Luísa Azevedo
Name: Luísa Azevedo
E-mail: lazevedo@ipatimup.pt
Extension: 
225570700
Academic Degree: Doctor of philosophy


Luísa Azevedo
Luísa Azevedo
Member of
Junior Researcher of Population Genetics


Short CV
I graduated in Biology by the Faculty of Sciences of the University of Porto (FCUP) in 1999 and in 2004 completed my PhD degree in Biology at the FCUP as the result of the work developed in the Population Genetics group of the Institute of Pathology and Molecular Immunology of the University of Porto (Ipatimup). After a post-doctoral training, I started work as principal investigator under a Ciencia 2007 position at Ipatimup studying phenotypic-genotype relationships and the evolution of dynamic molecular systems.
I started to collaborate with the FCUP as Invited Assistant Professor in 2012. I got financial support as Principal Investigator from two competitive calls from the National Science Foundation (FCT). I also have been a team member projects that result from collaborative efforts between Ipatimup and other research centers. Thus far, a total of three master and two PhD students finished their thesis under my supervision/co-supervision.

Highlights
My current research line concentrates the most relevant issues related with protein evolution, specifically on the genetic and structural basis underlying the evolution of novel functions after duplication, epistatic interactions between residues under the compensatory mutation model and the role of non-conserved co-evolving sites in the structural space.
Important characteristics of genome architecture are also being studied, namely the Transposable Elements and their association with recombination and gene duplication.

Supervisor of
Ana Cardoso, PhD Student
Catarina Serrano, PhD Student
Miguel Sousa-Castro, Research Trainee

PI (running)

PI (closed)
First Author
 
C
IF
1. Azevedo L, Oliveira AS, Amorim A
Ornithine Transcarbamylase Deficiency: Genetics Encyclopedia of Life Sciences  ., 2017. [] 
 
2. Azevedo L, Mort M, Costa AC, Silva RM, Quelhas D, Amorim A, Cooper DN
Improving the in silico assessment of pathogenicity for compensated variants. European journal of human genetics : EJHG 25: 2-7, 2016. [Editorial Material] 
 
3. Azevedo L, Serrano C, Amorim A, Cooper DN
 
4. Azevedo L, Suriano G, van Asch B, Harding RM, Amorim A
Epistatic interactions: how strong in disease and evolution? Trends in genetics : TIG 22: 581-5, 2006. [Article] 
 
5. Azevedo L, Soares PA, Quental R, Vilarinho L, Teles EL, Martins E, Diogo L, Garcia P, Cenni B, Wermuth B, Amorim A
 
6. Azevedo L, Climent C, Vilarinho L, Calafell F, Amorim A
 doi: 10.1002/humu.9268 PMID: 15300856.
 
7. Azevedo L, Stolnaja L, Tietzeova E, Hrebicek M, Hruba E, Vilarinho L, Amorim A, Dvorakova L
 PMID: 12618087.
 
8. Azevedo L, Vilarinho L, Teles EL, Amorim A
 PMID: 12175783.
 
9. Azevedo L, Calafell F, Vilarinho L, Amorim A
Haplotype analysis and phylogeny of ornithine transcarbamylase polymorphisms. Annals of human genetics 66: 379-85, 2002. [Article] 
 PMID: 12516615.
 
Senior Author
 
C
IF
1. Oliveira M, Amorim MI, Azevedo L
Authentication of plant food products: Under the magnification of Botany Forensics Nova Acta Científica Compostelana 24: 45-62, 2017. [] 
.
 
 
3. Teixeira-Silva A, Silva RM, Carneiro J, Amorim A, Azevedo L
 
 
5. Pereira-Castro I, Quental R, da Costa LT, Amorim A, Azevedo L
 
Transcriptional regulation of the human mitochondrial peptide deformylase (PDF). Biochemical and biophysical research communications 421: 825-31, 2012. [Article] 
 
7. Moleirinho A, Carneiro J, Matthiesen R, Silva RM, Amorim A, Azevedo L
 
8. Vilarinho L, Tafulo S, Sibilio M, Kok F, Fontana F, Diogo L, Venâncio M, Ferreira M, Nogueira C, Valongo C, Parenti G, Amorim A, Azevedo L
Identification of novel L2HGDH gene mutations and update of the pathological spectrum. Journal of human genetics 55: 55-8, 2010. [Article] 
 
9. Quelhas D, Quental R, Vilarinho L, Amorim A, Azevedo L
 
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