Paula Soares
Name: Paula Soares
E-mail: psoares@ipatimup.pt
Extension: 
225570700
Academic Degree: Doctor of philosophy


Paula Soares
Paula Soares
Member of
Consultant of Ipatimup Diagnostics


Short CV
Paula Soares, BSc, PhD, is Assistant Professor of Biopathology at the Medical Faculty of Porto. She coordinates the Group of Cancer Biology at the Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup). Her main interests include oncobiology of thyroid and neuroendocrine tumors.

Highlights
Cellular and molecular biology of thyroid tumors

Supervisor of
Adriana Gaspar da Rocha, Visiting Researcher
Catarina Tavares, Affiliated Researcher
Ana Pestana, PhD Student
Antónia Póvoa, PhD Student
Bruno Carvalho, PhD Student
Elisabete Teixeira, Master Student (thesis)
Helena Pópulo, Researcher
João Vinagre, Assistant Researcher
Miguel Melo, Research Consultant
Luciana Ferreira, Affiliated Researcher
Paula Pereira, PhD Student
Raquel T. Lima, Post Doc
Ricardo Celestino, Research Consultant
Rossana Correia, Lab Technician
Sofia Pereira, Affiliated Researcher
Thalita Alves, Visiting Researcher
Valdemar Máximo, Researcher

PI (running)

PI (closed)
First Author
 
C
IF
1. Martins-Mendes D, Monteiro-Soares M, Boyko EJ, Ribeiro M, Barata P, Lima J, Soares R
The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. Journal of diabetes and its complications 28: 632-8, 2014. [Article] 
 
Papillary Thyroid Microcarcinoma: How to Diagnose and Manage this Epidemic? International journal of surgical pathology 22: 113-9, 2014. [Article] 
 
Prognostic biomarkers in thyroid cancer. Virchows Archiv : an international journal of pathology 464: 333-46, 2014. [Review] 
 
4. Celestino R, Lima J, Faustino A, Máximo V, Gouveia A, Vinagre J, Soares P, Lopes JM
 
 
Cancer: Small papillary thyroid cancers--is BRAF of prognostic value? Nature reviews. Endocrinology 7: 9-10, 2011. [Editorial Material] 
 
Is BRAF mutation screening useful for preoperative risk stratification in papillary thyroid cancer? Future oncology (London, England) 5: 1225-9, 2009. [Article] 
 doi: 10.2217/fon.09.81 PMID: 19852736.
 
8. Soares P, Trovisco V, Rocha AS, Feijão T, Rebocho AP, Fonseca E, Vieira de Castro I, Cameselle-Teijeiro J, Cardoso-Oliveira M, Sobrinho-Simões M
 
9. Soares P, Trovisco V, Rocha AS, Lima J, Castro P, Preto A, Máximo V, Botelho T, Seruca R, Sobrinho-Simões M
 
 PMID: 15357248.
 
 PMID: 10589793.
 
12. Soares P, Fonseca E, Wynford-Thomas D, Sobrinho-Simões M
 
13. Soares P, Berx G, van Roy F, Sobrinho-Simões M
E-cadherin gene alterations are rare events in thyroid tumors. International journal of cancer 70: 32-8, 1997. [Article] 
 PMID: 8985087.
 
14. Soares P, dos Santos NR, Seruca R, Lothe RA, Sobrinho-Simões M
Benign and malignant thyroid lesions show instability at microsatellite loci. European journal of cancer (Oxford, England : 1990) 33: 293-6, 1997. [Article] 
 PMID: 9135503.
 
Recent advances in cytometry, cytogenetics and molecular genetics of thyroid tumours and tumour-like lesions. Pathology, research and practice 191: 304-17, 1995. [Article; Proceedings Paper] 
 PMID: 7479347.
 
16. Soares P, Cameselle-Teijeiro J, Sobrinho-Simões M
 PMID: 8200621.
 
Expression of C-erb B2 in tumours and tumour-like lesions of the thyroid. International journal of cancer 56: 459-61, 1994. [Letter] 
 PMID: 7906256.
 
 PMID: 7910779.
 
Senior Author
 
C
IF
 doi: 10.1530/EJE-16-0740 PMID: 27760791.
 
2. Melo M, Gaspar da Rocha A, Batista R, Vinagre J, Martins MJ, Costa G, Ribeiro C, Carrilho F, Leite V, Lobo C, Cameselle-Teijeiro JM, Cavadas B, Pereira L, Sobrinho-Simões M, Soares P
TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease. The Journal of clinical endocrinology and metabolism 102: 1898-1907, 2017. [Article] 
 
3. Amorim JP, Santos G, Vinagre J, Soares P
 
 doi: 10.1530/EJE-15-0577 PMID: 26811408.
 
5. Vinagre J, Nabais J, Pinheiro J, Batista R, Oliveira RC, Gonçalves AP, Pestana A, Reis M, Mesquita B, Pinto V, Lyra J, Cipriano MA, Ferreira MG, Lopes JM, Sobrinho-Simões M, Soares P
 doi: 10.1038/srep29714 PMID: 27411289.
 
 
7. Tavares C, Coelho MJ, Melo M, da Rocha AG, Pestana A, Batista R, Salgado C, Eloy C, Ferreira L, Rios E, Sobrinho-Simões M, Soares P
pmTOR is a marker of aggressiveness in papillary thyroid carcinomas. Surgery 160: 1582-1590, 2016. [Article] 
 
8. Boaventura P, Durães C, Mendes A, Costa NR, Chora I, Ferreira S, Araújo E, Lopes P, Rosa G, Marques P, Bettencourt P, Oliveira I, Costa F, Ramos I, Teles MJ, Guimarães JT, Sobrinho-Simões M, Soares P
 
Coexistence of TERT Promoter and BRAF Mutations in Papillary Thyroid Carcinoma: Added Value in Patient Prognosis? Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33: 667-8, 2015. [Letter] 
 
10. Pópulo H, Caldas R, Lopes JM, Pardal J, Máximo V, Soares P
 
RE: TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma. Journal of the National Cancer Institute 107: 1, 2015. [Letter] 
 doi: 10.1093/jnci/djv049 PMID: 25755155.
 
12. Melo M, da Rocha AG, Vinagre J, Batista R, Peixoto J, Tavares C, Celestino R, Almeida A, Salgado C, Eloy C, Castro P, Prazeres H, Lima J, Amaro T, Lobo C, Martins MJ, Moura M, Cavaco B, Leite V, Cameselle-Teijeiro JM, Carrilho F, Carvalheiro M, Máximo V, Sobrinho-Simões M, Soares P
TERT Promoter Mutations Are a Major Indicator of Poor Outcome in Differentiated Thyroid Carcinomas. The Journal of clinical endocrinology and metabolism 99: E754-65, 2014. [Article] 
 
Telomerase promoter mutations in cancer: an emerging molecular biomarker? Virchows Archiv : an international journal of pathology 465: 119-33, 2014. [Review] 
 
14. Pópulo H, Boaventura P, Vinagre J, Batista R, Mendes A, Caldas R, Pardal J, Azevedo F, Honavar M, Guimarães I, Manuel Lopes J, Sobrinho-Simões M, Soares P
TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation. The Journal of investigative dermatology 134: 2251-7, 2014. [Article] 
 
15. Santos LR, Durães C, Mendes A, Prazeres H, Alvelos MI, Moreira CS, Canedo P, Esteves C, Neves C, Carvalho D, Sobrinho-Simões M, Soares P
A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility. The Journal of clinical endocrinology and metabolism 99: E719-23, 2014. [Article] 
 
16. Lyra J, Vinagre J, Batista R, Pinto V, Prazeres H, Rodrigues F, Eloy C, Sobrinho-Simões M, Soares P
mTOR activation in medullary thyroid carcinoma with RAS mutation. European journal of endocrinology 171: 633-40, 2014. [Article] 
 doi: 10.1530/EJE-14-0389 PMID: 25163725.
 
17. Durães C, Moreira CS, Alvelos I, Mendes A, Santos LR, Machado JC, Melo M, Esteves C, Neves C, Sobrinho-Simões M, Soares P
 
 
19. Boaventura P, Pereira D, Mendes A, Batista R, da Silva AF, Guimarães I, Honavar M, Teixeira-Gomes J, Lopes JM, Máximo V, Soares P
 
20. Vinagre J, Almeida A, Pópulo H, Batista R, Lyra J, Pinto V, Coelho R, Celestino R, Prazeres H, Lima L, Melo M, Rocha AG, Preto A, Castro P, Castro L, Pardal F, Lopes JM, Santos LL, Reis RM, Cameselle-Teijeiro J, Sobrinho-Simões M, Lima J, Máximo V, Soares P
Frequency of TERT promoter mutations in human cancers. Nature communications 4: 2185, 2013. [Article] 
 doi: 10.1038/ncomms3185 PMID: 23887589.
 
21. Melo M, Costa G, Ribeiro C, Carrilho F, Martins MJ, da Rocha AG, Sobrinho-Simões M, Carvalheiro M, Soares P
Stimulated Thyroglobulin at Recombinant Human TSH-Aided Ablation Predicts Disease-free Status One Year Later. The Journal of clinical endocrinology and metabolism 98: 4364-72, 2013. [Article] 
 
22. Boaventura P, Pereira D, Celestino R, Mendes A, Nakasawa T, Teixeira-Gomes J, Sobrinho-Simões M, Soares P
Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment. European journal of endocrinology 169: 673-679, 2013. [Article] 
 doi: 10.1530/EJE-13-0543 PMID: 23966419.
 
23. Alvelos MI, Vinagre J, Fonseca E, Barbosa E, Teixeira-Gomes J, Sobrinho-Simões M, Soares P
 doi: 10.1530/EJE-12-0327 PMID: 23093699.
 
24. Pópulo H, Tavares S, Faustino A, Nunes JB, Lopes JM, Soares P
 doi: 10.7717/peerj.104 PMID: 23904987.
 
25. Prazeres H, Salgado C, Duarte C, Soares P
LRP1B (low density lipoprotein receptor-related protein 1B) Atlas Genet Cytogenet Oncol Haematol  ., 2013. [] 
.
 
26. Melo M, Costa G, Carrilho F, Soares P
.
 
The mTOR Signalling Pathway in Human Cancer. International journal of molecular sciences 13: 1886-918, 2012. [Review] 
 
28. Faustino A, Couto JP, Pópulo H, Rocha AS, Pardal F, Cameselle-Teijeiro JM, Lopes JM, Sobrinho-Simões M, Soares P
mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism 97: E1139-49, 2012. [Article] 
 
29. Couto JP, Almeida A, Daly L, Sobrinho-Simões M, Bromberg JF, Soares P
 
30. Prazeres H, Torres J, Rodrigues F, Pinto M, Pastoriza MC, Gomes D, Cameselle-Teijeiro J, Vidal A, Martins TC, Sobrinho-Simões M, Soares P
 
Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas. The British journal of ophthalmology 95: 715-9, 2011. [Article] 
 
32. Goncalves AP, Videira A, Maximo V, Soares P
 PMID: 21857110.
 
33. Prazeres H, Torres J, Rodrigues F, Couto JP, Vinagre J, Sobrinho-Simões M, Soares P
 doi: 10.4061/2011/678357 PMID: 21765992.
 
34. Sobrinho-Simões M, Magalhães J, Soares P
Hot topics in papillary thyroid carcinoma. International journal of surgical pathology 18: 190S-193S, 2010. [Article; Proceedings Paper] 
 
Intragenic mutations in thyroid cancer. Endocrinology and metabolism clinics of North America 37: 333-62, viii, 2008. [Review] 
 
36. Rocha AS, Marques R, Bento I, Soares R, Magalhães J, de Castro IV, Soares P
 doi: 10.1677/JOE-06-0009 PMID: 17210745.
 
Molecular pathology of well-differentiated thyroid carcinomas. Virchows Archiv : an international journal of pathology 447: 787-93, 2005. [Review] 
 
38. Rocha AS, De Wever O, Moreira S, Costa MJ, Vandekerckhove J, Mareel M, Soares P
Mutated E-cadherin: genomic and functional characterization in thyroid cells from the KAT family. Thyroid : official journal of the American Thyroid Association 14: 902-9, 2004. [Article] 
 
 PMID: 12075405.
 
 PMID: 12234063.
 
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