Fátima Gärtner
Name: Fátima Gärtner
E-mail: fgartner@ipatimup.pt
Academic Degree: PhD, Agg

Fátima Gärtner
Fátima Gärtner
Member of

Short CV
Maria de Fátima Moutinho Gärtner is graduated in Veterinary Medicine in the Faculty of Veterinary Medicine of Nova Lisboa, University of Luanda in 1975. She did her Ph.D. Degree in Pathology in the Medical Faculty of the University of Cape Town, Republic of South Africa in 1986. She was junior researcher at Ipatimup and Faculty of Medicine, University of Porto between 1991 and 1995. She is currently a senior researcher at the Ipatimup. Fátima Gärtner is a specialist in Anatomic Pathology and a member of the European College of Veterinary Pathology (ECVP) and oncobiology with emphasis for canine and feline mammary tumours. She is a Full Professor of Pathology at the Institute of Biomedical Sciences Abel Salazar, University of Porto (ICBAS-UP) since 2006, Vice Chairman of the Scientific Council of ICBAS-UP since 2002 and director of the Department of Pathology and Molecular Immunology ICBAS-UP. Started in 1991, the in vivo research unit , Ipatimup Animal House, with a colony of athymic nude mice and has since took the supervision of the research underway in this unit. Since 2009 is director of the doctoral program of Veterinary Sciences and director of the doctoral program of Pathology and Molecular Genetics at ICBAS-UP, since 2011. She supervised several PhD and master students of Porto University as well as other portuguese and foreignuniversities. Has collaboration, in the research field as well as in teaching, with several foreign universities, particularly the University of Bologna, Italy, University of São Paulo (UESP), University of Minas Gerais (UFMG) and UNESP, Brazil. She is author and/or co-author of more than 100 articles published in indexed international journals. She is the author of a book of national circulation and wrote several chapters in books of international circulation.

Our research work will focus on the dynamic interplay between galectins and their binding sites in a spontaneous model of canine mammary tumour progression and invasion. Thus we have a few lines of ongoing research such as:
A project funded by FCT and with title: ""The role of sialylation in modulating galectin-3 functions in the metastatic process"" which will involve a series of tasks such as:
1. Assessment of the involvement of down-regulation of sialyltransferases and a possible galectin-3 recognition of sialylated TAA in increased galectin-3-binding sites expression in invading cells of CMMT.
2. Study of the expression and activity of sialidases in CMMT and their possible modulatory role of galectin-3 functions in CMMT
3. Evaluation of the effects of the treatment of CMMT xenografted in nude mice with the sialidase inhibitor Tamiflu

Supervisor of
Ana Flores, PhD Student
Nuno Mendes, Research Technician
Patrícia Barradas, PhD Student
Rita Matos, PhD Student
Sílvia Teixeira, PhD Student

PI (running)

PI (closed)
First Author
1. Gärtner F, Santos M, Gillette D, Schmitt F
Inflammatory pseudotumour of the spleen in a dog. The Veterinary record 150: 697-8, 2002. [Article] 
 PMID: 12074242.
2. Gärtner F, Geraldes M, Cassali G, Rema A, Schmitt F
Establishment and characterization of two cell lines derived from human diffuse gastric carcinomas xenografted in nude mice. Virchows Archiv : an international journal of pathology 428: 91-8, 1996. [Article] 
 PMID: 8925130.
Senior Author
1. Flores AR, Lobo J, Nunes F, Rêma A, Lopes P, Carvalho L, Bartosch C, Amorim I, Gärtner F
2. Amorim I, Taulescu MA, Day MJ, Catoi C, Reis CA, Carneiro F, Gärtner F
Canine Gastric Pathology: A Review. Journal of comparative pathology 154: 9-37, 2016. [Review] 
3. Figueira A.C., Gomes C., Mendes N., Amorim I., de Matos A.J.F., Dias-Pereira P., Gärtner F.
4. de Oliveira JT, Ribeiro C, Barros R, Gomes C, de Matos AJ, Reis CA, Rutteman GR, Gärtner F
5. Amorim I, Smet A, Alves O, Teixeira S, Saraiva AL, Taulescu M, Reis C, Haesebrouck F, Gärtner F
6. de Oliveira JT, Santos AL, Gomes C, Barros R, Ribeiro C, Mendes N, de Matos AJ, Vasconcelos MH, Oliveira MJ, Reis CA, Gärtner F
7. Figueira AC, Gomes C, Vilhena H, Miranda S, Carvalheira J, DE Matos AJ, Dias-Pereira P, Gärtner F
 PMID: 26026096.
8. Flores AR, Rêma A, Amorim I, Gartner F
Altered Expression of Claudin-1 Is Related With Malignancy in Canine Thyroid Tumors. In vivo (Athens, Greece) 29: 23-28, 2015. [Article] 
 PMID: 25600525.
9. Benazzi C, Al-Dissi A, Chau CH, Figg WD, Sarli G, de Oliveira JT, Gärtner F
Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology. TheScientificWorldJournal 2014: 919570, 2014. [Review] 
 doi: 10.1155/2014/919570 PMID: 24563633.
10. Amorim I, Freitas DP, Magalhães A, Faria F, Lopes C, Faustino AM, Smet A, Haesebrouck F, Reis CA, Gärtner F
 doi: 10.1111/hel.12125 PMID: 24689986.
11. Amorim I, Taulescu MA, Ferreira A, Rêma A, Reis CA, Faustino AM, Catoi C, Gärtner F
An immunohistochemical study of canine spontaneous gastric polyps. Diagnostic pathology 9: 166, 2014. [Article] 
12. DE Oliveira JT, DE Matos AJ, Barros R, Ribeiro C, Chen A, Hespanhol V, Rutteman GR, Gärtner F
 PMID: 24778023.
13. Figueira AC, Gomes C, de Oliveira JT, Vilhena H, Carvalheira J, de Matos AJ, Pereira PD, Gärtner F
14. Pinho SS, Carvalho S, Cabral J, Reis CA, Gärtner F
Canine tumors: a spontaneous animal model of human carcinogenesis. Translational research : the journal of laboratory and clinical medicine 159: 165-72, 2012. [Review] 
15. Tavares C, de Oliveira JT, Lopes C, Carvalheira J, Matos AJ, Rutteman G, Reis CA, Gärtner F
Mucin 6 and tn antigen expression in canine mammary tumours: correlation with pathological features. Journal of comparative pathology 147: 410-8, 2012. [Article] 
16. Figueira AC, Teodósio AS, Carvalheira J, Lacerda M, de Matos A, Gärtner F
P-cadherin expression in feline mammary tissues. Veterinary medicine international 2012: 10.1155/2012/687424, 2012. [] 
 doi: 10.1155/2012/687424 PMID: 23091776.
17. Gil da Costa RM, Rema A, Pires MA, Gärtner F
18. de Oliveira JT, Pinho SS, de Matos AJ, Hespanhol V, Reis CA, Gärtner F
MUC1 expression in canine malignant mammary tumours and relationship to clinicopathological features. Veterinary journal (London, England : 1997) 182: 491-3, 2009. [Article] 
19. Amorim IF, Faria F, Lopes C, Reis C, Faustino A, Gartner F
Helicobacter Infection in Cats of the North of Portugal Preliminary Results Helicobacter 14: 353-353, 2009. [Meeting Abstract] 
20. Pinho SS, Matos AJ, Lopes C, Marcos NT, Carvalheira J, Reis CA, Gärtner F
21. Gil da Costa RM, Rema A, Payo-Puente P, Gärtner F
22. Matos AJ, Duarte S, Lopes C, Lopes JM, Gärtner F
Splenic hamartomas in a dog. The Veterinary record 161: 308-10, 2007. [Article] 
 PMID: 17766811.
23. Gil da Costa RM, Matos E, Rema A, Lopes C, Pires MA, Gärtner F
24. Matos AJ, Lopes C, Carvalheira J, Santos M, Rutteman GR, Gärtner F
25. Matos AJ, Faustino AM, Lopes C, Rutteman GR, Gärtner F
 PMID: 16679481.
26. De Matos AJ, Lopes CC, Faustino AM, Carvalheira JG, Dos Santos MS, Rutteman GR, Gärtner Mde F
 PMID: 16827113.
27. Dias Pereira P, Carvalheira J, Gärtner F
Cell proliferation in feline normal, hyperplastic and neoplastic mammary tissue--an immunohistochemical study. Veterinary journal (London, England : 1997) 168: 180-5, 2004. [Article] 
28. Reis AL, Carvalheira J, Schmitt FC, Gärtner F
Immunohistochemical study of the expression of E-cadherin in canine mammary tumours. The Veterinary record 152: 621-4, 2003. [Article] 
 PMID: 12790166.
29. Dias Pereira P, Gärtner F
Expression of E-cadherin in normal, hyperplastic and neoplastic feline mammary tissue. The Veterinary record 153: 297-302, 2003. [Article] 
 PMID: 14509576.
30. Reis-Filho JS, Gonçalves C, Gärtner F
Rectal leiomyosarcoma in a dog and review of gastrointestinal stromal tumours. The Veterinary record 153: 215-7, 2003. [Article] 
 PMID: 12956300.
31. Dias Pereira P, Azevedo M, Gärtner F
Case of malignant biphasic mesothelioma in a dog. The Veterinary record 149: 680-1, 2001. [Article] 
 PMID: 11765328.
32. Brown PJ, Rêma A, Gartner F
Thyroglobulin, calcitonin, Ki-67 and CEA immunohistochemical staining of dog thyroid carcinomas. European Journal of  Veterinary Pathology 7: 11-16, 2001. [] 
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