Soraia Melo
Name: Soraia Melo
E-mail: soraiam@ipatimup.pt
Extension: 
225570700
Academic Degree: PhD


Soraia Melo
Soraia Melo


Short CV

Soraia Melo graduated in Biology at Faculty of Science and Technology of the University of Coimbra and completed her MSc in Biology at the same institution in 2009. She developed her master’s thesis project at Faculty of Pharmacy, University of Porto, tutored by Professor Georgina Correia­da­Silva with research interest in aromatase inhibitor compounds and its biological evaluation in a specific aromatase-expressing breast cancer cell line.
Soraia Melo has been recipient in several research fellowships whose main focus was studying the pathogenic value of CDH1 germline missense variants detected in HDGC worldwide.
Recently (2021), Soraia Melo concluded a PhD in Biomedical Sciences from Faculty of Medicine of the University of Porto under the supervision of Professor Raquel Seruca. During her Portuguese Foundation for Science and Technology (FCT) funded fellowship, she worked on the impact of the E­cadherin germline missense variants on protein regulation, conformation, localization and function, underlining its extrusive abilities.


Currently, Soraia Melo is a postdoctoral fellow at the Epithelial Interactions in Cancer Group, exploring the molecular mechanisms underlying the early steps of cancer cell invasion in HDGC, with particular focuses on the cadherin-dependent signalling at the interface between wild-type and E-cadherin mutant cells.
 


Highlights

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1. Melo S, Figueiredo J, Fernandes MS, Gonçalves M, Morais-de-Sá E, Sanches JM, Seruca R
Predicting the Functional Impact of CDH1 Missense Mutations in Hereditary Diffuse Gastric Cancer. International journal of molecular sciences 18: ., 2017. [Review] 
 
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