M. Helena Vasconcelos
Name: M. Helena Vasconcelos
E-mail: hvasconcelos@ipatimup.pt
Extension: 
225570700
Academic Degree: Doctor of philosophy


M. Helena Vasconcelos
M. Helena Vasconcelos
Member of


Short CV

Highlights

Supervisor of
Bárbara Polónia, Visiting Researcher
Bruna Silva, Visiting Researcher
Catarina Rodrigues, Visiting Researcher
Catarina Antunes, Master Student (thesis)
Cristina Xavier, Post Doc
Helena Branco, Young Researcher (Msc)
Hugo Caires, Junior Researcher
Joana Carreira, Master Student (thesis)
Manuel Areias Sobrinho Simões, Research Consultant
Maria Almeida, Master Student (thesis)
Rita Rebelo, Young Researcher (Msc)
Sara Silva, Fellow

PI (running)

PI (closed)
First Author
 
C
IF
1. Vasconcelos MH, Caires HR, Abols A, Xavier CPR, Line A
Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 47: 100647, 2019. [Review] 
 
Special Issue: New Approaches to Counteract Drug Resistance in Cancer. Molecules (Basel, Switzerland) 22: 1, 2016. [Editorial Material] 
 
3. Vasconcelos MH, Maia LF, Sousa C, Beleza SS, Guimarães JE
Evidence for a specific intracellular localization of an antisense oligonucleotide in k562 cells. Journal of pharmacological sciences 99: 105-8, 2005. [Article] 
 PMID: 16141637.
 
4. Vasconcelos MH, Beleza SS, Quirk C, Maia LF, Sambade C, Guimarães JE
 PMID: 10773404.
 
Senior Author
 
C
IF
1. Assaraf YG, Brozovic A, Gonçalves AC, Jurkovicova D, Line A, Machuqueiro M, Saponara S, Sarmento-Ribeiro AB, Xavier CPR, Vasconcelos MH
The multi-factorial nature of clinical multidrug resistance in cancer. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 46: 100645, 2019. [Review] 
 
2. Teixeira A, DaCunha DC, Barros L, Caires HR, Xavier CPR, Ferreira ICFR, Vasconcelos MH
 doi: 10.1039/c8fo02466a PMID: 31165800.
 
3. Pereira JM, Peixoto V, Teixeira A, Sousa D, Barros L, Ferreira ICFR, Vasconcelos MH
Achillea millefolium L. hydroethanolic extract inhibits growth of human tumor cell lines by interfering with cell cycle and inducing apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 118: 635-644, 2018. [Article] 
 
4. Magalhães DB, Castro I, Lopes-Rodrigues V, Pereira JM, Barros L, Ferreira ICFR, Xavier CPR, Vasconcelos MH
 doi: 10.1039/c8fo00446c PMID: 29790547.
 
5. Bizarro A, Sousa D, Lima RT, Musso L, Cincinelli R, Zuco V, De Cesare M, Dallavalle S, Vasconcelos MH
 
6. Castro I, Lopes-Rodrigues V, Xavier CPR, Vasconcelos MH
gamma-H2AX, CYP3A and CYP2J2 overexpression in a drug-resistant acute myeloid leukemia cell line Free radical biology & medicine 120: S84-S84, 2018. [Meeting Abstract] 
 
7. Magalhães DB, Castro I, Lopes-Rodrigues V, Pereira JM, Barros L, Ferreira ICFR, Xavier CPR, Vasconcelos MH
 
8. Pereira JM, Peixoto V, Teixeira A, Sousa D, Barros L, Ferreira ICFR, Vasconcelos MH
Achillea millefolium L. hydroethanolic extract has phenolic compounds and inhibits the growth of human tumor cell lines Free radical biology & medicine 120: S145-S145, 2018. [Meeting Abstract] 
 
9. Teixeira A, DaCunha DC, Caires HR, Xavier CPR, Barros L, Ferreira ICFR, Vasconcelos MH
Eucalyptus globulus Labill. decoction extract inhibits the growth of human tumor cell lines Free radical biology & medicine 120: S144-S144, 2018. [Meeting Abstract] 
 
10. Lopes-Rodrigues V, Di Luca A, Mleczko J, Meleady P, Henry M, Pesic M, Cabrera D, van Liempd S, Lima RT, O'Connor R, Falcon-Perez JM, Vasconcelos MH
 doi: 10.1038/srep44541 PMID: 28303926.
 
11. Lopes-Rodrigues V, Oliveira A, Correia-da-Silva M, Pinto M, Lima RT, Sousa E, Vasconcelos MH
 
12. Lopes-Rodrigues V, Sousa E, Vasconcelos MH
Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives. Pharmaceuticals (Basel, Switzerland) 9: 1, 2016. [Review] 
 doi: 10.3390/ph9040071 PMID: 27834897.
 
13. Lopes-Rodrigues V, Di Luca A, Sousa D, Seca H, Meleady P, Henry M, Lima RT, O'Connor R, Vasconcelos MH
 
14. Reis FS, Sousa D, Barros L, Martins A, Morales P, Ferreira IC, Vasconcelos MH
Leccinum vulpinum Watling induces DNA damage, decreases cell proliferation and induces apoptosis on the human MCF-7 breast cancer cell line. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 90: 45-54, 2016. [Article] 
 
15. Xavier CP, Pesic M, Vasconcelos MH
Understanding Cancer Drug Resistance by Developing and Studying Resistant Cell Line Models. Current cancer drug targets 16: 226-37, 2016. [Article] 
 PMID: 26563882.
 
16. Lima RT, Sousa D, Paiva AM, Palmeira A, Barbosa J, Pedro M, Pinto MM, Sousa E, Vasconcelos MH
Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells. Molecules (Basel, Switzerland) 21: 1343, 2016. [Article] 
 
17. Pereira JM, Lopes-Rodrigues V, Xavier CP, Lima MJ, Lima RT, Ferreira IC, Vasconcelos MH
 
18. Lopes-Rodrigues V, Di Luca A, Sousa D, Seca H, Meleady P, Henry M, Lima RT, O'Connor R, Vasconcelos MH
Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells Data in Brief 6: 1023–1027, 2016. [Article; Data Paper] 
 
Special Issue: New Approaches to Counteract Drug Resistance in Cancer. Molecules (Basel, Switzerland) 22: 1, 2016. [Editorial Material] 
 
20. Reis FS, Morales P, Ferreira ICFR, Vasconcelos MH
Mushrooms as a Source of Compounds that Induce Programmed Cell Death in Tumour Cells Recent Progress in Medicinal Plants 43: ., 2016. [] 
.
 
21. Sousa D, T Lima R, Vasconcelos H
Intercellular Transfer of Cancer Drug Resistance Traits by Extracellular Vesicles Trends in molecular medicine  595-608, 2015. [Review] 
 
22. Reis FS, Lima RT, Morales P, Ferreira IC, Vasconcelos MH
Methanolic Extract of Ganoderma lucidum Induces Autophagy of AGS Human Gastric Tumor Cells. Molecules (Basel, Switzerland) 20: 17872-82, 2015. [Article] 
 
23. Lopes-Rodrigues V, Seca H, Sousa D, Sousa E, Lima RT, Vasconcelos MH
The network of P-glycoprotein and microRNAs interactions. International journal of cancer 135: 253-63, 2014. [Review] 
 doi: 10.1002/ijc.28500 PMID: 24122334.
 
Effect of miR-128 in DNA Damage of HL-60 Acute Myeloid Leukemia Cells. Current pharmaceutical biotechnology 15: 492-502, 2014. [Article] 
 PMID: 24846063.
 
25. Lima M. João, Sousa D, Lima RT, Carvalho Ana Maria, Ferreira I.C.F.R., Vasconcelos M H
 
26. Oliveira M, Reis FS, Sousa D, Tavares C, Lima RT, Ferreira IC, Santos TD, Vasconcelos MH
 doi: 10.1039/c4fo00258j PMID: 24892846.
 
27. Santos T, Oliveira M, Sousa D, Lima R T, Martins A, Ferreira I, Vasconcelos M H
 
28. Seca H, Lima RT, Vasconcelos MH
miRNAs in cancer drug resistance and drug sensitivity MicroRNAs: key regulators of oncogenesis. Editor: S. Babashah. Publisher: Springer International Publishing Switzerland  11, 2014. [] 
.
 
29. Seca H, Lima RT, Lopes-Rodrigues V, Guimaraes JE, Almeida GM, Vasconcelos MH
Targeting miR-21 Induces Autophagy and Chemosensitivity of Leukemia Cells. Current drug targets 14: 1135-43, 2013. [Article] 
 PMID: 23834154.
 
30. Queiroz MJ, Peixoto D, Calhelha RC, Soares P, Dos Santos T, Lima RT, Campos JF, Abreu RM, Ferreira IC, Vasconcelos MH
 
31. Santos T, Tavares C, Sousa D, Vaz J, Calhelha R C, Martins A, Almeida G M, Ferreira I, Vasconcelos M H
 
32. Lima RT, Seca H, Palmeira A, Fernandes MX, Castro F, Correia-da-Silva M, Nascimento MS, Sousa E, Pinto M, Vasconcelos MH
 doi: 10.1111/cbdd.12109 PMID: 23350710.
 
33. Lima Raquel T., Nascimento M . S. José, Vasconcelos M. Helena
EBV-associated cancers: Strategies for targeting the virus Microbial pathogens and strategies for combating them: science, technology and education 3: 1608-1618, 2013. [] 
.
 
34. Vaz J, Ferreira I CFR, Tavares C, Almeida G M, Martins A, Vasconcelos M H
 
35. Vaz J A, Almeida G, Ferreira I C.F.R., Martins A, Vasconcelos M H
 
36. Lima RT, Busacca S, Almeida GM, Gaudino G, Fennell DA, Vasconcelos MH
MicroRNA regulation of core apoptosis pathways in cancer. European journal of cancer (Oxford, England : 1990) 47: 163-74, 2011. [Review] 
 
37. Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH
 
 
39. Lima RT, Seca H, Brás S, Nascimento MS, Vasconcelos MH
 doi: 10.1159/000323627 PMID: 21540588.
 
40. Palmeira A, Sousa E, Fernandes MX, Pinto MM, Vasconcelos M H
Multidrug resistance reversal effects of aminated thioxanthones and interaction with cytochrome P450 3A4. Journal of Pharmacy & Pharmaceutical Sciences 3: 31-45, 2011. [Article] 
.
 
41. Lima RT, Seca H, Soares P, Nascimento MS, Vasconcelos MH
EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide. Journal of cellular biochemistry 112: 200-10, 2011. [Article] 
 doi: 10.1002/jcb.22920 PMID: 21069730.
 
42. Palmeira A, Paiva A, Sousa E, Seca H, Almeida GM, Lima RT, Fernandes MX, Pinto M, Vasconcelos MH
Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone. Chemical biology & drug design 76: 43-58, 2010. [Article] 
 
43. Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH
 
miR signatures and the role of miRs in acute myeloid leukaemia. European journal of cancer (Oxford, England : 1990) 46: 1520-1527, 2010. [Review] 
 
.
 
Chemosensitization effects of XIAP downregulation in K562 leukemia cells. Journal of chemotherapy (Florence, Italy) 18: 98-102, 2006. [Article] 
 PMID: 16572900.
 
 
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