1. Oliveira C, Pinheiro H, Figueiredo J, Seruca R, Carneiro F

Familial gastric cancer: genetic susceptibility, pathology, and implications for management. The Lancet. Oncology 16: e60-e70, 2015. [Review] 

 doi: 10.1016/S1470-2045(14)71016-2 PMID: 25638682.

 

2. Oliveira C, Pinheiro H, Figueiredo J, Seruca R, Carneiro F

E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer. Progress in molecular biology and translational science 116: 337-59, 2013. [Review; Book Chapter] 

 doi: 10.1016/B978-0-12-394311-8.00015-7 PMID: 23481202.

 

3. Oliveira C, Seruca R, Hoogerbrugge N, Ligtenberg M, Carneiro F

Clinical utility gene card for: Hereditary diffuse gastric cancer (HDGC). European journal of human genetics : EJHG 21: ., 2013. [Editorial Material] 

 doi: 10.1038/ejhg.2012.247 PMID: 23443028.

 

4. Oliveira C, Senz J, Kaurah P, Pinheiro H, Sanges R, Haegert A, Corso G, Schouten J, Fitzgerald R, Vogelsang H, Keller G, Dwerryhouse S, Grimmer D, Chin SF, Yang HK, Jackson CE, Seruca R, Roviello F, Stupka E, Caldas C, Huntsman D

Germline CDH1 deletions in hereditary diffuse gastric cancer families. Human molecular genetics 18: 1545-55, 2009. [Article] 

 doi: 10.1093/hmg/ddp046 PMID: 19168852.

 

5. Oliveira C, Sousa S, Pinheiro H, Karam R, Bordeira-Carriço R, Senz J, Kaurah P, Carvalho J, Pereira R, Gusmão L, Wen X, Cipriano MA, Yokota J, Carneiro F, Huntsman D, Seruca R

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. Gastroenterology 136: 2137-48, 2009. [Article] 

 doi: 10.1053/j.gastro.2009.02.065 PMID: 19269290.

 

6. Oliveira C, Seruca R, Carneiro F

Hereditary gastric cancer. Best practice & research. Clinical gastroenterology 23: 147-57, 2009. [Article] 

 doi: 10.1016/j.bpg.2009.02.003 PMID: 19414142.

 

7. Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S, Carneiro F, Seruca R

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene 26: 158-63, 2007. [Article] 

 doi: 10.1038/sj.onc.1209758 PMID: 16953233.

 

8. Oliveira C, Seruca R, Carneiro F

Genetics, pathology, and clinics of familial gastric cancer. International journal of surgical pathology 14: 21-33, 2006. [Review] 

 PMID: 16501831.

 

9. Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene 24: 7630-4, 2005. [Article] 

 doi: 10.1038/sj.onc.1208906 PMID: 16007118.

 

10. Oliveira C, Moreira H, Seruca R, de Oliveira MC, Carneiro F

Role of pathology in the identification of hereditary diffuse gastric cancer: report of a Portuguese family. Virchows Archiv : an international journal of pathology 446: 181-4, 2005. [Article] 

 doi: 10.1007/s00428-004-1156-4 PMID: 15735979.

 

11. Oliveira C, Westra JL, Arango D, Ollikainen M, Domingo E, Ferreira A, Velho S, Niessen R, Lagerstedt K, Alhopuro P, Laiho P, Veiga I, Teixeira MR, Ligtenberg M, Kleibeuker JH, Sijmons RH, Plukker JT, Imai K, Lage P, Hamelin R, Albuquerque C, Schwartz S, Lindblom A, Peltomaki P, Yamamoto H, Aaltonen LA, Seruca R, Hofstra RM

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status. Human molecular genetics 13: 2303-11, 2004. [Article] 

 doi: 10.1093/hmg/ddh238 PMID: 15294875.

 

12. Oliveira C, Ferreira P, Nabais S, Campos L, Ferreira A, Cirnes L, Alves CC, Veiga I, Fragoso M, Regateiro F, Dias LM, Moreira H, Suriano G, Machado JC, Lopes C, Castedo S, Carneiro F, Seruca R

E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. European journal of cancer (Oxford, England : 1990) 40: 1897-903, 2004. [Article] 

 doi: 10.1016/j.ejca.2004.04.027 PMID: 15288293.

 

13. Oliveira C, de Bruin J, Nabais S, Ligtenberg M, Moutinho C, Nagengast FM, Seruca R, van Krieken H, Carneiro F

Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. Oncogene 23: 2236-40, 2004. [Article] 

 doi: 10.1038/sj.onc.1207335 PMID: 14661064.

 

14. Oliveira C, Suriano G, Ferreira P, Canedo P, Kaurah P, Mateus R, Ferreira A, Ferreira AC, Oliveira MJ, Figueiredo C, Carneiro F, Keller G, Huntsman D, Machado JC, Seruca R

Genetic screening for familial gastric cancer. Hereditary Cancer in Clinical Practice 2: 51-64, 2004. [] 

 doi: 10.1186/1897-4287-2-2-51 PMID: 20233471.

 

15. Oliveira C, Pinto M, Duval A, Brennetot C, Domingo E, Espín E, Armengol M, Yamamoto H, Hamelin R, Seruca R, Schwartz S

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency. Oncogene 22: 9192-6, 2003. [Article] 

 doi: 10.1038/sj.onc.1207061 PMID: 14668801.

 

16. Oliveira C, Seruca R, Caldas C

Genetic screening for hereditary diffuse gastric cancer. Expert review of molecular diagnostics 3: 201-15, 2003. [Review] 

 doi: 10.1586/14737159.3.2.201 PMID: 12647996.

 

17. Oliveira C, Bordin MC, Grehan N, Huntsman D, Suriano G, Machado JC, Kiviluoto T, Aaltonen L, Jackson CE, Seruca R, Caldas C

Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred. Human mutation 19: 510-7, 2002. [Article] 

 doi: 10.1002/humu.10068 PMID: 11968083.

 

18. Oliveira C, Seruca R, Seixas M, Sobrinho-Simões M

The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different "target genes": a study of the TGFbeta RII, IGFII R, and BAX genes. The American journal of pathology 153: 1211-9, 1998. [Article] 

 PMID: 9777952.

 

1. Garrido L, Nercio T, Leal R, Guimaraes R, Ferro L, Vilarinho L, Costa S, Magalhaes A, Mesquita AS, Pereira AF, Gullo I, Pinheiro H, Sousa S, Carvalho B, Neto AP, Capela L, Teixeira C, Fareleira A, Devezas V, Macedo G, Preto J, Barbosa J, Baptista M, Pinto G, Damasceno M, Fougo JL, Costa-Maia J, Fernandes S, Carneiro F, Castedo S, Oliveira C

Genetic counselling in hereditary diffuse gastric cancer: economical and psycho-social impact European journal of human genetics : EJHG 27: 673-674, 2019. [Meeting Abstract] 

.

 

2. Jose CS, Ferro A, Oliveira P, Carvalho J, Pinheiro H, Huntsman D, Acuna-Hidalgo R, Mundlos S, Oliveira C

CDH1 intronic Cis-Regulatory Elements control CDH1 gene tissue-specific expression European journal of human genetics : EJHG 27: 1609-1610, 2019. [Meeting Abstract] 

.

 

3. Garrido L, Leal R, Aguiar A, Seixas S, Ferro L, Vilarinho L, Gullo I, Devezas V, Oliveira R, Fernandes S, Magalhaes A, Baptista M, Carneiro F, Castedo S, Oliveira C

The first CDH1 founder mutation in Portugal: Risk assessment and clinical management European journal of human genetics : EJHG 27: 1787-1787, 2019. [Meeting Abstract] 

.

 

4. Rocha S, Teles SP, Azevedo M, Oliveira P, Carvalho J, Oliveira C

Gastric Cancer Extracellular Vesicles Tune the Migration and Invasion of Epithelial and Mesenchymal Cells in a Histotype-Dependent Manner. International journal of molecular sciences 20: ., 2019. [Article] 

 doi: 10.3390/ijms20112608 PMID: 31141946.

 

5. Matos R, Mesquita B, Oliveira P, Valente S, Pinheiro H, Carvalho J, Ferro A, Huntsman D, oliveira C

lntronic cis-regulatory elements regulate CDH1 gene expression and, function Medicine 98: ., 2019. [Meeting Abstract] 

.

 

6. Lemos D, Oliveira P, Carvalho J, Jose CS, Oliveira C

Annotator: a novel custom tool for genomic variants annotation and classification European journal of human genetics : EJHG 27: 1033-1033, 2019. [Meeting Abstract] 

.

 

7. Pelaez JG, Monteiro A, Sousa L, Castedo S, Michils G, Bours V, de Putter R, Golmard L, Blanluet M, Colas C, Benusiglio P, Aretz S, Spier I, Huneburg R, Gieldon L, Schrock E, Holinski-Feder E, Steinke V, Calistri D, Tedaldi G, Nadia-Ranzani G, Genuardi M, Silveira C, Krajc M, Blatnik A, Novakovic S, Patino-Garcia A, Soto J, Lazaro C, Capella G, Brunet-Vidal J, Balmana J, Dominguez-Garrido E, Ligtenberg M, Fewings E, Fitzgerald R, Woodward E, Evans G, Hanson H, Lagerstedt-Robinson K, Bajalica-Lagercrantz S, Teixeira M, Hoogerbrugge N, Tischkowitz M, Oliveira C

European Landscape of CDH1 germline mutations: a new tool to understand hereditary diffuse gastric cancer (HDGC) European journal of human genetics : EJHG 27: 1126-1128, 2019. [Meeting Abstract] 

.

 

8. Barbosa-Matos R, Ferro A, Oliveira P, Mesquita B, Andre A, Pinheiro H, Carvalho J, Senz J, Kaurah P, Bordeira-Carrico R, Bessa J, Huntsman D, Oliveira C

Structural variations at CDH1 intronic cis-regulatory elements cause CDH1/E-cadherin loss of function European journal of human genetics : EJHG 27: 1131-1132, 2019. [Meeting Abstract] 

.

 

9. Lopes-De-Almeida M, Garrido L, Oliveira JP, Castedo S, Oliveira C

The role of medical geneticists in the integrated care offered to patients with hereditary cancer syndromes Medicine 98: 26, 2019. [] 

.

 

10. Garrido L, Nercio T, Leal R, Guimaraes R, Ferro L, Vilarinho L, Costa S, Magalhaes A, Mesquita AS, Pereira AF, Gullo I, Pinheiro H, Sousa S, Carvalho B, Neto AP, Capela L, Teixeira C, Fareleira A, Devezas V, Macedo G, Preto J, Barbosa J, Baptista M, Pinto G, Damasceno M, Fougo JL, Costa-Maia J, Fernandes S, Carneiro F, Castedo S, Oliveira C

Genetic counselling in hereditary diffuse gastric cancer: economical and psycho-social impact European journal of human genetics : EJHG 27:  864-864, 2019. [Meeting Abstract] 

.

 

11. Korsak B, Almeida GM, Rocha S, Pereira C, Mendes N, Osório H, Pereira PMR, Rodrigues JMM, Schneider RJ, Sarmento B, Tomé JPC, Oliveira C

Porphyrin modified trastuzumab improves efficacy of HER2 targeted photodynamic therapy of gastric cancer. International journal of cancer 141: 1478-1489, 2017. [Article] 

 doi: 10.1002/ijc.30844 PMID: 28639285.

 

12. Oliveira P, Carvalho J, Rocha S, Azevedo M, Reis I, Camilo V, Sousa B, Valente S, Paredes J, Almeida R, Huntsman D, Oliveira C

Dies1/VISTA expression loss is a recurrent event in gastric cancer due to epigenetic regulation. Scientific reports 6: 34860, 2016. [Article] 

 doi: 10.1038/srep34860 PMID: 27721458.

 

13. Queirós P, Pinheiro H, Carvalho J, Oliveira P, Gullo I, Carneiro F, Almeida GM, Oliveira C

KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity. Virchows Archiv : an international journal of pathology 467: 383-92, 2015. [Article] 

 doi: 10.1007/s00428-015-1823-7 PMID: 26318594.

 

14. Pinheiro H, Oliveira P, Oliveira C

Hereditary cancer risk assessment: challenges for the next-gen sequencing era. Frontiers in oncology 5: 62, 2015. [Editorial Material] 

 doi: 10.3389/fonc.2015.00062 PMID: 25853090.

 

15. Carvalho J, Oliveira C

Extracellular Vesicles - Powerful Markers of Cancer EVolution. Frontiers in immunology 5: 685, 2014. [Editorial Material] 

 doi: 10.3389/fimmu.2014.00685 PMID: 25628624.

 

16. Bordeira-Carriço R, Ferreira D, Mateus DD, Pinheiro H, Pêgo AP, Santos MA, Oliveira C

Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. European journal of human genetics : EJHG 22: 1085-92, 2014. [Article] 

 doi: 10.1038/ejhg.2013.292 PMID: 24424122.

 

17. Corso G, Carvalho J, Marrelli D, Vindigni C, Carvalho B, Seruca R, Roviello F, Oliveira C

Somatic mutations and deletions of the e-cadherin gene predict poor survival of patients with gastric cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 31: 868-75, 2013. [Article] 

 doi: 10.1200/JCO.2012.44.4612 PMID: 23341533.

 

18. Carvalho J, van Grieken NC, Pereira PM, Sousa S, Tijssen M, Buffart TE, Diosdado B, Grabsch H, Santos MA, Meijer G, Seruca R, Carvalho B, Oliveira C

Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer. The Journal of pathology 228: 31-44, 2012. [Article] 

 doi: 10.1002/path.4032 PMID: 22450781.

 

19. Pinho SS, Oliveira P, Cabral J, Carvalho S, Huntsman D, Gärtner F, Seruca R, Reis CA, Oliveira C

Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions. PloS one 7: e33191, 2012. [Article] 

 doi: 10.1371/journal.pone.0033191 PMID: 22427986.

 

20. Bordeira-Carriço R, Pêgo AP, Santos M, Oliveira C

Cancer syndromes and therapy by stop-codon readthrough. Trends in molecular medicine 18: 667-78, 2012. [Review] 

 doi: 10.1016/j.molmed.2012.09.004 PMID: 23044248.

 

21. Pinheiro H, Carvalho J, Oliveira P, Ferreira D, Pinto MT, Osório H, Licastro D, Bordeira-Carriço R, Jordan P, Lazarevic D, Sanges R, Stupka E, Huntsman D, Seruca R, Oliveira C

Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. Human molecular genetics 21: 4253-69, 2012. [Article] 

 doi: 10.1093/hmg/dds248 PMID: 22752307.

 

22. Fitzgerald RC, Hardwick R, Huntsman D, Carneiro F, Guilford P, Blair V, Chung DC, Norton J, Ragunath K, Van Krieken JH, Dwerryhouse S, Caldas C, Linkage Consortium International Gastric Cancer

Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research. Journal of medical genetics 47: 436-44, 2010. [Article] 

 doi: 10.1136/jmg.2009.074237 PMID: 20591882.

 

23. Pinheiro H, Bordeira-Carriço R, Seixas S, Carvalho J, Senz J, Oliveira P, Inácio P, Gusmão L, Rocha J, Huntsman D, Seruca R, Oliveira C

Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. Human molecular genetics 19: 943-52, 2010. [Article] 

 doi: 10.1093/hmg/ddp537. PMID: 19965908.

 

24. Karam R, Carvalho J, Bruno I, Graziadio C, Senz J, Huntsman D, Carneiro F, Seruca R, Wilkinson MF, Oliveira C

The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. Oncogene 27: 4255-60, 2008. [Article] 

 doi: 10.1038/onc.2008.62 PMID: 18427545.

 

25. Sobrinho-Simões M, Oliveira C

Different types of epithelial cadherin alterations play different roles in human carcinogenesis. Advances in anatomic pathology 9: 329-37, 2002. [Article] 

 PMID: 12409641.