Céu Figueiredo
Name: Céu Figueiredo
E-mail: cfigueiredo@ipatimup.pt
Academic Degree: Doctor of philosophy

Céu Figueiredo
Céu Figueiredo
Member of
Consultant of Ipatimup Diagnostics

Short CV
BSc in Biology (1993), MSc in Oncobiology (1996), and PhD in Human Biology (2000). Ceu Figueiredo is a Principal Investigator at i3S/Ipatimup and an Assistant Professor at the Department of Pathology at the Faculty of Medicine of the University of Porto. She has published over 90 peer-reviewed journal articles and six book chapters, and has one patent. Her research work has been cited more than 4.500 times (h-index 33). She has coordinated and participated in several major research projects, including national projects funded by the Foundation for Science and Technology (FCT), Agency for Innovation, Ministry of Health, and Gulbenkian Foundation, and in international projects funded by the European Commission FP6, ERA-NET Pathogenomics, and the Worldwide Cancer Research.

Ceu Figueiredo’s research has been dedicated to studying the pathogenesis of Helicobacter pylori infection, namely the epidemiology and clinical relevance of H. pylori virulence factors, and the interaction between bacterial virulence factors and human genetic susceptibility to gastric carcinoma. She is investigating the role of H. pylori virulence factors in the outcome of the infection, using clinical specimens and patient cohorts; and the role of H. pylori in epithelial cell responses and underlying signaling pathways relevant to gastric carcinoma development, using in vitro models and validation in clinical specimens. More recently, she has been studying the human gastric microbiota using next-generation sequencing of samples from the stomach of patients with different lesions.

Supervisor of
Andreia Azevedo, Post Doc
Marina Leite, Post Doc
Inês Ribeiro, PhD Student
Joana Lima, PhD Student
Joana Marques, PhD Student
Joana Melo, PhD Student
Miguel Marques, PhD Student
Rui Ferreira, Post Doc

PI (running)

PI (closed)
First Author
1. Figueiredo C, Costa S, Karameris A, Machado JC
Pathogenesis of Gastric Cancer. Helicobacter 20 Suppl 1: 30-5, 2015. [Article] 
 doi: 10.1111/hel.12254 PMID: 26372822.
2. Figueiredo C, Garcia-Gonzalez MA, Machado JC
Molecular pathogenesis of gastric cancer. Helicobacter 18 Suppl 1: 28-33, 2013. [Review] 
 doi: 10.1111/hel.12083 PMID: 24011242.
3. Figueiredo C, Machado JC, Yamaoka Y
Pathogenesis of Helicobacter pylori Infection. Helicobacter 10 Suppl 1: 14-20, 2005. [Article] 
5. Figueiredo C, Machado JC, Pharoah P, Seruca R, Sousa S, Carvalho R, Capelinha AF, Quint W, Caldas C, van Doorn LJ, Carneiro F, Sobrinho-Simões M
 PMID: 12441323.
6. Figueiredo C, Van Doorn LJ, Nogueira C, Soares JM, Pinho C, Figueira P, Quint WG, Carneiro F
 PMID: 11252403.
7. Figueiredo C, Quint W, Nouhan N, van den Munckhof H, Herbrink P, Scherpenisse J, de Boer W, Schneeberger P, Perez-Perez G, Blaser MJ, van Doorn LJ
Assessment of Helicobacter pylori vacA and cagA genotypes and host serological response. Journal of clinical microbiology 39: 1339-44, 2001. [Article] 
Molecular and Cellular Biology. Helicobacter pylori 1: 293-310, 2001. [] 
9. Figueiredo C, Quint WG, Sanna R, Sablon E, Donahue JP, Xu Q, Miller GG, Peek RM, Blaser MJ, van Doorn LJ
 PMID: 10767527.
Senior Author
1. Ferreira RM, Pinto-Ribeiro I, Wen X, Marcos-Pinto R, Dinis-Ribeiro M, Carneiro F, Figueiredo C
Helicobacter pylori cagA Promoter Region Sequences Influence CagA Expression and Interleukin 8 Secretion. The Journal of infectious diseases 213: 669-73, 2016. [Article] 
2. Costa AM, Ferreira RM, Pinto-Ribeiro I, Sougleri IS, Oliveira MJ, Carreto L, Santos MA, Sgouras DN, Carneiro F, Leite M, Figueiredo C
3. Pinto-Ribeiro I, Ferreira RM, Batalha S, Hlaing T, Wong SI, Carneiro F, Figueiredo C
4. Ferreira RM, Machado JC, Letley D, Atherton JC, Pardo ML, Gonzalez CA, Carneiro F, Figueiredo C
Clinical relevance of Helicobacter pylori vacA and cagA genotypes in gastric carcinoma. Best practice & research. Clinical gastroenterology 28: 1003-15, 2014. [Article] 
6. Bento-Miranda M, Figueiredo C
Helicobacter heilmannii sensu lato: an overview of the infection in humans. World journal of gastroenterology : WJG 20: 17779-87, 2014. [Review] 
7. Guimarães NM, Azevedo NF, Vieira MJ, Figueiredo C
Water-induced modulation of Helicobacter pylori virulence properties. Memórias do Instituto Oswaldo Cruz 109: 414-9, 2014. [Article] 
 PMID: 25075780.
10. Ferreira RM, Machado JC, Letley D, Atherton JC, Pardo ML, Gonzalez CA, Carneiro F, Figueiredo C
12. Vilarinho S, Guimarães NM, Ferreira RM, Gomes B, Wen X, Vieira MJ, Carneiro F, Godinho T, Figueiredo C
Helicobacter pylori colonization of the adenotonsillar tissue: fact or fiction? International journal of pediatric otorhinolaryngology 74: 807-11, 2010. [Article] 
13. Oliveira MJ, Costa AM, Costa AC, Ferreira RM, Sampaio P, Machado JC, Seruca R, Mareel M, Figueiredo C
 doi: 10.1086/604727 PMID: 19604117.
14. Costa AC, Pinto ML, Costa AM, Leite M, Ferreira RM, Oliveira MJ, Atherton JC, Mareel M, Figueiredo C
15. Ferreira RM, Letley D, Carneiro F, Atherton JC, Figueiredo C
16. Vilarinho S, Ferreira RM, Guimaraes N, Gomes B, Xiaogang W, Oliveira F, Freitas D, Rodrigues B, Atraca E, Pereira G, Marcal N, Carneiro F, Marques A, Godinho T, Figueiredo C
H. pylori Colonization of the Adenotonsillar Tissue: Fact or Fiction? Helicobacter 14: 364-365, 2009. [Meeting Abstract] 
17. Vilarinho S, Figueiredo C
H. pylori Colonization of the Adenotonsillar Tissue: A Literature Review Helicobacter 14: 353-353, 2009. [Meeting Abstract] 
18. Ferreira RM, Machado JC, Carneiro F, Figueiredo C
19. Oliveira MJ, Costa AC, Costa AM, Henriques L, Suriano G, Atherton JC, Machado JC, Carneiro F, Seruca R, Mareel M, Leroy A, Figueiredo C
Molecular and Cellular Biology. Helicobacter pylori 1: 293-310, 2001. [] 
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