Soraia Melo
Name: Soraia Melo
Academic Degree: PhD

Soraia Melo
Soraia Melo
Member of

Short CV

Soraia Melo graduated in Biology at Faculty of Science and Technology of the University of Coimbra and completed her MSc in Biology at the same institution in 2009. She developed her master’s thesis project at Faculty of Pharmacy, University of Porto, tutored by Professor Georgina Correia-­da-­Silva with research interest in aromatase inhibitor compounds and its biological evaluation in a specific aromatase-expressing breast cancer cell line.
Soraia Melo has been recipient in several research fellowships whose main focus was studying the pathogenic value of CDH1 germline missense variants detected in HDGC worldwide.
Recently (2021), Soraia Melo concluded a PhD in Biomedical Sciences from Faculty of Medicine of the University of Porto under the supervision of Professor Raquel Seruca. During her Portuguese Foundation for Science and Technology (FCT) funded fellowship, she worked on the impact of the E­cadherin germline missense variants on protein regulation, conformation, localization and function, underlining its extrusive abilities.

Currently, Soraia Melo is collaborating on a research project as a junior researcher between the Institute for Systems and Robotics and the Intercellular Communication and Cancer group. She has been exploring the molecular mechanisms that underlie the initial stages of cancer cell invasion in HDGC, with a particular emphasis on cadherin-dependent signaling at the interface between wild-type and E-cadherin mutant cells.


Supervisor of

PI (running)

PI (closed)
First Author
1. Melo S, Figueiredo J, Fernandes MS, Gonçalves M, Morais-de-Sá E, Sanches JM, Seruca R
Predicting the Functional Impact of CDH1 Missense Mutations in Hereditary Diffuse Gastric Cancer. International journal of molecular sciences 18: ., 2017. [Review] 
Senior Author
Send Email