Valdemar Máximo
Name: Valdemar Máximo
Academic Degree: PhD

Valdemar Máximo
Valdemar Máximo
Member of

Short CV
Valdemar Máximo (VM) graduated in Biology in 1994 in Coimbra University where he continued as a Master student, in 1995/1996 studying the role of mitochondrial dysfunction in schizophrenia. VM did his PhD in 2001 at the Faculty of Medicine of the University of Porto (FMUP) in a project developed at Ipatimup and Ludwig-Maximilians-University Munich. Due to his expertise in mitochondria, VM introduced at Ipatimup the interest on the role played by mitochondrial abnormalities in cancer. As a Post-doc he continued focusing his research on this topic, clarifying the role mtDNA abnormalities in tumor development leading to his recognition as an international reference scientist in the field. In 2007, VM was hired as a Ciência 2007 researcher at Ipatimup and since then he built a research team focusing on one of the hottest areas of cancer research – cancer metabolism. VM has supervised MSc and PhD students as well as Post-docs. Presently, VM is a PI of a team studying – Cancer as a metabolic disease. VM is a part-time Invited Associate Professor of Biopathology in FMUP. Besides under-graduate teaching he is involved in post-graduate lecturing and coordination of Master and PhD Programs.


Supervisor of
Mariana Gonçalves, Master Student (theoretical phase)
MSc student
Marta Cardoso, Fellow
Research Fellowship (MSc)
Nuno Jesus, PhD Student
PhD student

PI (running)

PI (closed)
First Author
Oncocytic lesions of the thyroid, kidney, salivary glands, adrenal cortex, and parathyroid glands. International journal of surgical pathology 22: 33-6, 2014. [Review] 
The biology and the genetics of Hurthle cell tumors of the thyroid. Endocrine-related cancer 19: R131-47, 2012. [Review] 
 doi: 10.1530/ERC-11-0354 PMID: 22514109.
3. Celestino R, Lima J, Faustino A, Máximo V, Gouveia A, Vinagre J, Soares P, Lopes JM
Mitochondria and cancer. Virchows Archiv : an international journal of pathology 454: 481-95, 2009. [Review] 
5. Máximo V, Lima J, Soares P, Silva A, Bento I, Sobrinho-Simões M
GRIM-19 in Health and Disease. Advances in anatomic pathology 15: 46-53, 2008. [Editorial Material] 
6. Máximo V, Botelho T, Capela J, Soares P, Lima J, Taveira A, Amaro T, Barbosa AP, Preto A, Harach HR, Williams D, Sobrinho-Simões M
7. Máximo V, Lima J, Soares P, Botelho T, Gomes L, Sobrinho-Simões M
9. Máximo V, Soares P, Lima J, Cameselle-Teijeiro J, Sobrinho-Simões M
 PMID: 12000737.
10. Máximo V, Soares P, Seruca R, Rocha AS, Castro P, Sobrinho-Simões M
 PMID: 11550281.
Hürthle cell tumours of the thyroid. A review with emphasis on mitochondrial abnormalities with clinical relevance. Virchows Archiv : an international journal of pathology 437: 107-15, 2000. [Review] 
 PMID: 10993269.
Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid. The Journal of pathology 192: 561-2, 2000. [Letter] 
Mitochondrial DNA alteration in gastric cancer. Gastroenterology 119: 1808-9, 2000. [Letter] 
 PMID: 11187439.
 PMID: 10658535.
 PMID: 9793208.
Senior Author
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma. European thyroid journal 9: 296-303, 2021. [Article] 
 doi: 10.1159/000509183 PMID: 33718253.
2. Canberk S, Lima AR, Pinto M, Máximo V
Epigenomics in Hurthle Cell Neoplasms: Filling in the Gaps Towards Clinical Application. Frontiers in endocrinology 12: 674666, 2021. [Review] 
4. Lima AR, Correia M, Santos L, Tavares C, Rios E, Canberk S, Soares P, Sobrinho-Simões M, Melo M, Máximo V
5. Lima AR, Santos L, Correia M, Soares P, Sobrinho-Simões M, Melo M, Máximo V
6. Donner LR, Maximo V
Oncocytic Melanoma: A Study of a Rare Entity. The American Journal of dermatopathology 40: 854-856, 2018. [Article] 
7. Almeida LMCA, Silva R, Cavadas B, Lima J, Pereira L, Soares P, Sobrinho-Simões M, Lopes JM, Máximo V
 doi: 10.14670/HH-11-863 PMID: 28028797.
8. Correia M, Pinheiro P, Batista R, Soares P, Sobrinho-Simões M, Máximo V
Etiopathogenesis of oncocytomas. Seminars in cancer biology 47: 82-94, 2017. [Review] 
9. Boaventura P, Pereira D, Mendes A, Batista R, da Silva AF, Guimarães I, Honavar M, Teixeira-Gomes J, Lopes JM, Máximo V, Soares P
10. Moreira S, Correia M, Soares P, Máximo V
GRIM-19 function in cancer development. Mitochondrion 11: 693-9, 2011. [Review] 
11. Gonçalves AP, Videira A, Soares P, Máximo V
Warthin's tumour. Virchows Archiv : an international journal of pathology 448: 877-8, 2006. [Letter] 
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