Helena Pópulo
Name: Helena Pópulo
E-mail: hpopulo@ipatimup.pt
Academic Degree: PhD

Helena Pópulo
Helena Pópulo
Member of
Junior Researcher of Cancer Signalling & Metabolism

Short CV


Supervisor of
Luísa Gonçalves, Master Student (thesis)
MSc student

PI (running)

PI (closed)
First Author
1. Pópulo H, Nunes B, Sampaio C, Batista R, Pinto MT, Gaspar TB, Miranda-Alves L, Cai RZ, Zhang XY, Schally AV, Sobrinho-Simões M, Soares P
2. Pópulo H, Batista R, Sampaio C, Pardal J, Lopes JM, Soares P
3. Pópulo H, Caldas R, Lopes JM, Pardal J, Máximo V, Soares P
RE: TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma. Journal of the National Cancer Institute 107: 1, 2015. [Letter] 
 doi: 10.1093/jnci/djv049 PMID: 25755155.
5. Pópulo H, Boaventura P, Vinagre J, Batista R, Mendes A, Caldas R, Pardal J, Azevedo F, Honavar M, Guimarães I, Manuel Lopes J, Sobrinho-Simões M, Soares P
TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation. The Journal of investigative dermatology 134: 2251-7, 2014. [Article] 
6. Pópulo H, Tavares S, Faustino A, Nunes JB, Lopes JM, Soares P
 doi: 10.7717/peerj.104 PMID: 23904987.
The mTOR Signalling Pathway in Human Cancer. International journal of molecular sciences 13: 1886-918, 2012. [Review] 
Insights into melanoma: targeting the mTOR pathway for therapeutics. Expert opinion on therapeutic targets 16: 689-705, 2012. [Review] 
Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas. The British journal of ophthalmology 95: 715-9, 2011. [Article] 
10. Pópulo H, Soares P, Faustino A, Rocha AS, Silva P, Azevedo F, Lopes JM
mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics. Pigment cell & melanoma research 24: 254-7, 2011. [Letter] 
11. Pópulo H, Soares P, Rocha AS, Silva P, Lopes JM
Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma. Melanoma research 20: 107-17, 2010. [Article] 
Senior Author
1. Sampaio C, Domingues B, Soares P, Lopes JM, Populo H
Metabolic modulation combined with mTOR pathway inhibition may overcame cutaneous melanoma resistance to MAPK inhibitors treatment European journal of cancer (Oxford, England : 1990) 138: S23-S23, 2020. [Meeting Abstract] 
2. Domingues B, Lopes JM, Soares P, Pópulo H
Melanoma treatment in review. ImmunoTargets and therapy 7: 35-49, 2018. [Review] 
 doi: 10.2147/ITT.S134842 PMID: 29922629.
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