, 2000.  [Letter] 

 doi: 10.1002/1096-9896(200008)191:4<466::AID-PATH626>3.0.CO;2-Q PMID: 10918224.

 

125. Pópulo H, Soares P, Lopes JM

Insights into melanoma: targeting the mTOR pathway for therapeutics. Expert opinion on therapeutic targets 16: 689-705, 2012.  [Review] 

 doi: 10.1517/14728222.2012.691472 PMID: 22620498.

 

126. Costa BM, Viana-Pereira M, Fernandes R, Costa S, Linhares P, Vaz R, Pinheiro C, Lima J, Soares P, Silva A, Pardal F, Amorim J, Nabiço R, Almeida R, Alegria C, Pires MM, Pinheiro C, Carvalho E, Oliveira P, Lopes JM, Reis RM

Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20: 2610-7, 2011.  [Article] 

 doi: 10.1158/1055-9965.EPI-11-0340 PMID: 21960689.

 

127. Máximo V, Botelho T, Capela J, Soares P, Lima J, Taveira A, Amaro T, Barbosa AP, Preto A, Harach HR, Williams D, Sobrinho-Simões M

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid. British journal of cancer 92: 1892-8, 2005.  [Article] 

 doi: 10.1038/sj.bjc.6602547 PMID: 15841082.

 

128. Tavares C, Melo M, Cameselle-Teijeiro JM, Soares P, Sobrinho-Simões M

ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome. European journal of endocrinology 174: R117-26, 2016.  [Review] 

 doi: 10.1530/EJE-15-0605 PMID: 26510840.

 

129. Ferreira LB, Eloy C, Pestana A, Lyra J, Moura M, Prazeres H, Tavares C, Sobrinho-Simões M, Gimba E, Soares P

Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma. European journal of endocrinology 174: 551-61, 2016.  [Article] 

 doi: 10.1530/EJE-15-0577 PMID: 26811408.

 

130. Alves JM, Lima AC, Pais IA, Amir N, Celestino R, Piras G, Monne M, Comas D, Heutink P, Chikhi L, Amorim A, Lopes AM

Reassessing the Evolutionary History of the 17q21 Inversion Polymorphism. Genome biology and evolution 7: 3239-3248, 2015.  [Article] 

 doi: 10.1093/gbe/evv214 PMID: 26560338.

 

131. Lyra J, Vinagre J, Batista R, Pinto V, Prazeres H, Rodrigues F, Eloy C, Sobrinho-Simões M, Soares P

mTOR activation in medullary thyroid carcinoma with RAS mutation. European journal of endocrinology 171: 633-40, 2014.  [Article] 

 doi: 10.1530/EJE-14-0389 PMID: 25163725.

 

132. Albuquerque A, Fernandes M, Stirrup O, Teixeira AL, Santos J, Rodrigues M, Rios E, Macedo G, Medeiros R

Expression of microRNAs 16, 20a, 150 and 155 in anal squamous intraepithelial lesions from high-risk groups. Scientific reports 9: 1523, 2019.  [Article] 

 doi: 10.1038/s41598-018-38378-6 PMID: 30728437.

 

133. Carvalho R, Kayademir T, Soares P, Canedo P, Sousa S, Oliveira C, Leistenschneider P, Seruca R, Gött P, Blin N, Carneiro F, Machado JC

Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma. Laboratory investigation; a journal of technical methods and pathology 82: 1319-26, 2002.  [Article] 

 PMID: 12379766.

 

134. Reis-Filho JS, Paiva ME, Lopes JM

August 2003: 47-year-old female with a 7-year history of osteomalacia and hypophosphatemia. Brain pathology (Zurich, Switzerland) 14: 111-2, 115, 2004.  [Article] 

 PMID: 14997944.

 

135. Bartosch C, Manuel Lopes J, Oliva E

Endometrial carcinomas: a review emphasizing overlapping and distinctive morphological and immunohistochemical features. Advances in anatomic pathology 18: 415-37, 2011.  [Review] 

 doi: 10.1097/PAP.0b013e318234ab18 PMID: 21993268.

 

136. Tavares C, Coelho MJ, Melo M, da Rocha AG, Pestana A, Batista R, Salgado C, Eloy C, Ferreira L, Rios E, Sobrinho-Simões M, Soares P

pmTOR is a marker of aggressiveness in papillary thyroid carcinomas. Surgery 160: 1582-1590, 2016.  [Article] 

 doi: 10.1016/j.surg.2016.06.050 PMID: 27574774.

 

137. Castro L, Alves S, Chaves SR, Costa JL, Soares P, Preto A

RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation. Molecular and cellular endocrinology 415: 64-75, 2015.  [Article] 

 doi: 10.1016/j.mce.2015.08.006 PMID: 26265449.

 

138. Martinho O, Gouveia A, Viana-Pereira M, Silva P, Pimenta A, Reis RM, Lopes JM

Low frequency of MAP kinase pathway alterations in KIT and PDGFRA wild-type GISTs. Histopathology 55: 53-62, 2009.  [Article] 

 doi: 10.1111/j.1365-2559.2009.03323.x PMID: 19614767.

 

139. Celestino R, Magalhães J, Castro P, Triller M, Vinagre J, Soares P, Sobrinho-Simões M

A follicular variant of papillary thyroid carcinoma in struma ovarii. Case report with unique molecular alterations. Histopathology 55: 482-7, 2009.  [Letter] 

 doi: 10.1111/j.1365-2559.2009.03401.x PMID: 19817905.

 

140. Xavier CP, Lima CF, Preto A, Seruca R, Fernandes-Ferreira M, Pereira-Wilson C

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer letters 281: 162-70, 2009.  [Article] 

 doi: 10.1016/j.canlet.2009.02.041 PMID: 19344998.

 

141. Martinho O, Granja S, Jaraquemada T, Caeiro C, Miranda-Gonçalves V, Honavar M, Costa P, Damasceno M, Rosner MR, Lopes JM, Reis RM

Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. PloS one 7: e30769, 2012.  [Article] 

 doi: 10.1371/journal.pone.0030769 PMID: 22292035.

 

142. Couto JP, Almeida A, Daly L, Sobrinho-Simões M, Bromberg JF, Soares P

AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines. PloS one 7: e46869, 2012.  [Article] 

 doi: 10.1371/journal.pone.0046869 PMID: 23056499.

 

143. Soares NCP, Teodoro AJ, Oliveira FL, Santos CAN, Takiya CM, Junior OS, Bianco M, Palumbo A, Ferreira LB, Gimba EP EP, Borojevic R

Influence of Lycopene on Cell Viability, Cell Cycle and Apoptosis of Human Prostate Cancer and Benign Hyperplastic Cells. PloS one  1, 2012.  [] 

.

 

144. Nogueira AM, Carneiro F, Seruca R, Cirnes L, Veiga I, Machado JC, Sobrinho-Simões M

Microsatellite instability in hyperplastic and adenomatous polyps of the stomach. Cancer 86: 1649-56, 1999.  [Article] 

 PMID: 10547536.

 

145. Portovedo S, Gaido N, de Almeida Nunes B, Nascimento AG, Rocha A, Magalhães M, Nascimento GC, Pires de Carvalho D, Soares P, Takiya C, Faria MDS, Miranda-Alves L

Differential Expression of HMGA1 and HMGA2 in pituitary neuroendocrine tumors. Molecular and cellular endocrinology 490: 80-87, 2019.  [Article] 

 doi: 10.1016/j.mce.2019.04.010 PMID: 30999005.

 

146. Máximo V, Lima J, Soares P, Silva A, Bento I, Sobrinho-Simões M

GRIM-19 in Health and Disease. Advances in anatomic pathology 15: 46-53, 2008.  [Editorial Material] 

 doi: 10.1097/PAP.0b013e31815e5258 PMID: 18156812.

 

147. Ferreira LB, Lima RT, Bastos ACSDF, Silva AM, Tavares C, Pestana A, Rios E, Eloy C, Sobrinho-Simões M, Gimba ERP, Soares P

OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines. International journal of molecular sciences 19: ., 2018.  [Article] 

 doi: 10.3390/ijms19102990 PMID: 30274371.

 

148. Tavares C, Eloy C, Melo M, Gaspar da Rocha A, Pestana A, Batista R, Bueno Ferreira L, Rios E, Sobrinho Simões M, Soares P

mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression. International journal of molecular sciences 19: ., 2018.  [Article] 

 doi: 10.3390/ijms19051448 PMID: 29757257.

 

149. Alvelos MI, Vinagre J, Fonseca E, Barbosa E, Teixeira-Gomes J, Sobrinho-Simões M, Soares P

MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism. European journal of endocrinology 168: 119-28, 2013.  [Article] 

 doi: 10.1530/EJE-12-0327 PMID: 23093699.

 

150. Boaventura P, Pereira D, Celestino R, Mendes A, Nakasawa T, Teixeira-Gomes J, Sobrinho-Simões M, Soares P

Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment. European journal of endocrinology 169: 673-679, 2013.  [Article] 

 doi: 10.1530/EJE-13-0543 PMID: 23966419.

 

151. Lima RT, Martins LM, Guimarães JE, Sambade C, Vasconcelos MH

Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. Cancer gene therapy 11: 309-16, 2004.  [Article] 

 doi: 10.1038/sj.cgt.7700706 PMID: 15031723.

 

152. Silva LS, Goncalves LG, Silva F, Domingues G, Maximo V, Ferreira J, Lam EW, Dias S, Felix A, Serpa J

STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 37: 5385-95, 2016.  [Article] 

 doi: 10.1007/s13277-015-4385-z PMID: 26563366.

 

153. Cárcano FM, Vidal DO, van Helvoort Lengert A, Neto CS, Queiroz L, Marques H, Baltazar F, da Silva Martinelli CM, Soares P, da Silva EC, Lopes LF, Reis RM

Hotspot TERT promoter mutations are rare events in testicular germ cell tumors. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 37: 4901-7, 2016.  [Article] 

 doi: 10.1007/s13277-015-4317-y PMID: 26526580.

 

154. Preto A, Cameselle-Teijeiro J, Moldes-Boullosa J, Soares P, Cameselle-Teijeiro JF, Silva P, Reis-Filho JS, Reyes-Santías RM, Alfonsín-Barreiro N, Forteza J, Sobrinho-Simões M

Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 17: 819-26, 2004.  [Article] 

 doi: 10.1038/modpathol.3800124 PMID: 15044923.

 

155. Pignatelli D, Carvalho BL, Palmeiro A, Barros A, Guerreiro SG, Maçut D

The Complexities in Genotyping of Congenital Adrenal Hyperplasia: 21-Hydroxylase Deficiency. Frontiers in endocrinology 10: 432, 2019.  [Review] 

 doi: 10.3389/fendo.2019.00432 PMID: 31333583.

 

156. Moreira S, Correia M, Soares P, Máximo V

GRIM-19 function in cancer development. Mitochondrion 11: 693-9, 2011.  [Review] 

 doi: 10.1016/j.mito.2011.05.011 PMID: 21664299.

 

157. Correia M, Casal S, Vinagre J, Seruca R, Figueiredo C, Touati E, Machado JC

Helicobacter pylori's cholesterol uptake impacts resistance to docosahexaenoic acid. International journal of medical microbiology : IJMM 304: 314-20, 2014.  [Article] 

 doi: 10.1016/j.ijmm.2013.11.018 PMID: 24447914.

 

158. Carneiro F, Sobrinho-Simoes M

The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer 88: 238-40, 2000.  [Letter] 

 PMID: 10618628.

 

159. Sobrinho-Simões M

Hail to the histologic grading of papillary thyroid carcinoma? Cancer 88: 1766-8, 2000.  [Editorial Material] 

 PMID: 10760750.

 

160. Amorim JP, Santos G, Vinagre J, Soares P

The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype. Genes 7: 1, 2016.  [Review] 

 doi: 10.3390/genes7090066 PMID: 27657132.

 

161. Saieg MA, Cury AN, Oliveira AK, Nascimento AO, Melo M, Soares P, Sobrinho-Simões M

Study of the histological profile of papillary thyroid carcinoma associated to hashimoto thyroiditis Histopathology  192, 2010.  [Meeting Abstract] 

.

 

162. Alvarenga CA, Vinagre J, Paravidino PI, Alvarenga MA, Billish A, Castilho LN, Prando A, Soares P, Lopes JM

Paraganglioma of vesicle seminal and chromophobe renal cell carcinoma: a rare sporadic or hereditary association? Histopathology  243, 2010.  [Meeting Abstract] 

.

 

163. Celestino R, Sigstad E, Løvf M, Thomassen GO, Grøholt KK, Jørgensen LH, Berner A, Castro P, Lothe RA, Bjøro T, Sobrinho-Simões M, Soares P, Skotheim RI

Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes. Genes, chromosomes & cancer 51: 1154-64, 2012.  [Article] 

 doi: 10.1002/gcc.22003 PMID: 22961909.

 

164. Falconi M, Bartsch DK, Eriksson B, Klöppel G, Lopes JM, O'Connor JM, Salazar R, Taal BG, Vullierme MP, O'Toole D,

ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms of the digestive system: well-differentiated pancreatic non-functioning tumors. Neuroendocrinology 95: 120-34, 2012.  [Article] 

 doi: 10.1159/000335587 PMID: 22261872.

 

165. Caplin M, Sundin A, Nillson O, Baum RP, Klose KJ, Kelestimur F, Plöckinger U, Papotti M, Salazar R, Pascher A, Lopes JM

ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: colorectal neuroendocrine neoplasms. Neuroendocrinology 95: 88-97, 2012.  [Article] 

 doi: 10.1159/000335594 PMID: 22261972.

 

166. de-Freitas-Junior JC, Carvalho S, Dias AM, Oliveira P, Cabral J, Seruca R, Oliveira C, Morgado-Díaz JA, Reis CA, Pinho SS

Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin. PloS one 8: e81579, 2013.  [Article] 

 doi: 10.1371/journal.pone.0081579 PMID: 24282611.

 

167. Marques PI, Ferreira Z, Martins M, Figueiredo J, Silva DI, Castro P, Morales-Hojas R, Simões-Correia J, Seixas S

SERPINA2 Is a Novel Gene with a Divergent Function from SERPINA1. PloS one 8: e66889, 2013.  [Article] 

 doi: 10.1371/journal.pone.0066889 PMID: 23826168.

 

168. Berto-Júnior C, de Carvalho DP, Soares P, Miranda-Alves L

Tributyltin and Zebrafish: Swimming in Dangerous Water. Frontiers in endocrinology 9: 152, 2018.  [Review] 

 doi: 10.3389/fendo.2018.00152 PMID: 29692757.

 

169. Pérez-Cabezas B, Cecílio P, Gaspar TB, Gärtner F, Vasconcellos R, Cordeiro-da-Silva A

Understanding Resistance vs. Susceptibility in Visceral Leishmaniasis Using Mouse Models of Leishmania infantum Infection. Frontiers in cellular and infection microbiology 9: 30, 2019.  [Article] 

 doi: 10.3389/fcimb.2019.00030 PMID: 30881923.

 

170. Batista R, Vinagre J, Prazeres H, Sampaio C, Peralta P, Conceição P, Sismeiro A, Leão R, Gomes A, Furriel F, Oliveira C, Torres JN, Eufrásio P, Azinhais P, Almeida F, Gonzalez ER, Bidovanets B, Ecke T, Stinjs P, Pascual ÁS, Abdelmalek R, Villafruela A, Beardo-Villar P, Fidalgo N, Öztürk H, Gonzalez-Enguita C, Monzo J, Lopes T, Álvarez-Maestro M, Servan PP, De La Cruz SMP, Perez MPS, Máximo V, Soares P

Validation of a Novel, Sensitive, and Specific Urine-Based Test for Recurrence Surveillance of Patients With Non-Muscle-Invasive Bladder Cancer in a Comprehensive Multicenter Study. Frontiers in genetics 10: 1237, 2019.  [Article] 

 doi: 10.3389/fgene.2019.01237 PMID: 31921291.

 

171. Santos-Silva F, Fonseca A, Caffrey T, Carvalho F, Mesquita P, Reis C, Almeida R, David L, Hollingsworth MA

Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. Glycobiology 15: 511-7, 2005.  [Article] 

 doi: 10.1093/glycob/cwi027 PMID: 15604091.

 

172. Rodrigues AR, Pignatelli D, Almeida H, Gouveia AM

Melanocortin 5 receptor activates ERK1/2 through a PI3K-regulated signaling mechanism. Molecular and cellular endocrinology 303: 74-81, 2009.  [Article] 

 doi: 10.1016/j.mce.2009.01.014 PMID: 19428994.

 

173. Song R, Duarte TL, Almeida GM, Farmer PB, Cooke MS, Zhang W, Sheng G, Fu J, Jones GD

Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. Toxicology letters 185: 23-31, 2009.  [Article] 

 doi: 10.1016/j.toxlet.2008.11.011 PMID: 19095052.

 

174. Cavadas B, Pereira JB, Correia M, Fernandes V, Eloy C, Sobrinho-Simões M, Soares P, Samuels DC, Máximo V, Pereira L

Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background. Mitochondrion 46: 123-133, 2019.  [Article] 

 doi: 10.1016/j.mito.2018.04.001 PMID: 29631022.

 

175. Pena MJ, Guerreiro SG, Rocha JC, Morais T, Pereira SS, Monteiro MP, Borges N

Acute effect of an amino acid mixture in the rat glycemic profile. Journal of cellular biochemistry 120: 13056-13065, 2019.  [Article] 

 doi: 10.1002/jcb.28576 PMID: 30873675.

 

176. Boaventura P, Pereira D, Mendes A, Batista R, da Silva AF, Guimarães I, Honavar M, Teixeira-Gomes J, Lopes JM, Máximo V, Soares P

Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas. Journal of dermatological science 73: 31-9, 2014.  [Article] 

 doi: 10.1016/j.jdermsci.2013.09.002 PMID: 24091058.

 

177. Trovisco V, Couto JP, Cameselle-Teijeiro J, de Castro IV, Fonseca E, Soares P, Sobrinho-Simões M

Acquisition of BRAF gene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma. Clinical endocrinology 69: 683-5, 2008.  [Letter] 

 doi: 10.1111/j.1365-2265.2008.03243.x PMID: 18363883.

 

178. Vilas-Boas F, Magro F, Balhau R, Lopes JM, Beça F, Eloy C, Lopes S, Macedo G

Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: case report and review of the literature. Journal of Crohn's & colitis 6: 792-5, 2012.  [Review] 

 doi: 10.1016/j.crohns.2012.03.004 PMID: 22464812.

 

179. Pereira-Castro I, Costa AM, Oliveira MJ, Barbosa I, Rocha AS, Azevedo L, da Costa LT

Characterization of human NLZ1/ZNF703 identifies conserved domains essential for proper subcellular localization and transcriptional repression. Journal of cellular biochemistry 114: 120-33, 2013.  [Article] 

 doi: 10.1002/jcb.24309 PMID: 22886885.

 

180. Mesquita P, Raquel A, Nuno L, Reis CA, Silva LF, Serpa J, Van Seuningen I, Barros H, David L

Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal metaplasia. Critical reviews in oncogenesis 12: 3-26, 2006.  [] 

 PMID: 17078204.

 

181. Reis CA, David L, Nielsen PA, Clausen H, Mirgorodskaya K, Roepstorff P, Sobrinho-Simões M

Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody. International journal of cancer 74: 112-21, 1997.  [Article] 

 PMID: 9036879.

 

182. Soares P, Berx G, van Roy F, Sobrinho-Simões M

E-cadherin gene alterations are rare events in thyroid tumors. International journal of cancer 70: 32-8, 1997.  [Article] 

 PMID: 8985087.

 

183. Camilo V, Barros R, Celestino R, Castro P, Vieira J, Teixeira MR, Carneiro F, Pinto-de-Sousa J, David L, Almeida R

Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome. BMC cancer 14: 753, 2014.  [Article] 

 doi: 10.1186/1471-2407-14-753 PMID: 25300947.

 

184. Prazeres HJ, Rodrigues F, Figueiredo P, Naidenov P, Soares P, Bugalho MJ, Lacerda M, Campos B, Martins TC

Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal. Clinical endocrinology 64: 659-66, 2006.  [Article] 

 doi: 10.1111/j.1365-2265.2006.02524.x PMID: 16712668.

 

185. Reis-Filho JS, Preto A, Soares P, Ricardo S, Cameselle-Teijeiro J, Sobrinho-Simões M

p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 16: 43-8, 2003.  [Article] 

 doi: 10.1097/01.MP.0000047306.72278.39 PMID: 12527712.

 

186. Cameselle-Teijeiro J, Pardal F, Eloy C, Ruiz-Ponte C, Celestino R, Castro P, Soares P, Sobrinho-Simões M

Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth. Human pathology 39: 1540-7, 2008.  [Article] 

 doi: 10.1016/j.humpath.2008.01.014 PMID: 18602667.

 

187. Pimenta AP, Preto JR, Gouveia AM, Fonseca E, Pimenta MM

Mediastinal tuberculous lymphadenitis presenting as an esophageal intramural tumor: a very rare but important cause for dysphagia. World journal of gastroenterology 13: 6104-8, 2007.  [Article] 

 PMID: 18023110.

 

188. Løvf M, Thomassen GO, Bakken AC, Celestino R, Fioretos T, Lind GE, Lothe RA, Skotheim RI

Fusion gene microarray reveals cancer type-specificity among fusion genes. Genes, chromosomes & cancer 50: 348-57, 2011.  [Article] 

 doi: 10.1002/gcc.20860 PMID: 21305644.

 

189. Boos LA, Dettmer M, Schmitt A, Rudolph T, Steinert H, Moch H, Sobrinho-Simões M, Komminoth P, Perren A

Diagnostic and prognostic implications of the PAX8-PPAR¿ translocation in thyroid carcinomas-a TMA-based study of 226 cases. Histopathology 63: 234-41, 2013.  [Article] 

 doi: 10.1111/his.12150 PMID: 23738683.

 

190. Nogueira AM, Machado JC, Carneiro F, Reis CA, Gött P, Sobrinho-Simões M

Patterns of expression of trefoil peptides and mucins in gastric polyps with and without malignant transformation. The Journal of pathology 187: 541-8, 1999.  [Article] 

 doi: 10.1002/(SICI)1096-9896(199904)187:5<541::AID-PATH283>3.0.CO;2-9 PMID: 10398119.

 

191. Pereira D, Lima RT, Palmeira A, Seca H, Soares J, Gomes S, Raimundo L, Maciel C, Pinto M, Sousa E, Vasconcelos MH, Saraiva L, Cidade H

Design and synthesis of new inhibitors of p53-MDM2 interaction with a chalcone scaffold Arabian Journal of Chemistry 12: 4150-4161, 2019.  [Article] 

 doi: 10.1016/j.arabjc.2016.04.015.

 

192. Pestana A, Vinagre J, Sobrinho-Simões M, Soares P

TERT biology and function in cancer: beyond immortalisation. Journal of molecular endocrinology 58: R129-R146, 2017.  [Review] 

 doi: 10.1530/JME-16-0195 PMID: 28057768.

 

193. Saavedra A, Lima J, Castro L, Silva R, Macedo S, Rodrigues E, Carvalho D

Malignant paraganglioma and somatotropinoma in a patient with germline SDHB mutation-genetic and clinical features. Endocrine 63: 182-187, 2019.  [Article] 

 doi: 10.1007/s12020-018-1726-x PMID: 30155846.

 

194. Pereira SS, Monteiro MP, Costa MM, Moreira Â, Alves MG, Oliveira PF, Jarak I, Pignatelli D

IGF2 role in adrenocortical carcinoma biology. Endocrine 66: 326-337, 2019.  [Article] 

 doi: 10.1007/s12020-019-02033-5 PMID: 31378849.

 

195. Celestino R, Nome T, Pestana A, Hoff AM, Gonçalves AP, Pereira L, Cavadas B, Eloy C, Bjøro T, Sobrinho-Simões M, Skotheim RI, Soares P

CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension. BMC cancer 18: 68, 2018.  [Article] 

 doi: 10.1186/s12885-017-3948-3 PMID: 29321030.

 

196. Reis CA, David L, Seixas M, Burchell J, Sobrinho-Simões M

Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma. International journal of cancer 79: 402-10, 1998.  [Article] 

 PMID: 9699534.

 

197. Kos-Kudla B, O'Toole D, Falconi M, Gross D, Klöppel G, Sundin A, Ramage J, Oberg K, Wiedenmann B, Komminoth P, Van Custem E, Mallath M, Papotti M, Caplin M, Collaborators, including Lopes JM .

ENETS consensus guidelines for the management of bone and lung metastases from neuroendocrine tumors. Neuroendocrinology 91: 341-50, 2010.  [Article] 

 doi: 10.1159/000287255 PMID: 20484875.

 

198. Pavel M, Grossman A, Arnold R, Perren A, Kaltsas G, Steinmüller T, de Herder W, Nikou G, Plöckinger U, Lopes JM, Sasano H, Buscombe J, Lind P, O'Toole D, Oberg K, Conference Participant Palma de Mallorca Consensus

ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors. Neuroendocrinology 91: 326-32, 2010.  [Article] 

 doi: 10.1159/000287277 PMID: 20453466.

 

199. Kianmanesh R, Ruszniewski P, Rindi G, Kwekkeboom D, Pape UF, Kulke M, Sevilla Garcia I, Scoazec JY, Nilsson O, Fazio N, Lesurtel M, Chen YJ, Eriksson B, Cioppi F, O'Toole D, Collaborators, including Lopes JM .

ENETS consensus guidelines for the management of peritoneal carcinomatosis from neuroendocrine tumors. Neuroendocrinology 91: 333-40, 2010.  [Article] 

 doi: 10.1159/000286700 PMID: 20424420.

 

200. O'Toole D, Rindi G, Plöckinger U, Wiedenmann B, Collaborators, including Lopes JM

ENETS consensus guidelines for the management of patients with rare metastases from digestive neuroendocrine tumors: rationale and working framework. Introduction. Neuroendocrinology 91: 324-5, 2010.  [Editorial Material] 

 doi: 10.1159/000287272 PMID: 20407213.

 

201. Almeida LA, Araujo R

Highlights on molecular identification of closely related species. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 13: 67-75, 2013.  [Review] 

 doi: 10.1016/j.meegid.2012.08.011 PMID: 22982158.

 

202. Esteves C, Maia T, Lopes JM, Pimenta M

Malignant Solitary Fibrous Tumor of the Liver: AIRP Best Cases in Radiologic-Pathologic Correlation. Radiographics : a review publication of the Radiological Society of North America, Inc 37: 2018-2025, 2017.  [Article] 

 doi: 10.1148/rg.2017160200 PMID: 29131777.

 

203. Bauer J, Weng J, Kebebew E, Soares P, Trovisco V, Bastian BC

Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer. Experimental dermatology 18: 548-52, 2009.  [Article] 

 doi: 10.1111/j.1600-0625.2008.00827.x PMID: 19493000.

 

204. Durães C, Moreira CS, Alvelos I, Mendes A, Santos LR, Machado JC, Melo M, Esteves C, Neves C, Sobrinho-Simões M, Soares P

Polymorphisms in the TNFA and IL6 genes represent risk factors for autoimmune thyroid disease. PloS one 9: e105492, 2014.  [Article] 

 doi: 10.1371/journal.pone.0105492 PMID: 25127106.

 

205. Gameiro P, Vieira S, Carrara P, Silva AL, Diamond J, Botelho de Sousa A, Mehta AB, Prentice HG, Guimarães JE, Hoffbrand AV, Foroni L, Parreira A

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients. Haematologica 86: 577-85, 2001.  [Article] 

 PMID: 11418366.

 

206. Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle. European journal of medicinal chemistry 45: 5628-34, 2010.  [Article] 

 doi: 10.1016/j.ejmech.2010.09.014 PMID: 20926160.

 

207. Lima AR, Santos L, Correia M, Soares P, Sobrinho-Simões M, Melo M, Máximo V

Dynamin-Related Protein 1 at the Crossroads of Cancer. Genes 9: ., 2018.  [Review] 

 doi: 10.3390/genes9020115 PMID: 29466320.

 

208. Gaspar TB, Sá A, Lopes JM, Sobrinho-Simões M, Soares P, Vinagre J

Telomere Maintenance Mechanisms in Cancer. Genes 9: ., 2018.  [Review] 

 doi: 10.3390/genes9050241 PMID: 29751586.

 

209. Penna GC, Pestana A, Cameselle JM, Momesso D, de Andrade FA, Vidal APA, Araujo Junior ML, Melo M, Fernandes PV, Corbo R, Vaisman M, Sobrinho-Simões M, Soares P, Vaisman F

TERTp mutation is associated with a shorter progression free survival in patients with aggressive histology subtypes of follicular-cell derived thyroid carcinoma. Endocrine 61: 489-498, 2018.  [Article] 

 doi: 10.1007/s12020-018-1642-0 PMID: 29948935.

 

210. Alves C, Silva F, Gusmão L, Seruca R, Soares P, Reis RM, Amorim A

Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours. European journal of human genetics : EJHG 8: 540-4, 2000.  [Article] 

 doi: 10.1038/sj.ejhg.5200486 PMID: 10909855.

 

211. Crespigio J, Berbel LCL, Dias MA, Berbel RF, Pereira SS, Pignatelli D, Mazzuco TL

Von Hippel-Lindau disease: a single gene, several hereditary tumors. Journal of endocrinological investigation 41: 21-31, 2018.  [Review] 

 doi: 10.1007/s40618-017-0683-1 PMID: 28589383.

 

212. Pereira SS, Pereira R, Santos AP, Costa MM, Morais T, Sampaio P, Machado B, Afonso LP, Henrique R, Monteiro MP

Higher IL-6 peri-tumoural expression is associated with gastro-intestinal neuroendocrine tumour progression. Pathology 51: 593-599, 2019.  [Article] 

 doi: 10.1016/j.pathol.2019.07.001 PMID: 31466863.

 

213. Cameselle-Teijeiro J, Ruiz-Ponte C, Loidi L, Suarez-Peñaranda J, Baltar J, Sobrinho-Simoes M

Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma. American journal of clinical pathology 115: 486-93, 2001.  [Article] 

 doi: 10.1309/T9CC-JNMD-1WGP-YPAF PMID: 11293895.

 

214. Pall M, Azziz R, Beires J, Pignatelli D

The phenotype of hirsute women: a comparison of polycystic ovary syndrome and 21-hydroxylase-deficient nonclassic adrenal hyperplasia. Fertility and sterility 94: 684-9, 2010.  [Article] 

 doi: 10.1016/j.fertnstert.2009.06.025 PMID: 19726039.

 

215. Bizarro A, Sousa D, Lima RT, Musso L, Cincinelli R, Zuco V, De Cesare M, Dallavalle S, Vasconcelos MH

Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors. Molecules (Basel, Switzerland) 23: ., 2018.  [Article] 

 doi: 10.3390/molecules23020407 PMID: 29438315.

 

216. Manco L, Ribeiro ML, Máximo V, Almeida H, Costa A, Freitas O, Barbot J, Abade A, Tamagnini G

A new PKLR gene mutation in the R-type promoter region affects the gene transcription causing pyruvate kinase deficiency. British journal of haematology 110: 993-7, 2000.  [Article] 

 PMID: 11054094.

 

217. Ferreira-da-Silva A, Valacca C, Rios E, Pópulo H, Soares P, Sobrinho-Simões M, Scorrano L, Máximo V, Campello S

Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration. PloS one 10: e0122308, 2015.  [Article] 

 doi: 10.1371/journal.pone.0122308 PMID: 25822260.

 

218. Bartosch C, Monteiro-Reis S, Vieira R, Pereira A, Rodrigues M, Jerónimo C, Lopes JM

Endometrial Endometrioid Carcinoma Metastases Show Decreased ER-Alpha and PR-A Expression Compared to Matched Primary Tumors. PloS one 10: e0134969, 2015.  [Article] 

 doi: 10.1371/journal.pone.0134969 PMID: 26252518.

 

219. Granjo E, Lima M, Lopes JM, Cunha N, Teixeira Mdos A, Santos F, Candeias J, Resende C, Santos AH, Balanzategui A, Orfão A, Matutes E

Intraclonal diversity in a Sezary syndrome with a differential response to 2-deoxycoformycin of the two lymphoma cell populations. British journal of haematology 119: 629-33, 2002.  [Article] 

 PMID: 12437636.

 

220. Lima J, Trovisco V, Soares P, Máximo V, Magalhães J, Salvatore G, Santoro M, Bogdanova T, Tronko M, Abrosimov A, Jeremiah S, Thomas G, Williams D, Sobrinho-Simões M

Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. Cancer letters 230: 149-50, 2005.  [Letter] 

 doi: 10.1016/j.canlet.2004.10.053 PMID: 16253771.

 

221. Tavares C, Coelho MJ, Eloy C, Melo M, da Rocha AG, Pestana A, Batista R, Ferreira LB, Rios E, Selmi-Ruby S, Cavadas B, Pereira L, Sobrinho Simões M, Soares P

NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features. Endocrine connections 7: 78-90, 2018.  [Article] 

 doi: 10.1530/EC-17-0302 PMID: 29298843.

 

222. Falcão-Pires I, Gonçalves N, Moura C, Lamego I, Eloy C, Lopes JM, Begieneman MP, Niessen HW, Areias JC, Leite-Moreira AF

Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function. American journal of hypertension 22: 1190-8, 2009.  [Article] 

 doi: 10.1038/ajh.2009.159 PMID: 19745820.

 

223. Martins-Mendes D, Monteiro-Soares M, Boyko EJ, Ribeiro M, Barata P, Lima J, Soares R

The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. Journal of diabetes and its complications 28: 632-8, 2014.  [Article] 

 doi: 10.1016/j.jdiacomp.2014.04.011 PMID: 24877985.

 

224. Cameselle-Teijeiro J, Abdulkader I, Pérez-Becerra R, Vázquez-Boquete A, Alberte-Lista L, Ruiz-Ponte C, Forteza J, Sobrinho-Simões M

BRAF mutation in solid cell nest hyperplasia associated with papillary thyroid carcinoma. A precursor lesion? Human pathology 40: 1029-35, 2009.  [Article] 

 doi: 10.1016/j.humpath.2008.11.015 PMID: 19269016.

 

225. Pereira SS, Monteiro MP, Costa MM, Ferreira J, Alves MG, Oliveira PF, Jarak I, Pignatelli D

MAPK/ERK pathway inhibition is a promising treatment target for adrenocortical tumors. Journal of cellular biochemistry 120: 894-906, 2019.  [Article] 

 doi: 10.1002/jcb.27451 PMID: 30256438.

 

226. Pereira SS, Máximo V, Coelho R, Batista R, Soares P, Guerreiro SG, Sobrinho-Simões M, Monteiro MP, Pignatelli D

Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas. Journal of cellular biochemistry 118: 2064-2071, 2017.  [Article] 

 doi: 10.1002/jcb.25811 PMID: 27886397.

 

227. Pinto-de-Sousa J, Silva F, David L, Leitão D, Seixas M, Pimenta A, Cardoso-de-Oliveira M

Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma. Histopathology 44: 323-31, 2004.  [Article] 

 doi: 10.1111/j.1365-2559.2004.01852.x PMID: 15049897.

 

228. Woenckhaus C, Cameselle-Teijeiro J, Ruiz-Ponte C, Abdulkader I, Reyes-Santías R, Sobrinho-Simões M

Spindle cell variant of papillary thyroid carcinoma. Histopathology 45: 424-7, 2004.  [Letter] 

 doi: 10.1111/j.1365-2559.2004.01916.x PMID: 15469488.

 

229. Rocha AS, Soares P, Fonseca E, Cameselle-Teijeiro J, Oliveira MC, Sobrinho-Simões M

E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas. Histopathology 42: 580-7, 2003.  [Article] 

 PMID: 12786894.

 

230. Cameselle-Teijeiro J, Manuel Lopes J, Villanueva JP, Gil-Gil P, Sobrinho-Simões M

Lipomatous haemangiopericytoma (adipocytic variant of solitary fibrous tumour) of the thyroid. Histopathology 43: 406-8, 2003.  [Letter] 

 PMID: 14511266.

 

231. Carneiro F, Machado JC, Nabais S, Santos CM, Sobrinho Simões M

Mixed carcinoma of the stomach: a clinicopathological entity. Histopathology 43: 94-5, 2003.  [Letter] 

 PMID: 12823718.

 

232. Cameselle-Teijeiro J, Abdulkader I, Soares P, Alfonsín-Barreiro N, Moldes-Boullosa J, Sobrinho-Simões M

Cystic tumor of the atrioventricular node of the heart appears to be the heart equivalent of the solid cell nests (ultimobranchial rests) of the thyroid. American journal of clinical pathology 123: 369-75, 2005.  [Article] 

 doi: 10.1309/GWT2-PY0T-77PB-BA1A PMID: 15716232.

 

233. Oliveira G, Polónia A, Cameselle-Teijeiro JM, Leitão D, Sapia S, Sobrinho-Simões M, Eloy C

EWSR1 rearrangement is a frequent event in papillary thyroid carcinoma and in carcinoma of the thyroid with Ewing family tumor elements (CEFTE). Virchows Archiv : an international journal of pathology 470: 517-525, 2017.  [Article] 

 doi: 10.1007/s00428-017-2095-1 PMID: 28236059.

 

234. Maia T, Amendoeira I

Breast sebaceous carcinoma-a rare entity. Clinico-pathological description of two cases and brief review. Virchows Archiv : an international journal of pathology 472: 877-880, 2018.  [Review] 

 doi: 10.1007/s00428-018-2327-z PMID: 29556777.

 

235. Canberk S, Pereira L, Batista R, Soares P, Maximo V, Simoes MS

DICER1 alterations are more frequent in oncocytic, follicular and rare aggressive variants than in classical papillary thyroid carcinoma Virchows Archiv 473: S67-S67, 2018.  [Meeting Abstract] 

.

 

236. Berto-Júnior C, Santos-Silva AP, Ferreira ACF, Graceli JB, de Carvalho DP, Soares P, Romeiro NC, Miranda-Alves L

Unraveling molecular targets of bisphenol A and S in the thyroid gland. Environmental science and pollution research international 25: 26916-26926, 2018.  [Article] 

 doi: 10.1007/s11356-018-2419-y PMID: 30006815.

 

237. Steinmüller T, Kianmanesh R, Falconi M, Scarpa A, Taal B, Kwekkeboom DJ, Lopes JM, Perren A, Nikou G, Yao J, Delle Fave GF, O'Toole D,

Consensus guidelines for the management of patients with liver metastases from digestive (neuro)endocrine tumors: foregut, midgut, hindgut, and unknown primary. Neuroendocrinology 87: 47-62, 2008.  [Article; Proceedings Paper] 

 doi: 10.1159/000111037 PMID: 18097131.

 

238. Eriksson B, Klöppel G, Krenning E, Ahlman H, Plöckinger U, Wiedenmann B, Arnold R, Auernhammer C, Körner M, Rindi G, Wildi S, Conference participants Frascati Consensus

Consensus guidelines for the management of patients with digestive neuroendocrine tumors--well-differentiated jejunal-ileal tumor/carcinoma. Neuroendocrinology 87: 8-19, 2008.  [Article; Proceedings Paper] 

 doi: 10.1159/000111034 PMID: 18097129.

 

239. Plöckinger U, Couvelard A, Falconi M, Sundin A, Salazar R, Christ E, de Herder WW, Gross D, Knapp WH, Knigge UP, Kulke MH, Pape UF, Frascati Consensus Conference participants, including Lopes JM

Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated tumour/carcinoma of the appendix and goblet cell carcinoma. Neuroendocrinology 87: 20-30, 2008.  [Article; Proceedings Paper] 

 doi: 10.1159/000109876 PMID: 17934252.

 

240. Ramage JK, Goretzki PE, Manfredi R, Komminoth P, Ferone D, Hyrdel R, Kaltsas G, Kelestimur F, Kvols L, Scoazec JY, Garcia MI, Caplin ME, Frascati Consensus Conference participants, including Lopes JM

Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated colon and rectum tumour/carcinoma. Neuroendocrinology 87: 31-9, 2008.  [Article; Proceedings Paper] 

 doi: 10.1159/000111036 PMID: 18097130.

 

241. Ahlman H, Nilsson O, McNicol AM, Ruszniewski P, Niederle B, Ricke J, Jensen R, Kos-Kudla B, Oberg K, O'Connor JM, Pavel ME, Vullierme MP, Conference participants Frascati Consensus

Poorly-differentiated endocrine carcinomas of midgut and hindgut origin. Neuroendocrinology 87: 40-6, 2008.  [Article; Proceedings Paper] 

 doi: 10.1159/000109976 PMID: 17940332.

 

242. Machado JC, Reis CA, Carneiro F, Sobrinho-Simões M

Primary signet-ring cell carcinomas of the lung. Human pathology 31: 272, 2000.  [Letter] 

 PMID: 10685649.

 

243. Pópulo H, Vinagre J, Lopes JM, Soares P

Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas. The British journal of ophthalmology 95: 715-9, 2011.  [Article] 

 doi: 10.1136/bjo.2009.174417 PMID: 20805136.

 

244. Soares P, Sobrinho-Simões M

Correspondence re: G. Tallini et al., RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotype. Clin. Cancer Res., 4:287-294, 1998. Clinical cancer research : an official journal of the American Association for Cancer Research 5: 3724-5, 1999.  [Letter] 

 PMID: 10589793.

 

245. Cameselle-Teijeiro J, Ferreira R, Caramés N, Abdulkader I, Máximo V, Soares P, Sobrinho-Simões M

Absence of the BRAF and the GRIM-19 Mutations in Oncocytic (Hurthle Cell) Solid Cell Nests of the Thyroid. American journal of clinical pathology 137: 612-8, 2012.  [Article] 

 doi: 10.1309/AJCPB0RXYPACLL5K PMID: 22431538.

 

246. Lopes JM, Nesland JM, Reis-Filho JS, Holm R

Differential Ki67 and bcl-2 immunoexpression in solid-glandular and spindle cell components of biphasic synovial sarcoma: a double immunostaining assessment with cytokeratin and vimentin. Histopathology 40: 464-71, 2002.  [Article] 

 PMID: 12010367.

 

247. Nabais S, Machado JC, Lopes C, Seruca R, Carneiro F, Sobrinho-Simões M

Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome. Histopathology 41: 368-9, 2002.  [Letter] 

 PMID: 12383223.

 

248. Martins DF, Rios E

Clear cell chondrosarcoma of the Rib: a rare tumour in an uncommon location Virchows Archiv 475: S408-S409, 2019.  [Meeting Abstract] 

.

 

249. Pinto D, Martins C, Montezuma DF, Canberk S, Schmitt F

Ultrasound data may be used to stratify the risk of malignancy of thyroid nodules classified as follicular neoplasm on fine needle aspiration cytology: a retrospective study of 109 cases Virchows Archiv 475: S13-S13, 2019.  [Meeting Abstract] 

.

 

250. Costa C, Lopes JM, Rios E, Gullo I, Pacheco J

A non-scalp neurocristic cutaneous hamartoma with malignant transformation - a case report and review of literature Virchows Archiv 475: S270-S271, 2019.  [Meeting Abstract] 

.

 

251. de Vries MM, Celestino R, Castro P, Eloy C, Máximo V, van der Wal JE, Plukker JT, Links TP, Hofstra RM, Sobrinho-Simões M, Soares P

RET/PTC rearrangement is prevalent in follicular Hürthle cell carcinomas. Histopathology 61: 833-843, 2012.  [Article] 

 doi: 10.1111/j.1365-2559.2012.04276.x PMID: 22803838.

 

252. Trovisco V, Soares P, Sobrinho-Simões M

B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas. Human pathology 37: 781-6, 2006.  [Article] 

 doi: 10.1016/j.humpath.2006.03.013 PMID: 16784975.

 

253. Rocha AS, Risberg B, Magalhães J, Trovisco V, de Castro IV, Lazarovici P, Soares P, Davidson B, Sobrinho-Simões M

The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma. Human pathology 37: 562-8, 2006.  [Article] 

 doi: 10.1016/j.humpath.2005.12.016 PMID: 16647954.

 

254. Sousa I, Rodrigues F, Prazeres H, Lima RT, Soares P

Liposomal therapies in oncology: does one size fit all? Cancer chemotherapy and pharmacology 82: 741-755, 2018.  [Review] 

 doi: 10.1007/s00280-018-3668-7 PMID: 30116847.

 

255. Boaventura P, Durães C, Mendes A, Costa NR, Chora I, Ferreira S, Araújo E, Lopes P, Rosa G, Marques P, Bettencourt P, Oliveira I, Costa F, Ramos I, Teles MJ, Guimarães JT, Sobrinho-Simões M, Soares P

IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort. PloS one 11: e0163474, 2016.  [Article] 

 doi: 10.1371/journal.pone.0163474 PMID: 27662210.

 

256. Ribeiro R, Monteiro C, Silvestre R, Castela A, Coutinho H, Fraga A, Príncipe P, Lobato C, Costa C, Cordeiro-da-Silva A, Lopes JM, Lopes C, Medeiros R

Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma. Experimental biology and medicine (Maywood, N.J.) 237: 1155-62, 2012.  [Article] 

 doi: 10.1258/ebm.2012.012131 PMID: 23038706.

 

257. Pópulo H, Batista R, Sampaio C, Pardal J, Lopes JM, Soares P

SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma. PloS one 12: e0180392, 2017.  [Article] 

 doi: 10.1371/journal.pone.0180392 PMID: 28662141.

 

258. Carrilho C, Gouveia P, Yokohama H, Lopes JM, Lunet N, Ferro J, Ismail M, Walboomers J, Sobrinho-Simões M, David L

Human papillomaviruses in intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva: a study from Mozambique. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 22: 566-8, 2013.  [Article] 

 doi: 10.1097/CEJ.0b013e328363005d PMID: 23752127.

 

259. Mesquita P, Freire AF, Lopes N, Gomes R, Azevedo D, Barros R, Pereira B, Cavadas B, Pópulo H, Boaventura P, David L, Pereira L, Almeida R

Expression and Clinical Relevance of SOX9 in Gastric Cancer. Disease markers 2019: 8267021, 2019.  [Article] 

 doi: 10.1155/2019/8267021 PMID: 31275454.

 

260. Canberk S, Montezuma D, Tastekin E, Grangeia D, Demirhas MP, Akbas M, Tokat F, Ince U, Soares P, Schmitt F

"The other side of the coin": understanding noninvasive follicular tumor with papillary-like nuclear features in unifocal and multifocal settings. Human pathology 86: 136-142, 2019.  [Article] 

 doi: 10.1016/j.humpath.2018.10.040 PMID: 30529753.

 

261. Preto A, Gonçalves J, Rebocho AP, Figueiredo J, Meireles AM, Rocha AS, Vasconcelos HM, Seca H, Seruca R, Soares P, Sobrinho-Simões M

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations. BMC cancer 9: 387, 2009.  [Article] 

 doi: 10.1186/1471-2407-9-387 PMID: 19878585.

 

262. Máximo V, Soares P, Seruca R, Sobrinho-Simões M

Comments on: mutations in mitochondrial control region DNA in gastric tumours of Japanese patients, Tamura, et al. Eur J Cancer 1999, 35, 316-319. European journal of cancer (Oxford, England : 1990) 35: 1407-8, 1999.  [Letter] 

 PMID: 10658535.

 

263. Meireles AM, Preto A, Rocha AS, Rebocho AP, Máximo V, Pereira-Castro I, Moreira S, Feijão T, Botelho T, Marques R, Trovisco V, Cirnes L, Alves C, Velho S, Soares P, Sobrinho-Simões M

Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid : official journal of the American Thyroid Association 17: 707-15, 2007.  [Article] 

 doi: 10.1089/thy.2007.0097 PMID: 17725429.

 

264. Jensen RT, Niederle B, Mitry E, Ramage JK, Steinmuller T, Lewington V, Scarpa A, Sundin A, Perren A, Gross D, O'Connor JM, Pauwels S, Kloppel G, Consensus Conference Frascati,

Gastrinoma (duodenal and pancreatic). Neuroendocrinology 84: 173-82, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098009 PMID: 17312377.

 

265. Falconi M, Plockinger U, Kwekkeboom DJ, Manfredi R, Korner M, Kvols L, Pape UF, Ricke J, Goretzki PE, Wildi S, Steinmuller T, Oberg K, Scoazec JY, Consensus Conference Frascati,

Well-differentiated pancreatic nonfunctioning tumors/carcinoma. Neuroendocrinology 84: 196-211, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098012 PMID: 17312380.

 

266. de Herder WW, Niederle B, Scoazec JY, Pauwels S, Kloppel G, Falconi M, Kwekkeboom DJ, Oberg K, Eriksson B, Wiedenmann B, Rindi G, O'Toole D, Ferone D, Consensus Conference Frascati,

Well-differentiated pancreatic tumor/carcinoma: insulinoma. Neuroendocrinology 84: 183-8, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098010 PMID: 17312378.

 

267. Ruszniewski P, Delle Fave G, Cadiot G, Komminoth P, Chung D, Kos-Kudla B, Kianmanesh R, Hochhauser D, Arnold R, Ahlman H, Pauwels S, Kwekkeboom DJ, Rindi G, Consensus Conference Frascati,

Well-differentiated gastric tumors/carcinomas. Neuroendocrinology 84: 158-64, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098007 PMID: 17312375.

 

268. Nilsson O, Van Cutsem E, Delle Fave G, Yao JC, Pavel ME, McNicol AM, Sevilla Garcia MI, Knapp WH, Kelestimur F, Sauvanet A, Pauwels S, Kwekkeboom DJ, Caplin M, Consensus Conference Frascati,

Poorly differentiated carcinomas of the foregut (gastric, duodenal and pancreatic). Neuroendocrinology 84: 212-5, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098013 PMID: 17312381.

 

269. O'Toole D, Salazar R, Falconi M, Kaltsas G, Couvelard A, de Herder WW, Hyrdel R, Nikou G, Krenning E, Vullierme MP, Caplin M, Jensen R, Eriksson B, Consensus Conference Frascati,

Rare functioning pancreatic endocrine tumors. Neuroendocrinology 84: 189-95, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098011 PMID: 17312379.

 

270. Jensen RT, Rindi G, Arnold R, Lopes JM, Brandi ML, Bechstein WO, Christ E, Taal BG, Knigge U, Ahlman H, Kwekkeboom DJ, O'Toole D, ,

Well-differentiated duodenal tumor/carcinoma (excluding gastrinomas). Neuroendocrinology 84: 165-72, 2006.  [Article; Proceedings Paper] 

 doi: 10.1159/000098008 PMID: 17312376.

 

271. Eloy C, Santos J, Cameselle-Teijeiro J, Soares P, Sobrinho-Simões M

TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma. Virchows Archiv : an international journal of pathology 460: 587-600, 2012.  [Article] 

 doi: 10.1007/s00428-012-1234-y PMID: 22527019.

 

272. Vinagre J, Celestino R, Gouveia A, Lima J, Faustino A, Soares P

A novel germline SDHB mutation in a GIST patient without associated paraganglioma or pheochromocytoma Virchows Archiv 459: S326-S326, 2012.  [Meeting Abstract] 

.

 

273. Vinagre J, Pópulo H, Azevedo F, Soares P, Lopes JM

 Expression of pS6 Ser235/236 effector of mTOR pathway may be a prognostic parameter in patients with cutaneous melanomas Virchows Archiv  1, 2012.  [Meeting Abstract] 

.

 

274. Vinagre J, Falcão M, Eloy C, Soares P, Lopes JM

A clear cell renal carcinoma causing resistance to VEGF inhibitors in an age-related macular degeneration (AMD)? Virchows Archiv  S49, 2012.  [Meeting Abstract] 

.

 

275. Vinagre J, Pinto V, Celestino R, Reis M, Pópulo H, Boaventura P, Melo M, Catarino T, Lima J, Lopes JM, Máximo V, Sobrinho-Simões M, Soares P

Telomerase promoter mutations in cancer: an emerging molecular biomarker? Virchows Archiv : an international journal of pathology 465: 119-33, 2014.  [Review] 

 doi: 10.1007/s00428-014-1608-4 PMID: 25048572.

 

276. Soares P, Celestino R, Melo M, Fonseca E, Sobrinho-Simões M

Prognostic biomarkers in thyroid cancer. Virchows Archiv : an international journal of pathology 464: 333-46, 2014.  [Review] 

 doi: 10.1007/s00428-013-1521-2 PMID: 24487783.

 

277. Gündisch S, Slotta-Huspenina J, Verderio P, Ciniselli CM, Pizzamiglio S, Schott C, Drecoll E, Viertler C, Zatloukal K, Kap M, Riegman P, Esposito I, Specht K, Babaryka G, Asslaber M, Bodó K, den Bakker M, den Hollander J, Fend F, Neumann J, Reu S, Perren A, Langer R, Lugli A, Becker I, Richter T, Kayser G, May AM, Carneiro F, Lopes JM, Sobin L, Höfler H, Becker KF

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Archiv : an international journal of pathology 465: 509-19, 2014.  [Article] 

 doi: 10.1007/s00428-014-1624-4 PMID: 25085759.

 

278. Boaventura P, Pereira D, Mendes A, Teixeira-Gomes J, Sobrinho-Simões M, Soares P

Thyroid and parathyroid tumours in patients submitted to X-ray scalp epilation during the tinea capitis eradication campaign in the North of Portugal (1950-1963). Virchows Archiv : an international journal of pathology 465: 445-52, 2014.  [Article] 

 doi: 10.1007/s00428-014-1644-0 PMID: 25146169.

 

279. Cameselle-Teijeiro J, Ladra MJ, Abdulkader I, Eloy C, Soares P, Barreiro F, Sobrinho-Simões M, Beiras-Iglesias A

Increased lymphangiogenesis in Riedel thyroiditis (Immunoglobulin G4-related thyroid disease). Virchows Archiv : an international journal of pathology 465: 359-64, 2014.  [Article] 

 doi: 10.1007/s00428-014-1626-2 PMID: 25011997.

 

280. Gouveia AM, Pimenta AP, Capelinha AF, de la Cruz D, Silva P, Lopes JM

Surgical margin status and prognosis of gastrointestinal stromal tumor. World journal of surgery 32: 2375-82, 2008.  [Article] 

 doi: 10.1007/s00268-008-9704-8 PMID: 18685890.

 

281. Santos AL, Coelho R, Silva M, Rios E, Macedo G

Infectious proctitis: a necessary differential diagnosis in ulcerative colitis. International journal of colorectal disease 34: 359-362, 2019.  [Article] 

 doi: 10.1007/s00384-018-3185-5 PMID: 30402768.

 

282. Ferreira JG, Cruz CD, Neves D, Pignatelli D

Increased extracellular signal regulated kinases phosphorylation in the adrenal gland in response to chronic ACTH treatment. The Journal of endocrinology 192: 647-58, 2007.  [Article] 

 doi: 10.1677/joe.1.06961 PMID: 17332532.

 

283. Rocha AS, Marques R, Bento I, Soares R, Magalhães J, de Castro IV, Soares P

Thyroid hormone receptor beta mutations in the 'hot-spot region' are rare events in thyroid carcinomas. The Journal of endocrinology 192: 83-6, 2007.  [Article] 

 doi: 10.1677/JOE-06-0009 PMID: 17210745.

 

284. Cruz J, Reis-Filho JS, Lopes JM

Malignant peripheral nerve sheath tumour-like primary cutaneous malignant melanoma. Journal of clinical pathology 57: 218-20, 2004.  [Article] 

 PMID: 14747458.

 

285. Vazquez Vde L, Vicente AL, Carloni A, Berardinelli G, Soares P, Scapulatempo C, Martinho O, Reis RM

Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas. Melanoma research 26: 93-9, 2016.  [Article] 

 doi: 10.1097/CMR.0000000000000222 PMID: 26709572.

 

286. Mesquita P, Peixoto AJ, Seruca R, Hanski C, Almeida R, Silva F, Reis C, David L

Role of site-specific promoter hypomethylation in aberrant MUC2 mucin expression in mucinous gastric carcinomas. Cancer letters 189: 129-36, 2003.  [Article] 

 PMID: 12490305.

 

287. Reis CA, David L, Carvalho F, Mandel U, de Bolós C, Mirgorodskaya E, Clausen H, Sobrinho-Simões M

Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 48: 377-88, 2000.  [Article] 

 PMID: 10681391.

 

288. Vaz JA, Heleno SA, Martins A, Almeida GM, Vasconcelos MH, Ferreira IC

Wild mushrooms Clitocybe alexandri and Lepista inversa: in vitro antioxidant activity and growth inhibition of human tumour cell lines. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 48: 2881-4, 2010.  [Article] 

 doi: 10.1016/j.fct.2010.07.021 PMID: 20647028.

 

289. Fernandes T, Silva R, Devesa V, Lopes JM, Carneiro F, Viamonte B

AIRP best cases in radiologic-pathologic correlation: gastroblastoma: a rare biphasic gastric tumor. Radiographics : a review publication of the Radiological Society of North America, Inc 34: 1929-33, 2014.  [Article] 

 doi: 10.1148/rg.347130103 PMID: 25384293.

 

290. Rodrigues AG, Mârdh PA, Pina-Vaz C, Martinez-de-Oliveira J, da Fonseca AF

Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines? American journal of obstetrics and gynecology 181: 367-70, 1999.  [Article] 

 PMID: 10454684.

 

291. Cameselle-Teijeiro J, Sobrinho-Simões M

Cytomorphologic features of mucoepidermoid carcinoma of the thyroid. American journal of clinical pathology 111: 134-6, 1999.  [Letter] 

 PMID: 9894464.

 

292. Cameselle-Teijeiro J, Ferreira R, Caramés N, Abdulkader I, Máximo V, Soares P, Sobrinho-Simões M

Absence of both the BRAF and the GRIM-19 mutations in oncocytic (Hürthle cell) solid cell nests of the thyroid American journal of clinical pathology  1, 2011.  [] 

.

 

293. Pópulo H, Nunes B, Sampaio C, Batista R, Pinto MT, Gaspar TB, Miranda-Alves L, Cai RZ, Zhang XY, Schally AV, Sobrinho-Simões M, Soares P

Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer. Hormones & cancer 8: 314-324, 2017.  [Article] 

 doi: 10.1007/s12672-017-0307-4 PMID: 28924876.

 

294. Prudêncio C, Sansonetty F, Sousa MJ, Côrte-Real M, Leão C

Rapid detection of efflux pumps and their relation with drug resistance in yeast cells. Cytometry 39: 26-35, 2000.  [Article] 

 PMID: 10655560.

 

295. Mendes A, Oliveira A, Eloy C, Abreu P

Neuropatia sensitivo-motora axonal por Mycobacterium leprae: um mal da antiguidade no século XXI Sinapse  112, 2009.  [] 

.

 

296. Schmitt FC, Ribeiro CA, Alvarenga S, Lopes JM

Primary acinic cell-like carcinoma of the breast--a variant with good prognosis? Histopathology 36: 286-9, 2000.  [Letter] 

 PMID: 10809602.

 

297. Trovisco V, Soares P, Soares R, Magalhães J, Sá-Couto P, Sobrinho-Simões M

A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma. Human pathology 36: 694-7, 2005.  [Article] 

 doi: 10.1016/j.humpath.2005.04.011 PMID: 16021577.

 

298. Cameselle-Teijeiro J, Preto A, Soares P, Sobrinho-Simões M

A stem cell role for thyroid solid cell nests. Human pathology 36: 590-1, 2005.  [Letter] 

 doi: 10.1016/j.humpath.2005.02.010 PMID: 15948129.

 

299. Quinta-Costa M, Leite M, Simas-Leite P, Correia C, Candeias J, Guimarães JE

Differences in phenotype, growth factor requirements, pattern of expression of adhesion molecules and rate of apoptosis displayed by three new myeloid sister leukemic cell lines. Haematologica 85: 1325-7, 2000.  [Letter] 

 PMID: 11114142.

 

300. Boaventura P, Durães C, Mendes A, Costa NR, Chora I, Ferreira S, Araújo E, Lopes P, Rosa G, Marques P, Tavares S, Chaves V, Bettencourt P, Oliveira I, Costa F, Ramos I, Teles MJ, Guimarães JT, Sobrinho-Simões M, Soares P

Is Low-Dose Radiation Exposure a Risk Factor for Atherosclerotic Disease? Radiation research 189: 418-424, 2018.  [Article] 

 doi: 10.1667/RR14942.1 PMID: 29461943.