Institute of Molecular Pathology and Immunology of the University of Porto
Instituto de Patologia e Imunologia Molecular da Universidade do Porto  
 
 
Porto Cancer Meeting
 

XIII Edition

  
 
  Mismatch repair genes, Microsatellite instability, and Cancer  
3-4 May 2004
   
  e-mail: cancermeeting@ipatimup.pt
Rua Dr. Roberto Frias, s/n, 4200-465 PORTO PORTUGAL
Tel.: +351 22 557 07 00  Fax: +351 22 557 07 99
   
 

The Instituto de Patologia e Imunologia Molecular da Universidade do Porto organises, every year an international meeting on a cancer related subject. The format of this meeting is an advanced course and occupies two days and it is held in Porto. The advanced course is made within in the frame of the Doctoral Program of the University of Porto on Biology and Applied Biology (GABBA Program). Participants are PhD students of the GABBA Program, researchers of our Institute, pathologist and clinicians. The maximum number of participants is 60 and the sessions are held in a very informal environment, usually with vivid discussion.
This XIII Edition of the Porto Cancer Meeting will focus on Microsatellite instability, Mismatch repair genes and Cancer.

  
     
  PURPOSE AND ORGANISATION  
 

To create a discussion forum to solve impasses/ difficulties in the resolution of specific problems and to evaluate and develop research programs and co-ordination.

  
     
  INVITED SPEAKERS  
  A. Duval D. Shibata  
  L. Aaltonen L. Rasmussen  
  LT. da Costa M. Esteller  
  M. Perucho N. de Wind  
  P. Peltomaki R. Lothe  
  R. Hamelin R. Hofstra  
  S. Schwartz    
     
  ORGANIZERS  
  Carla Oliveira Manuel Sobrinho-Simões  
  Raquel Seruca    
     
  CHAIRPERSON  
  António Amorim Carla Oliveira  
  Jorge Rocha J. Manuel Soares  
  Manuel Teixeira Cristina Albuquerque  
  Fátima Carneiro    
     
  SECRETARIAT  
  Teresa Carona    
     
  SUPPORT  
  GABBA Program (University of Porto)  
  Fundo de Apoio à Comunidade Cientifica (FACC-FCT)  
  Câmara Municipal do Porto  
  Luso-American Foundation for Development (FLAD)  
  Bioatlântico  
  Bioportugal  
  Campo de Letras  
     
  PROGRAMME  
 
Monday, 3
08:00 Registration
08:30 Welcome Session (Manuel Sobrinho Simões)
09:00 Hereditary colorectal cancer, a population based study. (Lauri Aaltonen)
10:00 Mismatch repair genes and HNPCC. (Robert Hofstra)
11:00 Coffee break
11:30 Altered expression of MLH1, MSH2, and MSH6 in predisposition to hereditary nonpolyposis colorectal cancer. (Paivi Peltomaki)
12:30 Functional assays of pathogenic HNPCC mutant proteins. (Lene Juel Rasmussen)
13:30

Lunch break
14:30 Mutator and methylator phenotypes: genetics supersedes epigenetics in tumorigenesis. (Manuel Perucho)
15:30 How Epigenetics Hits Genetics: DNA Methylation, Genomic Instability and Gene Mutation. (Manel Esteller)
16:30 Coffee break
17:00 Mouse models to study mutagenesis. (Niels de Wind)
Tuesday, 4
09:00 Reconstruction of Tumour Histories From Somatic Microsatellite Mutations. (Darryl Shibata)
10:00 Instability and tumour evolution. (Luis T. da Costa)
11:00 Coffee break
11:30 Mononucleotide repeats and MSI - (Richard Hamelin)
12:30 Identification of immunodeficiency-related lymphomas as a new subset of tumours associated with the mutator phenotype in human. (Alex Duval)
13:30

Lunch break
14:30 Activation of WNT signaling in colorectal tumors stratified by microsatellite instability status. (Ragnhild A. Lothe)
15:30 Oncogenic BRAF in Mismatch Repair Deficient Cancers: a new kid on the block. (Simo Schwartz Jr.)
16:30 KRAS in MSI and HNPCC tumours (Carla Oliveira).
 
  PICTURES  
  Pictures from the event are here.