José Carlos Machado
Name: José Carlos Machado
E-mail: josem@ipatimup.pt
Extension: 
225570700
Academic Degree: Doctor of philosophy


José Carlos Machado
José Carlos Machado
Member of
Molecular Genetics Specialist of Ipatimup Diagnostics


Short CV

Highlights

Supervisor of
Ana Pinto, Visiting Researcher
Ana Brandão, Fellow
Carlos Resende, Assistant Researcher
Cátia Pereira, Research Technician
Cecília Durães, Researcher
Helena Ferreira, PhD Student
Joana Reis, Fellow
João Freitas, Master Student (thesis)
José Luis Costa, Investigador Auxiliar
Márcia Baixia, Research Technician
Gabriela Fernandes, PhD Student
Maria Pina, Lab Technician
Maria Quental, Research Technician
Marta Santos, Research Trainee
Paulo Canedo, Unit Manager
Raquel Silva, Young Research Technician
Regina Pinto, Lab Technician
Ricardo Pinto, PhD Student
Rui Silva, Quality manager
Sara Silva, Fellow
Tânia Pereira, Administrative Assistant

PI (running)

PI (closed)
First Author
 
C
IF
1. Machado JC, Reis J, Fernandes M, Silva R, Cirnes L, Chaudhary R, Carneiro F, Costa JL
Determining tumor mutation load using an NGS-based, target gene panel European journal of cancer (Oxford, England : 1990) 92: S4-S5, 2018. [Meeting Abstract] 
.
 
2. Machado JC, Reis J, Fernandes M, Silva R, Cirnes L, Carneiro F, Costa JL
Tumor-specific neoantigens drive T-cell clonotype convergence European journal of cancer (Oxford, England : 1990) 92: S11-S11, 2018. [Meeting Abstract] 
.
 
3. Machado JC, Figueiredo C, Canedo P, Pharoah P, Carvalho R, Nabais S, Castro Alves C, Campos ML, Van Doorn LJ, Caldas C, Seruca R, Carneiro F, Sobrinho-Simões M
 PMID: 12891537.
 
.
 
5. Machado JC, Pharoah P, Sousa S, Carvalho R, Oliveira C, Figueiredo C, Amorim A, Seruca R, Caldas C, Carneiro F, Sobrinho-Simões M
 PMID: 11606496.
 
6. Machado JC, Oliveira C, Carvalho R, Soares P, Berx G, Caldas C, Seruca R, Carneiro F, Sobrinho-Simöes M
 
 
E-cadherin mutations in gastric carcinoma. The Journal of pathology 191: 466-8, 2000. [Letter] 
 
Primary signet-ring cell carcinomas of the lung. Human pathology 31: 272, 2000. [Letter] 
 PMID: 10685649.
 
10. Machado JC, Soares P, Carneiro F, Rocha A, Beck S, Blin N, Berx G, Sobrinho-Simões M
E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas. Laboratory investigation; a journal of technical methods and pathology 79: 459-65, 1999. [Article] 
 PMID: 10211998.
 
Pattern of pS2 protein expression in premalignant and malignant lesions of gastric mucosa. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 5: 169-79, 1996. [Article] 
 PMID: 8818606.
 
12. Machado JC, Carneiro F, Ribeiro P, Blin N, Sobrinho-Simões M
pS2 protein expression in gastric carcinoma. An immunohistochemical and immunoradiometric study. European journal of cancer (Oxford, England : 1990) 32A: 1585-90, 1996. [Article] 
 PMID: 8911122.
 
Female sex hormone receptors are not involved in gastric carcinogenesis. A biochemical and immunohistochemical study. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 3 Suppl 2: 31-7, 1994. [Proceedings Paper] 
 PMID: 7735043.
 
Senior Author
 
C
IF
1. Malfertheiner P, Megraud F, O'Morain CA, Gisbert JP, Kuipers EJ, Axon AT, Bazzoli F, Gasbarrini A, Atherton J, Graham DY, Hunt R, Moayyedi P, Rokkas T, Rugge M, Selgrad M, Suerbaum S, Sugano K, El-Omar EM, European Helicobacter and Microbiota Study Group and Consensus panel EM
 
2. Figueiredo C, Camargo MC, Leite M, Fuentes-Pananá EM, Rabkin CS, Machado JC
Pathogenesis of Gastric Cancer: Genetics and Molecular Classification. Current topics in microbiology and immunology 400: 277-304, 2017. [Review; Book Chapter] 
 
3. Azevedo J, Pista A, Lisboa C, Santo I, Azevedo L, Cunha MJ, HERCOLES Study Group MJ
Epidemiology of human papillomavirus on anogenital warts in Portugal - The HERCOLES study. Journal of the European Academy of Dermatology and Venereology : JEADV 31: 1342-1348, 2017. [Article] 
 doi: 10.1111/jdv.14311 PMID: 28485812.
 
4. Figueiredo C, Camargo MC, Leite M, Fuentes-Pananá EM, Rabkin CS, Machado JC
Erratum to: Pathogenesis of Gastric Cancer: Genetics and Molecular Classification. Current topics in microbiology and immunology 400: E1, 2017. [Correction; Book Chapter] 
 
Interleukin-1B signalling leads to increased survival of gastric carcinoma cells through a CREB-C/EBPß-associated mechanism. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 19: 74-84, 2016. [] 
 
6. Figueiredo C, Costa S, Karameris A, Machado JC
Pathogenesis of Gastric Cancer. Helicobacter 20 Suppl 1: 30-5, 2015. [Article] 
 doi: 10.1111/hel.12254 PMID: 26372822.
 
7. Correia M, Casal S, Vinagre J, Seruca R, Figueiredo C, Touati E, Machado JC
Helicobacter pylori's cholesterol uptake impacts resistance to docosahexaenoic acid. International journal of medical microbiology : IJMM 304: 314-20, 2014. [Article] 
 
8. Figueiredo C, Garcia-Gonzalez MA, Machado JC
Molecular pathogenesis of gastric cancer. Helicobacter 18 Suppl 1: 28-33, 2013. [Review] 
 doi: 10.1111/hel.12083 PMID: 24011242.
 
9. Costa JL, Sousa S, Justino A, Kay T, Fernandes S, Cirnes L, Schmitt F, Machado JC
 doi: 10.1002/humu.22272 PMID: 23315985.
 
10. Malfertheiner P, Megraud F, O'Morain CA, Atherton J, Axon AT, Bazzoli F, Gensini GF, Gisbert JP, Graham DY, Rokkas T, El-Omar EM, Kuipers EJ, European Helicobacter Study Group European Helicobacter Study Group
 
11. Ferreira AC, Suriano G, Mendes N, Gomes B, Wen X, Carneiro F, Seruca R, Machado JC
 doi: 10.1093/hmg/ddr469 PMID: 21989054.
 
12. Botelho MC, Oliveira PA, Lopes C, Correia da Costa JM, Machado JC
 
13. Resende C, Ristimäki A, Machado JC
Genetic and epigenetic alteration in gastric carcinogenesis. Helicobacter 15 Suppl 1: 34-9, 2010. [Review] 
 
14. Regalo G, Resende C, Wen X, Gomes B, Durães C, Seruca R, Carneiro F, Machado JC
C/EBP alpha expression is associated with homeostasis of the gastric epithelium and with gastric carcinogenesis. Laboratory investigation; a journal of technical methods and pathology 90: 1132-9, 2010. [Article] 
 
15. Botelho M, Oliveira P, Gomes J, Gartner F, Lopes C, da Costa JM, Machado JC
Tumourigenic effect of Schistosoma haematobium total antigen in mammalian cells. International journal of experimental pathology 90: 448-53, 2009. [Article] 
 
16. Ferreira AC, Suriano G, Seruca R, Machado JC
Notch Inhibition Overturns the Apoptosis Resistance Conferred by E-cadherin Deficiency Helicobacter 14: 379-380, 2009. [Meeting Abstract] 
.
 
17. Correia MM, Michel V, Oliveira MJ, Ferreira R, Figueiredo C, Seruca R, Touati E, Machado JC
Omega 3 Docosahexaenoic Acid Inhibits H-pylori Gastric Colonization in C57BL/6 Mice Helicobacter 14: 332-333, 2009. [Meeting Abstract] 
.
 
18. Canedo P, Castanheira-Vale AJ, Lunet N, Pereira F, Figueiredo C, Gioia-Patricola L, Canzian F, Moreira H, Suriano G, Barros H, Carneiro F, Seruca R, Machado JC
The interleukin-8-251*T/*A polymorphism is not associated with risk for gastric carcinoma development in a Portuguese population. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 17: 28-32, 2008. [Article] 
 
19. Canedo P, Corso G, Pereira F, Lunet N, Suriano G, Figueiredo C, Pedrazzani C, Moreira H, Barros H, Carneiro F, Seruca R, Roviello F, Machado JC
 
20. Canedo P, Durães C, Pereira F, Regalo G, Lunet N, Barros H, Carneiro F, Seruca R, Rocha J, Machado JC
Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 17: 2416-20, 2008. [Article] 
 
Genetic changes of CEBPA in cancer: mutations or polymorphisms? Journal of clinical oncology : official journal of the American Society of Clinical Oncology 25: 2493-4; author reply 2494-5, 2007. [Letter] 
 
After Helicobacter pylori, genetic susceptibility to gastric carcinoma revisited. Helicobacter 12 Suppl 2: 45-9, 2007. [Article; Proceedings Paper] 
 
Genetic susceptibility to gastric carcinoma. Acta Endoscopica 37:  239-47, 2007. [Article] 
.
 
24. Regalo G, Canedo P, Suriano G, Resende C, Campos ML, Oliveira MJ, Figueiredo C, Rodrigues-Pereira P, Blin N, Seruca R, Carneiro F, Machado JC
 doi: 10.1002/path.2063 PMID: 16981245.
 
25. Regalo G, Wright NA, Machado JC
Trefoil factors: from ulceration to neoplasia. Cellular and molecular life sciences : CMLS 62: 2910-5, 2005. [Review] 
 
.
 
27. Carvalho R, Kayademir T, Soares P, Canedo P, Sousa S, Oliveira C, Leistenschneider P, Seruca R, Gött P, Blin N, Carneiro F, Machado JC
Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma. Laboratory investigation; a journal of technical methods and pathology 82: 1319-26, 2002. [Article] 
 PMID: 12379766.
 
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