1. Oliveira R, Amaro F, Azevedo M, Vale N, Goncalves H, Antunes C, Rego R

New voltammetric and spectroscopic studies to quinacrine-DNA-Cdots interaction Electrochimica Acta 306: 122-131, 2019.  [Article] 

 doi: 10.1016/j.electacta.2019.03.068.

 

2. Pinto da Silva L, Núnez-Montenegro A, Magalhães CM, Ferreira PJO, Duarte D, González-Berdullas P, Rodríguez-Borges JE, Vale N, Esteves da Silva JCG

Single-molecule chemiluminescent photosensitizer for a self-activating and tumor-selective photodynamic therapy of cancer. European journal of medicinal chemistry 183: 111683, 2019.  [Article] 

 doi: 10.1016/j.ejmech.2019.111683 PMID: 31514060.

 

3. Silva S, Almeida AJ, Vale N

Combination of Cell-Penetrating Peptides with Nanoparticles for Therapeutic Application: A Review. Biomolecules 9: ., 2019.  [Review] 

 doi: 10.3390/biom9010022 PMID: 30634689.

 

4. Durão J, Vale N, Gomes S, Gomes P, Barrias CC, Gales L

Nitric Oxide Release from Antimicrobial Peptide Hydrogels for Wound Healing. Biomolecules 9: ., 2018.  [Article] 

 doi: 10.3390/biom9010004 PMID: 30583486.

 

5. Gouveia MJ, Brindley PJ, Rinaldi G, Gärtner F, Correia da Costa JM, Vale N

Combination Anthelmintic/Antioxidant Activity Against Schistosoma Mansoni. Biomolecules 9: ., 2019.  [Article] 

 doi: 10.3390/biom9020054 PMID: 30764562.

 

6. Duarte D, Amaro F, Silva I, Silva D, Fresco P, Oliveira JC, Reguengo H, Gonçalves J, Vale N

Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite. Biomolecules 9: ., 2019.  [Article] 

 doi: 10.3390/biom9090409 PMID: 31450593.

 

7. Ferreira A, Lapa R, Vale N

Combination of Gemcitabine with Cell-Penetrating Peptides: A Pharmacokinetic Approach Using In Silico Tools. Biomolecules 9: ., 2019.  [Article] 

 doi: 10.3390/biom9110693 PMID: 31690028.

 

8. Pinto da Silva L, Magalhães CM, Núñez-Montenegro A, Ferreira PJO, Duarte D, Rodríguez-Borges JE, Vale N, Esteves da Silva JCG

Study of the Combination of Self-Activating Photodynamic Therapy and Chemotherapy for Cancer Treatment. Biomolecules 9: ., 2019.  [Article] 

 doi: 10.3390/biom9080384 PMID: 31434290.

 

9. Duarte D, Fraga AG, Pedrosa J, Martel F, Vale N

Increasing the potential of cell-penetrating peptides for cancer therapy using a new pentagonal scaffold. European journal of pharmacology 860: 172554, 2019.  [Article] 

 doi: 10.1016/j.ejphar.2019.172554 PMID: 31326378.

 

10. Vale N, Ferreira A, Matos J, Fresco P, Gouveia MJ

Amino Acids in the Development of Prodrugs. Molecules (Basel, Switzerland) 23: ., 2018.  [Review] 

 doi: 10.3390/molecules23092318 PMID: 30208629.

 

11. Gouveia MJ, Nogueira V, Araújo B, Gärtner F, Vale N

Inhibition of the Formation In Vitro of Putatively Carcinogenic Metabolites Derived from S. haematobium and O. viverrini by Combination of Drugs with Antioxidants. Molecules (Basel, Switzerland) 24: ., 2019.  [Article] 

 doi: 10.3390/molecules24213842 PMID: 31731402.

 

12. Aguiar L, Biosca A, Lantero E, Gut J, Vale N, Rosenthal PJ, Nogueira F, Andreu D, Fernàndez-Busquets X, Gomes P

Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates. Molecules (Basel, Switzerland) 24: ., 2019.  [Article] 

 doi: 10.3390/molecules24244559 PMID: 31842498.

 

13. Gouveia MJ, Brindley PJ, Azevedo C, Gärtner F, da Costa JMC, Vale N

The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni. Parasites & vectors 12: 309, 2019.  [Article] 

 doi: 10.1186/s13071-019-3566-9 PMID: 31221193.

 

14. Mendes B, Almeida JR, Vale N, Gomes P, Gadelha FR, Da Silva SL, Miguel DC

Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 226: 108612, 2019.  [Article] 

 doi: 10.1016/j.cbpc.2019.108612 PMID: 31454702.

 

15. Gouveia MJ, Brindley PJ, Rinaldi G, Gärtner F, da Costa JMC, Vale N

Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts. Infectious agents and cancer 14: 41, 2019.  [Article] 

 doi: 10.1186/s13027-019-0257-2 PMID: 31798678.

 

16. Silva S, Santos-Silva A, da Costa JMC, Vale N

Potent cationic antimicrobial peptides against Mycobacterium tuberculosis in vitro. Journal of global antimicrobial resistance 19: 132-135, 2019.  [Article] 

 doi: 10.1016/j.jgar.2019.04.018 PMID: 31154008.

 

17. Aguiar L, Machado M, Sanches-Vaz M, Prudêncio M, Vale N, Gomes P

Coupling the cell-penetrating peptides transportan and transportan 10 to primaquine enhances its activity against liver-stage malaria parasites. MedChemComm 10: 221-226, 2019.  [Article] 

 doi: 10.1039/c8md00447a PMID: 30881610.

 

18. Yang V, Pedrosa SS, Fernandes R, Mauricio AC, Koksch B, Gartner F, Amorim I, Vale N

Synthesis of PEGylated methotrexate conjugated with a novel CPP6, in sillico structural insights and activity in MCF-7 cells Journal of Molecular Structure 1192: 201-207, 2019.  [Article] 

 doi: 10.1016/j.molstruc.2019.04.118.

 

19. Silva S, Vale N

Cationic Antimicrobial Peptides for Tuberculosis: A Mini-Review. Current protein & peptide science 20: 885-892, 2019.  [Review] 

 doi: 10.2174/1389203720666190626160057 PMID: 31241433.